152 related articles for article (PubMed ID: 28066558)
1. Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway.
Gai Z; Wang Q; Yang C; Wang L; Deng W; Wu G
Cell Discov; 2016; 2():16051. PubMed ID: 28066558
[TBL] [Abstract][Full Text] [Related]
2. Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling.
Xia J; Wang R; Zhang T; Ding J
Cell Discov; 2016; 2():16035. PubMed ID: 27648300
[TBL] [Abstract][Full Text] [Related]
3. Crystal structures of arginine sensor CASTOR1 in arginine-bound and ligand free states.
Zhou Y; Wang C; Xiao Q; Guo L
Biochem Biophys Res Commun; 2019 Jan; 508(2):387-391. PubMed ID: 30503338
[TBL] [Abstract][Full Text] [Related]
4. New insights into GATOR2-dependent interactions and its conformational changes in amino acid sensing.
Yang C; Sun X; Wu G
Biosci Rep; 2024 Mar; 44(3):. PubMed ID: 38372438
[TBL] [Abstract][Full Text] [Related]
5. Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Saxton RA; Chantranupong L; Knockenhauer KE; Schwartz TU; Sabatini DM
Nature; 2016 Aug; 536(7615):229-33. PubMed ID: 27487210
[TBL] [Abstract][Full Text] [Related]
6. The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
Chantranupong L; Scaria SM; Saxton RA; Gygi MP; Shen K; Wyant GA; Wang T; Harper JW; Gygi SP; Sabatini DM
Cell; 2016 Mar; 165(1):153-164. PubMed ID: 26972053
[TBL] [Abstract][Full Text] [Related]
7. Seeking mTORC1 Inhibitors Through Molecular Dynamics Simulation of Arginine Analogs Inhibiting CASTOR1.
Sun L; Li X; Pan J; Mao J; Yuan Y; Wang D; Sun W; Krueger GRF; Wang G
Cancer Genomics Proteomics; 2019; 16(6):465-479. PubMed ID: 31659101
[TBL] [Abstract][Full Text] [Related]
8. Structure of the nutrient-sensing hub GATOR2.
Valenstein ML; Rogala KB; Lalgudi PV; Brignole EJ; Gu X; Saxton RA; Chantranupong L; Kolibius J; Quast JP; Sabatini DM
Nature; 2022 Jul; 607(7919):610-616. PubMed ID: 35831510
[TBL] [Abstract][Full Text] [Related]
9. RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation.
Li T; Wang X; Ju E; da Silva SR; Chen L; Zhang X; Wei S; Gao SJ
Nat Commun; 2021 Feb; 12(1):1055. PubMed ID: 33594058
[TBL] [Abstract][Full Text] [Related]
10. Ring domains are essential for GATOR2-dependent mTORC1 activation.
Jiang C; Dai X; He S; Zhou H; Fang L; Guo J; Liu S; Zhang T; Pan W; Yu H; Fu T; Li D; Inuzuka H; Wang P; Xiao J; Wei W
Mol Cell; 2023 Jan; 83(1):74-89.e9. PubMed ID: 36528027
[TBL] [Abstract][Full Text] [Related]
11. Downregulation of CASTOR1 Inhibits Heat-Stress-Induced Apoptosis and Promotes Casein and Lipid Synthesis in Mammary Epithelial Cells.
Gai Z; Wang Y; Wang J; Fu J; Tian L; Li X; Zhao J; Gong G
J Agric Food Chem; 2022 May; 70(17):5386-5395. PubMed ID: 35442666
[TBL] [Abstract][Full Text] [Related]
12. Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Hu H; Lu X; Huang L; He Y; Liu X; Wang Y; Duan C
Metab Brain Dis; 2023 Feb; 38(2):699-708. PubMed ID: 36454504
[TBL] [Abstract][Full Text] [Related]
13. CASTORing New Light on Amino Acid Sensing.
Hallett JEH; Manning BD
Cell; 2016 Mar; 165(1):15-17. PubMed ID: 27015302
[TBL] [Abstract][Full Text] [Related]
14. Sestrin2 is a leucine sensor for the mTORC1 pathway.
Wolfson RL; Chantranupong L; Saxton RA; Shen K; Scaria SM; Cantor JR; Sabatini DM
Science; 2016 Jan; 351(6268):43-8. PubMed ID: 26449471
[TBL] [Abstract][Full Text] [Related]
15. SPOP negatively regulates mTORC1 activity by ubiquitinating Sec13.
Yang Y; Han YC; Cao Q; Wang X; Wei XD; Shang MD; Zhang XG; Li X; Hu B; Tian CY; Yang ZL; Liu KH; Wang JQ
Cell Signal; 2024 Apr; 116():111060. PubMed ID: 38242269
[TBL] [Abstract][Full Text] [Related]
16. Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling.
Jung JW; Macalino SJY; Cui M; Kim JE; Kim HJ; Song DG; Nam SH; Kim S; Choi S; Lee JW
Cell Metab; 2019 Jun; 29(6):1306-1319.e7. PubMed ID: 30956113
[TBL] [Abstract][Full Text] [Related]
17. Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.
Saxton RA; Knockenhauer KE; Wolfson RL; Chantranupong L; Pacold ME; Wang T; Schwartz TU; Sabatini DM
Science; 2016 Jan; 351(6268):53-8. PubMed ID: 26586190
[TBL] [Abstract][Full Text] [Related]
18. Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia.
Weckhuysen S; Marsan E; Lambrecq V; Marchal C; Morin-Brureau M; An-Gourfinkel I; Baulac M; Fohlen M; Kallay Zetchi C; Seeck M; de la Grange P; Dermaut B; Meurs A; Thomas P; Chassoux F; Leguern E; Picard F; Baulac S
Epilepsia; 2016 Jun; 57(6):994-1003. PubMed ID: 27173016
[TBL] [Abstract][Full Text] [Related]
19. An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway.
Liu GY; Jouandin P; Bahng RE; Perrimon N; Sabatini DM
bioRxiv; 2023 May; ():. PubMed ID: 37292894
[TBL] [Abstract][Full Text] [Related]
20. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.
Kim JS; Ro SH; Kim M; Park HW; Semple IA; Park H; Cho US; Wang W; Guan KL; Karin M; Lee JH
Sci Rep; 2015 Mar; 5():9502. PubMed ID: 25819761
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
