135 related articles for article (PubMed ID: 28081222)
1. AT7867 Inhibits Human Colorectal Cancer Cells via AKT-Dependent and AKT-Independent Mechanisms.
Zhang S; Deng Z; Yao C; Huang P; Zhang Y; Cao S; Li X
PLoS One; 2017; 12(1):e0169585. PubMed ID: 28081222
[TBL] [Abstract][Full Text] [Related]
2. Pre-clinical assessment of A-674563 as an anti-melanoma agent.
Zou Y; Fan G; Wang X
Biochem Biophys Res Commun; 2016 Aug; 477(1):1-8. PubMed ID: 26970307
[TBL] [Abstract][Full Text] [Related]
3. Concurrent targeting Akt and sphingosine kinase 1 by A-674563 in acute myeloid leukemia cells.
Xu L; Zhang Y; Gao M; Wang G; Fu Y
Biochem Biophys Res Commun; 2016 Apr; 472(4):662-8. PubMed ID: 26920060
[TBL] [Abstract][Full Text] [Related]
4. Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo.
Xun C; Chen MB; Qi L; Tie-Ning Z; Peng X; Ning L; Zhi-Xiao C; Li-Wei W
J Exp Clin Cancer Res; 2015 Sep; 34(1):94. PubMed ID: 26337959
[TBL] [Abstract][Full Text] [Related]
5. AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase that induces pharmacodynamic changes and inhibits human tumor xenograft growth.
Grimshaw KM; Hunter LJ; Yap TA; Heaton SP; Walton MI; Woodhead SJ; Fazal L; Reule M; Davies TG; Seavers LC; Lock V; Lyons JF; Thompson NT; Workman P; Garrett MD
Mol Cancer Ther; 2010 May; 9(5):1100-10. PubMed ID: 20423992
[TBL] [Abstract][Full Text] [Related]
6. Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells.
Li JP; Huang ZJ; Lu XS; Zhou YC; Shao Y; He XP; Chen SR; Wang DD; Qin LS; Sun WH
Oncotarget; 2016 Nov; 7(47):77815-77824. PubMed ID: 27780925
[TBL] [Abstract][Full Text] [Related]
7. mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity.
Jin ZZ; Wang W; Fang DL; Jin YJ
Biochem Biophys Res Commun; 2016 Sep; 478(4):1515-20. PubMed ID: 27565731
[TBL] [Abstract][Full Text] [Related]
8. Targeting colorectal cancer cells by a novel sphingosine kinase 1 inhibitor PF-543.
Ju T; Gao D; Fang ZY
Biochem Biophys Res Commun; 2016 Feb; 470(3):728-734. PubMed ID: 26775841
[TBL] [Abstract][Full Text] [Related]
9. The anti-ovarian cancer activity by WYE-132, a mTORC1/2 dual inhibitor.
Zhang D; Xia H; Zhang W; Fang B
Tumour Biol; 2016 Jan; 37(1):1327-36. PubMed ID: 26293898
[TBL] [Abstract][Full Text] [Related]
10. Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.
Ahmad R; Alam M; Hasegawa M; Uchida Y; Al-Obaid O; Kharbanda S; Kufe D
Mol Cancer; 2017 Feb; 16(1):33. PubMed ID: 28153010
[TBL] [Abstract][Full Text] [Related]
11. Preclinical study of cinobufagin as a promising anti-colorectal cancer agent.
Lu XS; Qiao YB; Li Y; Yang B; Chen MB; Xing CG
Oncotarget; 2017 Jan; 8(1):988-998. PubMed ID: 27894091
[TBL] [Abstract][Full Text] [Related]
12. Pre-clinical characterization of 4SC-202, a novel class I HDAC inhibitor, against colorectal cancer cells.
Zhijun H; Shusheng W; Han M; Jianping L; Li-Sen Q; Dechun L
Tumour Biol; 2016 Aug; 37(8):10257-67. PubMed ID: 26831668
[TBL] [Abstract][Full Text] [Related]
13. AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells.
Coant N; García-Barros M; Zhang Q; Obeid LM; Hannun YA
Oncogene; 2018 Jul; 37(28):3852-3863. PubMed ID: 29662189
[TBL] [Abstract][Full Text] [Related]
14. The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121.
Peng Y; Zhou Y; Cheng L; Hu D; Zhou X; Wang Z; Xie C; Zhou F
Biochem Biophys Res Commun; 2015 Sep; 465(1):137-44. PubMed ID: 26235881
[TBL] [Abstract][Full Text] [Related]
15. Targeting sphingosine kinase 1/2 by a novel dual inhibitor SKI-349 suppresses non-small cell lung cancer cell growth.
Xue Y; Jiang K; Ou L; Shen M; Yang Y; Lu J; Xu W
Cell Death Dis; 2022 Jul; 13(7):602. PubMed ID: 35831279
[TBL] [Abstract][Full Text] [Related]
16. Co-administration phenoxodiol with doxorubicin synergistically inhibit the activity of sphingosine kinase-1 (SphK1), a potential oncogene of osteosarcoma, to suppress osteosarcoma cell growth both in vivo and in vitro.
Yao C; Wu S; Li D; Ding H; Wang Z; Yang Y; Yan S; Gu Z
Mol Oncol; 2012 Aug; 6(4):392-404. PubMed ID: 22583777
[TBL] [Abstract][Full Text] [Related]
17. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Shin SW; Seo CY; Han H; Han JY; Jeong JS; Kwak JY; Park JI
Clin Cancer Res; 2009 Sep; 15(17):5414-25. PubMed ID: 19690198
[TBL] [Abstract][Full Text] [Related]
18. Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.
Kim SW; Kim SM; Bae H; Nam D; Lee JH; Lee SG; Shim BS; Kim SH; Ahn KS; Choi SH; Sethi G; Ahn KS
Prostate; 2013 Feb; 73(3):296-305. PubMed ID: 22887478
[TBL] [Abstract][Full Text] [Related]
19. MicroRNA-101 down-regulates sphingosine kinase 1 in colorectal cancer cells.
Chen MB; Yang L; Lu PH; Fu XL; Zhang Y; Zhu YQ; Tian Y
Biochem Biophys Res Commun; 2015 Aug; 463(4):954-60. PubMed ID: 26071354
[TBL] [Abstract][Full Text] [Related]
20. Selective β2-AR Blockage Suppresses Colorectal Cancer Growth Through Regulation of EGFR-Akt/ERK1/2 Signaling, G1-Phase Arrest, and Apoptosis.
Chin CC; Li JM; Lee KF; Huang YC; Wang KC; Lai HC; Cheng CC; Kuo YH; Shi CS
J Cell Physiol; 2016 Feb; 231(2):459-72. PubMed ID: 26189563
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
