BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 28056488)

  • 1. Molecular dynamics simulations reveal structural insights into inhibitor binding modes and functionality in human Group IIA phospholipase A
    Kim RR; Malde AK; Nematollahi A; Scott KF; Church WB
    Proteins; 2017 May; 85(5):827-842. PubMed ID: 28056488
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Can Inhibitors of Snake Venom Phospholipases A₂ Lead to New Insights into Anti-Inflammatory Therapy in Humans? A Theoretical Study.
    Sales TA; Marcussi S; da Cunha EFF; Kuca K; Ramalho TC
    Toxins (Basel); 2017 Oct; 9(11):. PubMed ID: 29068410
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Virtual analysis of structurally diverse synthetic analogs as inhibitors of snake venom secretory phospholipase A2.
    Sivaramakrishnan V; Ilamathi M; Ghosh KS; Sathish S; Gowda TV; Vishwanath BS; Rangappa KS; Dhananjaya BL
    J Mol Recognit; 2016 Jan; 29(1):22-32. PubMed ID: 26218369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structures and binding studies of the complexes of phospholipase A2 with five inhibitors.
    Shukla PK; Gautam L; Sinha M; Kaur P; Sharma S; Singh TP
    Biochim Biophys Acta; 2015 Apr; 1854(4):269-77. PubMed ID: 25541253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of novel inhibitors of Daboia russelli phospholipase A2 using the combined pharmacophore modeling approach.
    Ramakrishnan C; Joshi V; Joseph JM; Vishwanath BS; Velmurugan D
    Chem Biol Drug Des; 2014 Oct; 84(4):379-92. PubMed ID: 24703201
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Human Group IIA-Secreted Phospholipase A2 and THP-1 Monocyte Recruitment by Maslinic Acid.
    Yap WH; Ahmed N; Lim YM
    Lipids; 2016 Oct; 51(10):1153-1159. PubMed ID: 27540737
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding.
    Singh N; Jabeen T; Pal A; Sharma S; Perbandt M; Betzel C; Singh TP
    Proteins; 2006 Jul; 64(1):89-100. PubMed ID: 16596639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of a potent 2-oxoamide inhibitor of secreted phospholipase A2 guided by molecular docking calculations and molecular dynamics simulations.
    Vasilakaki S; Barbayianni E; Leonis G; Papadopoulos MG; Mavromoustakos T; Gelb MH; Kokotos G
    Bioorg Med Chem; 2016 Apr; 24(8):1683-95. PubMed ID: 26970660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective inhibition of human group IIA-secreted phospholipase A2 (hGIIA) signaling reveals arachidonic acid metabolism is associated with colocalization of hGIIA to vimentin in rheumatoid synoviocytes.
    Lee LK; Bryant KJ; Bouveret R; Lei PW; Duff AP; Harrop SJ; Huang EP; Harvey RP; Gelb MH; Gray PP; Curmi PM; Cunningham AM; Church WB; Scott KF
    J Biol Chem; 2013 May; 288(21):15269-79. PubMed ID: 23482564
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A
    Kim RR; Chen Z; Mann TJ; Bastard K; F Scott K; Church WB
    Molecules; 2020 Sep; 25(19):. PubMed ID: 32998383
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and evolutionary insights into endogenous alpha-phospholipase A2 inhibitors of Latin American pit vipers.
    Estevão-Costa MI; Fernandes CA; Mudadu Mde A; Franco GR; Fontes MR; Fortes-Dias CL
    Toxicon; 2016 Mar; 112():35-44. PubMed ID: 26806211
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of an autoantigen on the surface of apoptotic human T cells as a new protein interacting with inflammatory group IIA phospholipase A2.
    Boilard E; Bourgoin SG; Bernatchez C; Surette ME
    Blood; 2003 Oct; 102(8):2901-9. PubMed ID: 12829607
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A2 by affinity binding studies and molecular bioinformatics.
    Faure G; Gowda VT; Maroun RC
    BMC Struct Biol; 2007 Dec; 7():82. PubMed ID: 18062812
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner.
    Takada Y; Fujita M
    Adv Exp Med Biol; 2017; 925():103-115. PubMed ID: 27864802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2.
    Anilkumar NC; Sundaram MS; Mohan CD; Rangappa S; Bulusu KC; Fuchs JE; Girish KS; Bender A; Basappa ; Rangappa KS
    PLoS One; 2015; 10(7):e0131896. PubMed ID: 26196520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of the complex of the secretory phospholipase A2 from Daboia russelli pulchella with an endogenic indole derivative, 2-carbamoylmethyl-5-propyl-octahydro-indol-7-yl-acetic acid at 1.8 A resolution.
    Balasubramanya R; Chandra V; Kaur P; Singh TP
    Biochim Biophys Acta; 2005 Sep; 1752(2):177-85. PubMed ID: 16122995
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition comparison with other mammalian secreted phospholipases A2.
    Mounier CM; Luchetta P; Lecut C; Koduri RS; Faure G; Lambeau G; Valentin E; Singer A; Ghomashchi F; Béguin S; Gelb MH; Bon C
    Eur J Biochem; 2000 Aug; 267(16):4960-9. PubMed ID: 10931177
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Computational and in vitro insights on snake venom phospholipase A
    Muthusamy K; Chinnasamy S; Nagarajan S; Sivaraman T
    J Biomol Struct Dyn; 2018 Dec; 36(16):4197-4208. PubMed ID: 29171346
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
    Singh N; Jabeen T; Sharma S; Somvanshi RK; Dey S; Srinivasan A; Singh TP
    Acta Crystallogr D Biol Crystallogr; 2006 Apr; 62(Pt 4):410-6. PubMed ID: 16552142
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of a phospholipase A
    Salvador GH; Dos Santos JI; Lomonte B; Fontes MR
    Biochimie; 2017 Feb; 133():95-102. PubMed ID: 28034717
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.