256 related articles for article (PubMed ID: 28081256)
1. Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.
Jones JE; Esler WP; Patel R; Lanba A; Vera NB; Pfefferkorn JA; Vernochet C
PLoS One; 2017; 12(1):e0169566. PubMed ID: 28081256
[TBL] [Abstract][Full Text] [Related]
2. Fine-Tuning Lipid Metabolism by Targeting Mitochondria-Associated Acetyl-CoA-Carboxylase 2 in
Valvo V; Iesato A; Kavanagh TR; Priolo C; Zsengeller Z; Pontecorvi A; Stillman IE; Burke SD; Liu X; Nucera C
Thyroid; 2021 Sep; 31(9):1335-1358. PubMed ID: 33107403
[No Abstract] [Full Text] [Related]
3. Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice.
Harada N; Oda Z; Hara Y; Fujinami K; Okawa M; Ohbuchi K; Yonemoto M; Ikeda Y; Ohwaki K; Aragane K; Tamai Y; Kusunoki J
Mol Cell Biol; 2007 Mar; 27(5):1881-8. PubMed ID: 17210641
[TBL] [Abstract][Full Text] [Related]
4. Selective Acetyl-CoA Carboxylase 1 Inhibitor Improves Hepatic Steatosis and Hepatic Fibrosis in a Preclinical Nonalcoholic Steatohepatitis Model.
Tamura YO; Sugama J; Iwasaki S; Sasaki M; Yasuno H; Aoyama K; Watanabe M; Erion DM; Yashiro H
J Pharmacol Exp Ther; 2021 Nov; 379(3):280-289. PubMed ID: 34535562
[TBL] [Abstract][Full Text] [Related]
5. Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.
Luo J; Hong Y; Lu Y; Qiu S; Chaganty BK; Zhang L; Wang X; Li Q; Fan Z
Cancer Lett; 2017 Jan; 384():39-49. PubMed ID: 27693630
[TBL] [Abstract][Full Text] [Related]
6. Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis.
Scott KE; Wheeler FB; Davis AL; Thomas MJ; Ntambi JM; Seals DF; Kridel SJ
PLoS One; 2012; 7(1):e29761. PubMed ID: 22238651
[TBL] [Abstract][Full Text] [Related]
7. Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition.
Esler WP; Tesz GJ; Hellerstein MK; Beysen C; Sivamani R; Turner SM; Watkins SM; Amor PA; Carvajal-Gonzalez S; Geoly FJ; Biddle KE; Purkal JJ; Fitch M; Buckeridge C; Silvia AM; Griffith DA; Gorgoglione M; Hassoun L; Bosanac SS; Vera NB; Rolph TP; Pfefferkorn JA; Sonnenberg GE
Sci Transl Med; 2019 May; 11(492):. PubMed ID: 31092695
[TBL] [Abstract][Full Text] [Related]
8. Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.
Ross TT; Crowley C; Kelly KL; Rinaldi A; Beebe DA; Lech MP; Martinez RV; Carvajal-Gonzalez S; Boucher M; Hirenallur-Shanthappa D; Morin J; Opsahl AC; Vargas SR; Bence KK; Pfefferkorn JA; Esler WP
Cell Mol Gastroenterol Hepatol; 2020; 10(4):829-851. PubMed ID: 32526482
[TBL] [Abstract][Full Text] [Related]
9. Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK.
Gross AS; Zimmermann A; Pendl T; Schroeder S; Schoenlechner H; Knittelfelder O; Lamplmayr L; Santiso A; Aufschnaiter A; Waltenstorfer D; Ortonobes Lara S; Stryeck S; Kast C; Ruckenstuhl C; Hofer SJ; Michelitsch B; Woelflingseder M; Müller R; Carmona-Gutierrez D; Madl T; Büttner S; Fröhlich KU; Shevchenko A; Eisenberg T
J Biol Chem; 2019 Aug; 294(32):12020-12039. PubMed ID: 31209110
[TBL] [Abstract][Full Text] [Related]
10. Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.
