BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

570 related articles for article (PubMed ID: 28055300)

  • 1. Multistep regulation of TFEB by MTORC1.
    Vega-Rubin-de-Celis S; Peña-Llopis S; Konda M; Brugarolas J
    Autophagy; 2017 Mar; 13(3):464-472. PubMed ID: 28055300
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis.
    Wang W; Xia Z; Farré JC; Subramani S
    Autophagy; 2018; 14(9):1574-1585. PubMed ID: 29940807
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism.
    Alesi N; Akl EW; Khabibullin D; Liu HJ; Nidhiry AS; Garner ER; Filippakis H; Lam HC; Shi W; Viswanathan SR; Morroni M; Ferguson SM; Henske EP
    Nat Commun; 2021 Jul; 12(1):4245. PubMed ID: 34253722
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.
    Martina JA; Chen Y; Gucek M; Puertollano R
    Autophagy; 2012 Jun; 8(6):903-14. PubMed ID: 22576015
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Giant Cellular Vacuoles Induced by Rare Earth Oxide Nanoparticles are Abnormally Enlarged Endo/Lysosomes and Promote mTOR-Dependent TFEB Nucleus Translocation.
    Lin J; Shi SS; Zhang JQ; Zhang YJ; Zhang L; Liu Y; Jin PP; Wei PF; Shi RH; Zhou W; Wen LP
    Small; 2016 Nov; 12(41):5759-5768. PubMed ID: 27593892
    [TBL] [Abstract][Full Text] [Related]  

  • 6. YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
    Xu Y; Ren J; He X; Chen H; Wei T; Feng W
    Autophagy; 2019 Jun; 15(6):1017-1030. PubMed ID: 30653408
    [TBL] [Abstract][Full Text] [Related]  

  • 7. mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells.
    Brown RA; Voit A; Srikanth MP; Thayer JA; Kingsbury TJ; Jacobson MA; Lipinski MM; Feldman RA; Awad O
    Dis Model Mech; 2019 Oct; 12(10):. PubMed ID: 31519738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The anti-tumor agent, Dp44mT, promotes nuclear translocation of TFEB via inhibition of the AMPK-mTORC1 axis.
    Krishan S; Sahni S; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2020 Dec; 1866(12):165970. PubMed ID: 32950675
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation.
    Wu M; Lao YZ; Tan HS; Lu G; Ren Y; Zheng ZQ; Yi J; Fu WW; Shen HM; Xu HX
    Acta Pharmacol Sin; 2019 Jul; 40(7):929-937. PubMed ID: 30333555
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity.
    Zhitomirsky B; Yunaev A; Kreiserman R; Kaplan A; Stark M; Assaraf YG
    Cell Death Dis; 2018 Dec; 9(12):1191. PubMed ID: 30546014
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
    Settembre C; Zoncu R; Medina DL; Vetrini F; Erdin S; Erdin S; Huynh T; Ferron M; Karsenty G; Vellard MC; Facchinetti V; Sabatini DM; Ballabio A
    EMBO J; 2012 Mar; 31(5):1095-108. PubMed ID: 22343943
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB.
    Hsu CL; Lee EX; Gordon KL; Paz EA; Shen WC; Ohnishi K; Meisenhelder J; Hunter T; La Spada AR
    Nat Commun; 2018 Mar; 9(1):942. PubMed ID: 29507340
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity.
    Hasegawa J; Tokuda E; Yao Y; Sasaki T; Inoki K; Weisman LS
    Mol Biol Cell; 2022 Mar; 33(3):ar26. PubMed ID: 35020443
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S; Ni HM; Chao X; Wang H; Bridges B; Kumer S; Schmitt T; Mareninova O; Gukovskaya A; De Lisle RC; Ballabio A; Pacher P; Ding WX
    Autophagy; 2019 Nov; 15(11):1954-1969. PubMed ID: 30894069
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.
    Roczniak-Ferguson A; Petit CS; Froehlich F; Qian S; Ky J; Angarola B; Walther TC; Ferguson SM
    Sci Signal; 2012 Jun; 5(228):ra42. PubMed ID: 22692423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.
    Zhang J; Wang J; Zhou Z; Park JE; Wang L; Wu S; Sun X; Lu L; Wang T; Lin Q; Sze SK; Huang D; Shen HM
    Autophagy; 2018; 14(6):1043-1059. PubMed ID: 30059277
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation.
    Marin Zapata PA; Beese CJ; Jünger A; Dalmasso G; Brady NR; Hamacher-Brady A
    BMC Cancer; 2016 Jun; 16():355. PubMed ID: 27268034
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress.
    Li D; Shao R; Wang N; Zhou N; Du K; Shi J; Wang Y; Zhao Z; Ye X; Zhang X; Xu H
    Autophagy; 2021 Apr; 17(4):872-887. PubMed ID: 32138578
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.
    Zhou J; Tan SH; Nicolas V; Bauvy C; Yang ND; Zhang J; Xue Y; Codogno P; Shen HM
    Cell Res; 2013 Apr; 23(4):508-23. PubMed ID: 23337583
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SMURF1 controls the PPP3/calcineurin complex and TFEB at a regulatory node for lysosomal biogenesis.
    Xia Q; Zheng H; Li Y; Xu W; Wu C; Xu J; Li S; Zhang L; Dong L
    Autophagy; 2024 Apr; 20(4):735-751. PubMed ID: 37909662
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.