244 related articles for article (PubMed ID: 28065273)
1. Screening and Characterization Strategies for Nanobodies Targeting Membrane Proteins.
Veugelen S; Dewilde M; De Strooper B; Chávez-Gutiérrez L
Methods Enzymol; 2017; 584():59-97. PubMed ID: 28065273
[TBL] [Abstract][Full Text] [Related]
2. Structural biology of presenilins and signal peptide peptidases.
Tomita T; Iwatsubo T
J Biol Chem; 2013 May; 288(21):14673-80. PubMed ID: 23585568
[TBL] [Abstract][Full Text] [Related]
3. Probing the Structure and Function Relationships of Presenilin by Substituted-Cysteine Accessibility Method.
Tomita T
Methods Enzymol; 2017; 584():185-205. PubMed ID: 28065263
[TBL] [Abstract][Full Text] [Related]
4. gamma-Secretase inhibitors as molecular probes of presenilin function.
Wolfe MS
J Mol Neurosci; 2001 Oct; 17(2):199-204. PubMed ID: 11816793
[TBL] [Abstract][Full Text] [Related]
5. Novel research horizons for presenilins and γ-secretases in cell biology and disease.
De Strooper B; Annaert W
Annu Rev Cell Dev Biol; 2010; 26():235-60. PubMed ID: 20604710
[TBL] [Abstract][Full Text] [Related]
6. Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease.
Wolfe MS; De Los Angeles J; Miller DD; Xia W; Selkoe DJ
Biochemistry; 1999 Aug; 38(35):11223-30. PubMed ID: 10471271
[TBL] [Abstract][Full Text] [Related]
7. The gamma-secretase complex: machinery for intramembrane proteolysis.
Iwatsubo T
Curr Opin Neurobiol; 2004 Jun; 14(3):379-83. PubMed ID: 15194119
[TBL] [Abstract][Full Text] [Related]
8. gamma-secretases: from cell biology to therapeutic strategies.
Bergmans BA; De Strooper B
Lancet Neurol; 2010 Feb; 9(2):215-26. PubMed ID: 20129170
[TBL] [Abstract][Full Text] [Related]
9. Secretase as a target for Alzheimer's disease.
Wolfe MS
Curr Top Med Chem; 2002 Apr; 2(4):371-83. PubMed ID: 11966461
[TBL] [Abstract][Full Text] [Related]
10. Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.
Esler WP; Kimberly WT; Ostaszewski BL; Diehl TS; Moore CL; Tsai JY; Rahmati T; Xia W; Selkoe DJ; Wolfe MS
Nat Cell Biol; 2000 Jul; 2(7):428-34. PubMed ID: 10878808
[TBL] [Abstract][Full Text] [Related]
11. Membrane Dynamics of γ-Secretase Provides a Molecular Basis for β-Amyloid Binding and Processing.
Somavarapu AK; Kepp KP
ACS Chem Neurosci; 2017 Nov; 8(11):2424-2436. PubMed ID: 28841371
[TBL] [Abstract][Full Text] [Related]
12. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
Wolfe MS; Xia W; Ostaszewski BL; Diehl TS; Kimberly WT; Selkoe DJ
Nature; 1999 Apr; 398(6727):513-7. PubMed ID: 10206644
[TBL] [Abstract][Full Text] [Related]
13. The Alzheimer's disease-associated gamma-secretase complex: functional domains in the presenilin 1 protein.
Laudon H; Winblad B; Näslund J
Physiol Behav; 2007 Sep; 92(1-2):115-20. PubMed ID: 17588625
[TBL] [Abstract][Full Text] [Related]
14. Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.
Evin G; Sharples RA; Weidemann A; Reinhard FB; Carbone V; Culvenor JG; Holsinger RM; Sernee MF; Beyreuther K; Masters CL
Biochemistry; 2001 Jul; 40(28):8359-68. PubMed ID: 11444983
[TBL] [Abstract][Full Text] [Related]
15. Processive proteolysis by γ-secretase and the mechanism of Alzheimer's disease.
Wolfe MS
Biol Chem; 2012 Sep; 393(9):899-905. PubMed ID: 22944690
[TBL] [Abstract][Full Text] [Related]
16. The presenilins in Alzheimer's disease--proteolysis holds the key.
Haass C; De Strooper B
Science; 1999 Oct; 286(5441):916-9. PubMed ID: 10542139
[TBL] [Abstract][Full Text] [Related]
17. Substrate recruitment of γ-secretase and mechanism of clinical presenilin mutations revealed by photoaffinity mapping.
Fukumori A; Steiner H
EMBO J; 2016 Aug; 35(15):1628-43. PubMed ID: 27220847
[TBL] [Abstract][Full Text] [Related]
18. Toward structural elucidation of the gamma-secretase complex.
Li H; Wolfe MS; Selkoe DJ
Structure; 2009 Mar; 17(3):326-34. PubMed ID: 19278647
[TBL] [Abstract][Full Text] [Related]
19. Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH.
Dang S; Wu S; Wang J; Li H; Huang M; He W; Li YM; Wong CC; Shi Y
Proc Natl Acad Sci U S A; 2015 Mar; 112(11):3344-9. PubMed ID: 25733893
[TBL] [Abstract][Full Text] [Related]
20. Generation of monoclonal antibody fragments binding the native γ-secretase complex for use in structural studies.
Alattia JR; Schweizer C; Cacquevel M; Dimitrov M; Aeschbach L; Oulad-Abdelghani M; Fraering PC
Biochemistry; 2012 Nov; 51(44):8779-90. PubMed ID: 23066899
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]