256 related articles for article (PubMed ID: 28081256)
21. De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.
Berod L; Friedrich C; Nandan A; Freitag J; Hagemann S; Harmrolfs K; Sandouk A; Hesse C; Castro CN; Bähre H; Tschirner SK; Gorinski N; Gohmert M; Mayer CT; Huehn J; Ponimaskin E; Abraham WR; Müller R; Lochner M; Sparwasser T
Nat Med; 2014 Nov; 20(11):1327-33. PubMed ID: 25282359
[TBL] [Abstract][Full Text] [Related]
22. Acetyl-CoA carboxylase inhibitors attenuate WNT and Hedgehog signaling and suppress pancreatic tumor growth.
Petrova E; Scholz A; Paul J; Sturz A; Haike K; Siegel F; Mumberg D; Liu N
Oncotarget; 2017 Jul; 8(30):48660-48670. PubMed ID: 27750213
[TBL] [Abstract][Full Text] [Related]
23. Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.
Savage DB; Choi CS; Samuel VT; Liu ZX; Zhang D; Wang A; Zhang XM; Cline GW; Yu XX; Geisler JG; Bhanot S; Monia BP; Shulman GI
J Clin Invest; 2006 Mar; 116(3):817-24. PubMed ID: 16485039
[TBL] [Abstract][Full Text] [Related]
24. Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.
Stoiber K; Nagło O; Pernpeintner C; Zhang S; Koeberle A; Ulrich M; Werz O; Müller R; Zahler S; Lohmüller T; Feldmann J; Braig S
Br J Cancer; 2018 Jan; 118(1):43-51. PubMed ID: 29112683
[TBL] [Abstract][Full Text] [Related]
25. Expression, purification, and characterization of human acetyl-CoA carboxylase 2.
Kim KW; Yamane H; Zondlo J; Busby J; Wang M
Protein Expr Purif; 2007 May; 53(1):16-23. PubMed ID: 17223360
[TBL] [Abstract][Full Text] [Related]
26. Acetyl-CoA carboxylase inhibition for the treatment of metabolic syndrome.
Harwood HJ
Curr Opin Investig Drugs; 2004 Mar; 5(3):283-9. PubMed ID: 15083594
[TBL] [Abstract][Full Text] [Related]
27. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors.
Wei Q; Mei L; Chen P; Yuan X; Zhang H; Zhou J
Bioorg Chem; 2020 Aug; 101():103943. PubMed ID: 32554277
[TBL] [Abstract][Full Text] [Related]
28. Spirolactam-based acetyl-CoA carboxylase inhibitors: toward improved metabolic stability of a chromanone lead structure.
Griffith DA; Dow RL; Huard K; Edmonds DJ; Bagley SW; Polivkova J; Zeng D; Garcia-Irizarry CN; Southers JA; Esler W; Amor P; Loomis K; McPherson K; Bahnck KB; Préville C; Banks T; Moore DE; Mathiowetz AM; Menhaji-Klotz E; Smith AC; Doran SD; Beebe DA; Dunn MF
J Med Chem; 2013 Sep; 56(17):7110-9. PubMed ID: 23981033
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors.
Li EQ; Zhao W; Zhang C; Qin LZ; Liu SJ; Feng ZQ; Wen X; Chen CP
Eur J Pharm Sci; 2019 Sep; 137():105010. PubMed ID: 31325544
[TBL] [Abstract][Full Text] [Related]
30. Diminishing acetyl-CoA carboxylase 1 attenuates CCA migration via AMPK-NF-κB-snail axis.
Saisomboon S; Kariya R; Boonnate P; Sawanyawisuth K; Cha'on U; Luvira V; Chamgramol Y; Pairojkul C; Seubwai W; Silsirivanit A; Wongkham S; Okada S; Jitrapakdee S; Vaeteewoottacharn K
Biochim Biophys Acta Mol Basis Dis; 2023 Jun; 1869(5):166694. PubMed ID: 36972768
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors.