Kim CW; Addy C; Kusunoki J; Anderson NN; Deja S; Fu X; Burgess SC; Li C; Ruddy M; Chakravarthy M; Previs S; Milstein S; Fitzgerald K; Kelley DE; Horton JD
Cell Metab; 2017 Aug; 26(2):394-406.e6. PubMed ID: 28768177
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of novel spiro-pentacylamides as acetyl-CoA carboxylase inhibitors.
Wei Q; Mei L; Yang Y; Ma H; Chen H; Zhang H; Zhou J
Bioorg Med Chem; 2018 Aug; 26(14):3866-3874. PubMed ID: 30049586
[TBL] [Abstract][Full Text] [Related]
12. Acetyl-coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double-blind, crossover study.
Stiede K; Miao W; Blanchette HS; Beysen C; Harriman G; Harwood HJ; Kelley H; Kapeller R; Schmalbach T; Westlin WF
Hepatology; 2017 Aug; 66(2):324-334. PubMed ID: 28470676
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of Acetyl-CoA Carboxylase Causes Malformations in Rats and Rabbits: Comparison of Mammalian Findings and Alternative Assays.
Catlin NR; Bowman CJ; Campion SN; Davenport SD; Esler WP; Kumpf SW; Lewis EM; Nowland WS; Ross TT; Stedman DS; Stethem C; Cappon GD
Toxicol Sci; 2021 Jan; 179(2):183-194. PubMed ID: 33247737
[TBL] [Abstract][Full Text] [Related]
14. Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis.
O'Brien AJ; Villani LA; Broadfield LA; Houde VP; Galic S; Blandino G; Kemp BE; Tsakiridis T; Muti P; Steinberg GR
Biochem J; 2015 Jul; 469(2):177-87. PubMed ID: 25940306
[TBL] [Abstract][Full Text] [Related]
15. Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.
Jump DB; Torres-Gonzalez M; Olson LK
Biochem Pharmacol; 2011 Mar; 81(5):649-60. PubMed ID: 21184748
[TBL] [Abstract][Full Text] [Related]
16. Acetyl-CoA carboxylase-a as a novel target for cancer therapy.
Wang C; Rajput S; Watabe K; Liao DF; Cao D
Front Biosci (Schol Ed); 2010 Jan; 2(2):515-26. PubMed ID: 20036965
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.
Svensson RU; Parker SJ; Eichner LJ; Kolar MJ; Wallace M; Brun SN; Lombardo PS; Van Nostrand JL; Hutchins A; Vera L; Gerken L; Greenwood J; Bhat S; Harriman G; Westlin WF; Harwood HJ; Saghatelian A; Kapeller R; Metallo CM; Shaw RJ
Nat Med; 2016 Oct; 22(10):1108-1119. PubMed ID: 27643638
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.
Lally JSV; Ghoshal S; DePeralta DK; Moaven O; Wei L; Masia R; Erstad DJ; Fujiwara N; Leong V; Houde VP; Anagnostopoulos AE; Wang A; Broadfield LA; Ford RJ; Foster RA; Bates J; Sun H; Wang T; Liu H; Ray AS; Saha AK; Greenwood J; Bhat S; Harriman G; Miao W; Rocnik JL; Westlin WF; Muti P; Tsakiridis T; Harwood HJ; Kapeller R; Hoshida Y; Tanabe KK; Steinberg GR; Fuchs BC
Cell Metab; 2019 Jan; 29(1):174-182.e5. PubMed ID: 30244972
[TBL] [Abstract][Full Text] [Related]
19. ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].
Castle JC; Hara Y; Raymond CK; Garrett-Engele P; Ohwaki K; Kan Z; Kusunoki J; Johnson JM
PLoS One; 2009; 4(2):e4369. PubMed ID: 19190759
[TBL] [Abstract][Full Text] [Related]
20. RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells.
Brusselmans K; De Schrijver E; Verhoeven G; Swinnen JV
Cancer Res; 2005 Aug; 65(15):6719-25. PubMed ID: 16061653
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
