566 related articles for article (PubMed ID: 28068329)
1. The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas.
Pemov A; Li H; Patidar R; Hansen NF; Sindiri S; Hartley SW; Wei JS; Elkahloun A; Chandrasekharappa SC; ; Boland JF; Bass S; ; Mullikin JC; Khan J; Widemann BC; Wallace MR; Stewart DR
Oncogene; 2017 Jun; 36(22):3168-3177. PubMed ID: 28068329
[TBL] [Abstract][Full Text] [Related]
2. Low mutation burden and frequent loss of CDKN2A/B and SMARCA2, but not PRC2, define premalignant neurofibromatosis type 1-associated atypical neurofibromas.
Pemov A; Hansen NF; Sindiri S; Patidar R; Higham CS; Dombi E; Miettinen MM; Fetsch P; Brems H; Chandrasekharappa SC; Jones K; Zhu B; Wei JS; ; ; Mullikin JC; Wallace MR; Khan J; Legius E; Widemann BC; Stewart DR
Neuro Oncol; 2019 Aug; 21(8):981-992. PubMed ID: 30722027
[TBL] [Abstract][Full Text] [Related]
3. Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1.
McPherson JR; Ong CK; Ng CC; Rajasegaran V; Heng HL; Yu WS; Tan BK; Madhukumar P; Teo MC; Ngeow J; Thike AA; Rozen SG; Tan PH; Lee AS; Teh BT; Yap YS
Cancer Med; 2015 Dec; 4(12):1871-8. PubMed ID: 26432421
[TBL] [Abstract][Full Text] [Related]
4. Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications.
Gottfried ON; Viskochil DH; Couldwell WT
Neurosurg Focus; 2010 Jan; 28(1):E8. PubMed ID: 20043723
[TBL] [Abstract][Full Text] [Related]
5. Germline and somatic NF1 gene mutations in plexiform neurofibromas.
Upadhyaya M; Spurlock G; Monem B; Thomas N; Friedrich RE; Kluwe L; Mautner V
Hum Mutat; 2008 Aug; 29(8):E103-11. PubMed ID: 18484666
[TBL] [Abstract][Full Text] [Related]
6. Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells.
Ferrer M; Gosline SJC; Stathis M; Zhang X; Guo X; Guha R; Ryman DA; Wallace MR; Kasch-Semenza L; Hao H; Ingersoll R; Mohr D; Thomas C; Verma S; Guinney J; Blakeley JO
Sci Data; 2018 Jun; 5():180106. PubMed ID: 29893754
[TBL] [Abstract][Full Text] [Related]
7. NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors.
Perry A; Roth KA; Banerjee R; Fuller CE; Gutmann DH
Am J Pathol; 2001 Jul; 159(1):57-61. PubMed ID: 11438454
[TBL] [Abstract][Full Text] [Related]
8. NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.
Park HJ; Lee SJ; Sohn YB; Jin HS; Han JH; Kim YB; Yim H; Jeong SY
Int J Oncol; 2013 Feb; 42(2):657-66. PubMed ID: 23292448
[TBL] [Abstract][Full Text] [Related]
9. Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma.
Hirbe AC; Dahiya S; Miller CA; Li T; Fulton RS; Zhang X; McDonald S; DeSchryver K; Duncavage EJ; Walrath J; Reilly KM; Abel HJ; Pekmezci M; Perry A; Ley TJ; Gutmann DH
Clin Cancer Res; 2015 Sep; 21(18):4201-11. PubMed ID: 25925892
[TBL] [Abstract][Full Text] [Related]
10. Comprehensive NF1 screening on cultured Schwann cells from neurofibromas.
Maertens O; Brems H; Vandesompele J; De Raedt T; Heyns I; Rosenbaum T; De Schepper S; De Paepe A; Mortier G; Janssens S; Speleman F; Legius E; Messiaen L
Hum Mutat; 2006 Oct; 27(10):1030-40. PubMed ID: 16941471
[TBL] [Abstract][Full Text] [Related]
11. Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1.