Gu YG; Weitzberg M; Clark RF; Xu X; Li Q; Zhang T; Hansen TM; Liu G; Xin Z; Wang X; Wang R; McNally T; Zinker BA; Frevert EU; Camp HS; Beutel BA; Sham HL
J Med Chem; 2006 Jun; 49(13):3770-3. PubMed ID: 16789734
[TBL] [Abstract][Full Text] [Related]
32. Discovery of N-(1-(3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl)ethyl)acetamides as novel acetyl-CoA carboxylase 2 (ACC2) inhibitors with peroxisome proliferator-activated receptor α/δ (PPARα/δ) dual agonistic activity.
Okazaki S; Noguchi-Yachide T; Sakai T; Ishikawa M; Makishima M; Hashimoto Y; Yamaguchi T
Bioorg Med Chem; 2016 Nov; 24(21):5258-5269. PubMed ID: 27591006
[TBL] [Abstract][Full Text] [Related]
33. Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.
Huard K; Smith AC; Cappon G; Dow RL; Edmonds DJ; El-Kattan A; Esler WP; Fernando DP; Griffith DA; Kalgutkar AS; Ross TT; Bagley SW; Beebe D; Bi YA; Cabral S; Crowley C; Doran SD; Dowling MS; Liras S; Mascitti V; Niosi M; Pfefferkorn JA; Polivkova J; Préville C; Price DA; Shavnya A; Shirai N; Smith AH; Southers JR; Tess DA; Thuma BA; Varma MV; Yang X
J Med Chem; 2020 Oct; 63(19):10879-10896. PubMed ID: 32809824
[TBL] [Abstract][Full Text] [Related]
34. Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.
Corominas-Faja B; Cuyàs E; Gumuzio J; Bosch-Barrera J; Leis O; Martin ÁG; Menendez JA
Oncotarget; 2014 Sep; 5(18):8306-16. PubMed ID: 25246709
[TBL] [Abstract][Full Text] [Related]
35. Oncolytic avian reovirus σA-modulated fatty acid metabolism through the PSMB6/Akt/SREBP1/acetyl-CoA carboxylase pathway to increase energy production for virus replication.
Hsu CY; Chen YH; Huang WR; Huang JW; Chen IC; Chang YK; Wang CY; Chang CD; Liao TL; Nielsen BL; Liu HJ
Vet Microbiol; 2022 Oct; 273():109545. PubMed ID: 35998542
[TBL] [Abstract][Full Text] [Related]
36. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal.
Abu-Elheiga L; Matzuk MM; Kordari P; Oh W; Shaikenov T; Gu Z; Wakil SJ
Proc Natl Acad Sci U S A; 2005 Aug; 102(34):12011-6. PubMed ID: 16103361
[TBL] [Abstract][Full Text] [Related]
37. Blood meal drives de novo lipogenesis in the fat body of Rhodnius prolixus.
Saraiva FB; Alves-Bezerra M; Majerowicz D; Paes-Vieira L; Braz V; Almeida MGMD; Meyer-Fernandes JR; Gondim KC
Insect Biochem Mol Biol; 2021 Jun; 133():103511. PubMed ID: 33278628
[TBL] [Abstract][Full Text] [Related]
38. Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes.
Griffith DA; Kung DW; Esler WP; Amor PA; Bagley SW; Beysen C; Carvajal-Gonzalez S; Doran SD; Limberakis C; Mathiowetz AM; McPherson K; Price DA; Ravussin E; Sonnenberg GE; Southers JA; Sweet LJ; Turner SM; Vajdos FF
J Med Chem; 2014 Dec; 57(24):10512-26. PubMed ID: 25423286
[TBL] [Abstract][Full Text] [Related]
39. Acetyl-CoA Carboxylase Inhibitor CP640.186 Increases Tubulin Acetylation and Impairs Thrombin-Induced Platelet Aggregation.
Octave M; Pirotton L; Ginion A; Robaux V; Lepropre S; Ambroise J; Bouzin C; Guigas B; Giera M; Foretz M; Bertrand L; Beauloye C; Horman S
Int J Mol Sci; 2021 Dec; 22(23):. PubMed ID: 34884932
[TBL] [Abstract][Full Text] [Related]
40. Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis.
Ma J; Duan W; Han S; Lei J; Xu Q; Chen X; Jiang Z; Nan L; Li J; Chen K; Han L; Wang Z; Li X; Wu E; Huo X
Oncotarget; 2015 Aug; 6(25):20993-1003. PubMed ID: 25895130
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]