BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 28067996)

  • 1. Virtual screening, SAR, and discovery of 5-(indole-3-yl)-2-[(2-nitrophenyl)amino] [1,3,4]-oxadiazole as a novel Bcl-2 inhibitor.
    Ziedan NI; Hamdy R; Cavaliere A; Kourti M; Prencipe F; Brancale A; Jones AT; Westwell AD
    Chem Biol Drug Des; 2017 Jul; 90(1):147-155. PubMed ID: 28067996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2.
    Hamdy R; Elseginy SA; Ziedan NI; El-Sadek M; Lashin E; Jones AT; Westwell AD
    Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33256166
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2-amines as Bcl-2 inhibitory anticancer agents.
    Hamdy R; Ziedan NI; Ali S; Bordoni C; El-Sadek M; Lashin E; Brancale A; Jones AT; Westwell AD
    Bioorg Med Chem Lett; 2017 Feb; 27(4):1037-1040. PubMed ID: 28087272
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bisindole-oxadiazole hybrids, T3P
    Kamath PR; Joseph MM; Abdul Salam AA; Therakathinal ST; Sunil D; Biswas S; Pai KSR
    J Biochem Mol Toxicol; 2017 Nov; 31(11):. PubMed ID: 28724188
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel histone deacetylase 8-selective inhibitor 1,3,4-oxadiazole-alanine hybrid induces apoptosis in breast cancer cells.
    Pidugu VR; Yarla NS; Bishayee A; Kalle AM; Satya AK
    Apoptosis; 2017 Nov; 22(11):1394-1403. PubMed ID: 28840369
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rationale Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4-oxadiazole Analogues.
    Ahsan MJ; Choupra A; Sharma RK; Jadav SS; Padmaja P; Hassan MZ; Al-Tamimi ABS; Geesi MH; Bakht MA
    Anticancer Agents Med Chem; 2018; 18(1):121-138. PubMed ID: 28425854
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 1-Phenyl-1H-indole derivatives as a new class of Bcl-2/Mcl-1 dual inhibitors: Design, synthesis, and preliminary biological evaluation.
    Xu G; Liu T; Zhou Y; Yang X; Fang H
    Bioorg Med Chem; 2017 Oct; 25(20):5548-5556. PubMed ID: 28866374
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of quinoxaline-1,3,4-oxadiazole hybrid derivatives as potent inhibitors of the anti-apoptotic Bcl-2 protein.
    Ono Y; Ninomiya M; Kaneko D; Sonawane AD; Udagawa T; Tanaka K; Nishina A; Koketsu M
    Bioorg Chem; 2020 Nov; 104():104245. PubMed ID: 32911196
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, in silico and biological evaluation of new indole based oxadiazole derivatives targeting estrogen receptor alpha.
    Kaur K; Verma H; Gangwar P; Jangid K; Dhiman M; Kumar V; Jaitak V
    Bioorg Chem; 2024 Jun; 147():107341. PubMed ID: 38593531
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening.
    Enyedy IJ; Ling Y; Nacro K; Tomita Y; Wu X; Cao Y; Guo R; Li B; Zhu X; Huang Y; Long YQ; Roller PP; Yang D; Wang S
    J Med Chem; 2001 Dec; 44(25):4313-24. PubMed ID: 11728179
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and docking studies of novel 4-aminophenol-1,2,4-oxadiazole hybrids as apoptosis inducers against triple negative breast cancer cells targeting MAP kinase.
    Dhanalakshmi B; Anil Kumar BM; Srinivasa Murthy V; Srinivasa SM; Vivek HK; Sennappan M; Rangappa S
    J Biomol Struct Dyn; 2024 Jul; 42(11):5841-5857. PubMed ID: 37529915
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, modelling studies and biological evaluation of 1,3,4-oxadiazole derivatives as potent anticancer agents targeting thymidine phosphorylase enzyme.
    Bajaj S; Kumar MS; Tinwala H; Yc M
    Bioorg Chem; 2021 Jun; 111():104873. PubMed ID: 33845381
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Indole-coumarin-thiadiazole hybrids: An appraisal of their MCF-7 cell growth inhibition, apoptotic, antimetastatic and computational Bcl-2 binding potential.
    Kamath PR; Sunil D; Joseph MM; Abdul Salam AA; T T S
    Eur J Med Chem; 2017 Aug; 136():442-451. PubMed ID: 28525842
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, in vitro and in silico evaluation of a new series of oxadiazole-based anticancer agents as potential Akt and FAK inhibitors.
    Altıntop MD; Sever B; Akalın Çiftçi G; Turan-Zitouni G; Kaplancıklı ZA; Özdemir A
    Eur J Med Chem; 2018 Jul; 155():905-924. PubMed ID: 29966916
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and in vitro anticancer activity of novel quinoline and oxadiazole derivatives of ursolic acid.
    Gu W; Jin XY; Li DD; Wang SF; Tao XB; Chen H
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4128-4132. PubMed ID: 28733083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and pro-apoptotic antitumour properties of indole-based 3,5-disubstituted oxadiazoles.
    Ziedan NI; Stefanelli F; Fogli S; Westwell AD
    Eur J Med Chem; 2010 Oct; 45(10):4523-30. PubMed ID: 20705365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of 3-phenyl-N-(2-(3-phenylureido)ethyl)-thiophene-2-sulfonamide compounds as inhibitors of antiapoptotic Bcl-2 family proteins.
    Yang C; Chen S; Zhou M; Li Y; Li Y; Zhang Z; Liu Z; Ba Q; Li J; Wang H; Yan X; Ma D; Wang R
    ChemMedChem; 2014 Jul; 9(7):1436-52. PubMed ID: 24782462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Some new indole-coumarin hybrids; Synthesis, anticancer and Bcl-2 docking studies.
    Kamath PR; Sunil D; Ajees AA; Pai KS; Das S
    Bioorg Chem; 2015 Dec; 63():101-9. PubMed ID: 26469742
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New indenopyrazole linked oxadiazole conjugates as anti-pancreatic cancer agents: Design, synthesis, in silico studies including 3D-QSAR analysis.
    Khan I; Ganapathi T; Rehman MM; Shareef MA; Kumar CG; Kamal A
    Bioorg Med Chem Lett; 2021 Jul; 44():128094. PubMed ID: 33964437
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based design of rhodanine-based acylsulfonamide derivatives as antagonists of the anti-apoptotic Bcl-2 protein.
    Li HQ; Yang J; Ma S; Qiao C
    Bioorg Med Chem; 2012 Jul; 20(14):4194-200. PubMed ID: 22739087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.