Mund JA; Park S; Smith AE; He Y; Jiang L; Hawley E; Roberson MJ; Mitchell DK; Abu-Sultanah M; Yuan J; Bessler WK; Sandusky G; Chen S; Zhang C; Rhodes SD; Clapp DW
J Biol Chem; 2020 Jul; 295(29):9948-9958. PubMed ID: 32471868
[TBL] [Abstract][Full Text] [Related]
12. Characterization of the somatic mutational spectrum of the neurofibromatosis type 1 (NF1) gene in neurofibromatosis patients with benign and malignant tumors.
Upadhyaya M; Han S; Consoli C; Majounie E; Horan M; Thomas NS; Potts C; Griffiths S; Ruggieri M; von Deimling A; Cooper DN
Hum Mutat; 2004 Feb; 23(2):134-146. PubMed ID: 14722917
[TBL] [Abstract][Full Text] [Related]
13. Concomitant variants in NF1, LZTR1 and GNAZ genes probably contribute to the aggressiveness of plexiform neurofibroma and warrant treatment with MEK inhibitor.
Cohen-Barak E; Toledano-Alhadef H; Danial-Farran N; Livneh I; Mwassi B; Hriesh M; Zagairy F; Gafni-Amsalem C; Bashir H; Khayat M; Warrour N; Sher O; Marom D; Postovsky S; Dujovny T; Ziv M; Shalev SA
Exp Dermatol; 2022 May; 31(5):775-780. PubMed ID: 34913528
[TBL] [Abstract][Full Text] [Related]
14. Reprogramming Captures the Genetic and Tumorigenic Properties of Neurofibromatosis Type 1 Plexiform Neurofibromas.
Carrió M; Mazuelas H; Richaud-Patin Y; Gel B; Terribas E; Rosas I; Jimenez-Delgado S; Biayna J; Vendredy L; Blanco I; Castellanos E; Lázaro C; Raya Á; Serra E
Stem Cell Reports; 2019 Feb; 12(2):411-426. PubMed ID: 30713041
[TBL] [Abstract][Full Text] [Related]
15. Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.
Brossier NM; Carroll SL
Brain Res Bull; 2012 May; 88(1):58-71. PubMed ID: 21855613
[TBL] [Abstract][Full Text] [Related]
16. Somatic NF1 mutational spectrum in benign neurofibromas: mRNA splice defects are common among point mutations.
Serra E; Ars E; Ravella A; Sánchez A; Puig S; Rosenbaum T; Estivill X; Lázaro C
Hum Genet; 2001 May; 108(5):416-29. PubMed ID: 11409870
[TBL] [Abstract][Full Text] [Related]
17. Clonal origin of tumor cells in a plexiform neurofibroma with LOH in NF1 intron 38 and in dermal neurofibromas without LOH of the NF1 gene.
Däschner K; Assum G; Eisenbarth I; Krone W; Hoffmeyer S; Wortmann S; Heymer B; Kehrer-Sawatzki H
Biochem Biophys Res Commun; 1997 May; 234(2):346-50. PubMed ID: 9177273
[TBL] [Abstract][Full Text] [Related]
18. TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions.
Park GH; Lee SJ; Yim H; Han JH; Kim HJ; Sohn YB; Ko JM; Jeong SY
Oncol Rep; 2014 Oct; 32(4):1347-54. PubMed ID: 25109740
[TBL] [Abstract][Full Text] [Related]
19. Confirmation of mutation landscape of NF1-associated malignant peripheral nerve sheath tumors.
Sohier P; Luscan A; Lloyd A; Ashelford K; Laurendeau I; Briand-Suleau A; Vidaud D; Ortonne N; Pasmant E; Upadhyaya M
Genes Chromosomes Cancer; 2017 May; 56(5):421-426. PubMed ID: 28124441
[TBL] [Abstract][Full Text] [Related]
20. NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.
Yu Y; Choi K; Wu J; Andreassen PR; Dexheimer PJ; Keddache M; Brems H; Spinner RJ; Cancelas JA; Martin LJ; Wallace MR; Legius E; Vogel KS; Ratner N
Acta Neuropathol; 2020 Jan; 139(1):157-174. PubMed ID: 31664505
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
