These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
163 related articles for article (PubMed ID: 28057420)
1. Structure activity relationships of benzylproline-derived inhibitors of the glutamine transporter ASCT2. Singh K; Tanui R; Gameiro A; Eisenberg G; Colas C; Schlessinger A; Grewer C Bioorg Med Chem Lett; 2017 Feb; 27(3):398-402. PubMed ID: 28057420 [TBL] [Abstract][Full Text] [Related]
2. Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds. Ndaru E; Garibsingh RA; Shi Y; Wallace E; Zakrepine P; Wang J; Schlessinger A; Grewer C J Gen Physiol; 2019 Mar; 151(3):357-368. PubMed ID: 30718375 [TBL] [Abstract][Full Text] [Related]
3. 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport. Schulte ML; Khodadadi AB; Cuthbertson ML; Smith JA; Manning HC Bioorg Med Chem Lett; 2016 Feb; 26(3):1044-1047. PubMed ID: 26750251 [TBL] [Abstract][Full Text] [Related]
4. New inhibitors for the neutral amino acid transporter ASCT2 reveal its Na+-dependent anion leak. Grewer C; Grabsch E J Physiol; 2004 Jun; 557(Pt 3):747-59. PubMed ID: 15107471 [TBL] [Abstract][Full Text] [Related]
5. Interaction of the neutral amino acid transporter ASCT2 with basic amino acids. Ndaru E; Garibsingh RA; Zielewicz L; Schlessinger A; Grewer C Biochem J; 2020 Apr; 477(8):1443-1457. PubMed ID: 32242892 [TBL] [Abstract][Full Text] [Related]
6. Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity. Oppedisano F; Catto M; Koutentis PA; Nicolotti O; Pochini L; Koyioni M; Introcaso A; Michaelidou SS; Carotti A; Indiveri C Toxicol Appl Pharmacol; 2012 Nov; 265(1):93-102. PubMed ID: 23010140 [TBL] [Abstract][Full Text] [Related]
7. Defining substrate and blocker activity of alanine-serine-cysteine transporter 2 (ASCT2) Ligands with Novel Serine Analogs. Albers T; Marsiglia W; Thomas T; Gameiro A; Grewer C Mol Pharmacol; 2012 Mar; 81(3):356-65. PubMed ID: 22113081 [TBL] [Abstract][Full Text] [Related]
8. Rational design of ASCT2 inhibitors using an integrated experimental-computational approach. Garibsingh RA; Ndaru E; Garaeva AA; Shi Y; Zielewicz L; Zakrepine P; Bonomi M; Slotboom DJ; Paulino C; Grewer C; Schlessinger A Proc Natl Acad Sci U S A; 2021 Sep; 118(37):. PubMed ID: 34507995 [TBL] [Abstract][Full Text] [Related]
9. 2-Substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency. Schulte ML; Dawson ES; Saleh SA; Cuthbertson ML; Manning HC Bioorg Med Chem Lett; 2015 Jan; 25(1):113-6. PubMed ID: 25435145 [TBL] [Abstract][Full Text] [Related]
10. Ngamma-aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site. Esslinger CS; Cybulski KA; Rhoderick JF Bioorg Med Chem; 2005 Feb; 13(4):1111-8. PubMed ID: 15670919 [TBL] [Abstract][Full Text] [Related]
11. Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Scopelliti AJ; Font J; Vandenberg RJ; Boudker O; Ryan RM Nat Commun; 2018 Jan; 9(1):38. PubMed ID: 29295993 [TBL] [Abstract][Full Text] [Related]
12. Targeting of glutamine transporter ASCT2 and glutamine synthetase suppresses gastric cancer cell growth. Ye J; Huang Q; Xu J; Huang J; Wang J; Zhong W; Chen W; Lin X; Lin X J Cancer Res Clin Oncol; 2018 May; 144(5):821-833. PubMed ID: 29435734 [TBL] [Abstract][Full Text] [Related]
13. Anti-tumor effects of an antagonistic mAb against the ASCT2 amino acid transporter on KRAS-mutated human colorectal cancer cells. Hara Y; Minami Y; Yoshimoto S; Hayashi N; Yamasaki A; Ueda S; Masuko K; Masuko T Cancer Med; 2020 Jan; 9(1):302-312. PubMed ID: 31709772 [TBL] [Abstract][Full Text] [Related]
14. Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening. Colas C; Grewer C; Otte NJ; Gameiro A; Albers T; Singh K; Shere H; Bonomi M; Holst J; Schlessinger A PLoS Comput Biol; 2015 Oct; 11(10):e1004477. PubMed ID: 26444490 [TBL] [Abstract][Full Text] [Related]
15. Cryo-EM structure of the human neutral amino acid transporter ASCT2. Garaeva AA; Oostergetel GT; Gati C; Guskov A; Paulino C; Slotboom DJ Nat Struct Mol Biol; 2018 Jun; 25(6):515-521. PubMed ID: 29872227 [TBL] [Abstract][Full Text] [Related]
16. Inactivation by Hg2+ and methylmercury of the glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: Prediction of the involvement of a CXXC motif by homology modelling. Oppedisano F; Galluccio M; Indiveri C Biochem Pharmacol; 2010 Oct; 80(8):1266-73. PubMed ID: 20599776 [TBL] [Abstract][Full Text] [Related]
17. Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development. Wang Q; Hardie RA; Hoy AJ; van Geldermalsen M; Gao D; Fazli L; Sadowski MC; Balaban S; Schreuder M; Nagarajah R; Wong JJ; Metierre C; Pinello N; Otte NJ; Lehman ML; Gleave M; Nelson CC; Bailey CG; Ritchie W; Rasko JE; Holst J J Pathol; 2015 Jul; 236(3):278-89. PubMed ID: 25693838 [TBL] [Abstract][Full Text] [Related]
18. Discovery and Synthesis of Hydroxy-l-Proline Blockers of the Neutral Amino Acid Transporters SLC1A4 (ASCT1) and SLC1A5 (ASCT2). Lyda BR; Leary GP; Farnsworth J; Seaver B; Silvius D; Kavanaugh MP; Esslinger CS; Natale NR Molecules; 2024 May; 29(10):. PubMed ID: 38792190 [TBL] [Abstract][Full Text] [Related]
19. Target the human Alanine/Serine/Cysteine Transporter 2(ASCT2): Achievement and Future for Novel Cancer Therapy. Jiang H; Zhang N; Tang T; Feng F; Sun H; Qu W Pharmacol Res; 2020 Aug; 158():104844. PubMed ID: 32438035 [TBL] [Abstract][Full Text] [Related]
20. Glutamine availability up-regulates expression of the amino acid transporter protein ASCT2 in HepG2 cells and stimulates the ASCT2 promoter. Bungard CI; McGivan JD Biochem J; 2004 Aug; 382(Pt 1):27-32. PubMed ID: 15175006 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]