323 related articles for article (PubMed ID: 28082183)
1. Effects of P2X7 receptor antagonists on hypoxia-induced neonatal seizures in mice.
Rodriguez-Alvarez N; Jimenez-Mateos EM; Engel T; Quinlan S; Reschke CR; Conroy RM; Bhattacharya A; Boylan GB; Henshall DC
Neuropharmacology; 2017 Apr; 116():351-363. PubMed ID: 28082183
[TBL] [Abstract][Full Text] [Related]
2. Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.
Jimenez-Pacheco A; Mesuret G; Sanz-Rodriguez A; Tanaka K; Mooney C; Conroy R; Miras-Portugal MT; Diaz-Hernandez M; Henshall DC; Engel T
Epilepsia; 2013 Sep; 54(9):1551-61. PubMed ID: 23808395
[TBL] [Abstract][Full Text] [Related]
3. Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy.
Jimenez-Pacheco A; Diaz-Hernandez M; Arribas-Blázquez M; Sanz-Rodriguez A; Olivos-Oré LA; Artalejo AR; Alves M; Letavic M; Miras-Portugal MT; Conroy RM; Delanty N; Farrell MA; O'Brien DF; Bhattacharya A; Engel T; Henshall DC
J Neurosci; 2016 Jun; 36(22):5920-32. PubMed ID: 27251615
[TBL] [Abstract][Full Text] [Related]
4. Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice.
Engel T; Gomez-Villafuertes R; Tanaka K; Mesuret G; Sanz-Rodriguez A; Garcia-Huerta P; Miras-Portugal MT; Henshall DC; Diaz-Hernandez M
FASEB J; 2012 Apr; 26(4):1616-28. PubMed ID: 22198387
[TBL] [Abstract][Full Text] [Related]
5. The P2X7 receptor contributes to seizures and inflammation-driven long-lasting brain hyperexcitability following hypoxia in neonatal mice.
Smith J; Menéndez Méndez A; Alves M; Parras A; Conte G; Bhattacharya A; Ceusters M; Nicke A; Henshall DC; Jimenez-Mateos EM; Engel T
Br J Pharmacol; 2023 Jul; 180(13):1710-1729. PubMed ID: 36637008
[TBL] [Abstract][Full Text] [Related]
6. Effects of hypoxia-induced neonatal seizures on acute hippocampal injury and later-life seizure susceptibility and anxiety-related behavior in mice.
Rodriguez-Alvarez N; Jimenez-Mateos EM; Dunleavy M; Waddington JL; Boylan GB; Henshall DC
Neurobiol Dis; 2015 Nov; 83():100-14. PubMed ID: 26341542
[TBL] [Abstract][Full Text] [Related]
7. Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors.
Yue N; Huang H; Zhu X; Han Q; Wang Y; Li B; Liu Q; Wu G; Zhang Y; Yu J
J Neuroinflammation; 2017 May; 14(1):102. PubMed ID: 28486969
[TBL] [Abstract][Full Text] [Related]
8. MiR-187-3p mimic alleviates ischemia-reperfusion-induced pain hypersensitivity through inhibiting spinal P2X7R and subsequent mature IL-1β release in mice.
Li XQ; Yu Q; Zhang ZL; Sun XJ; Ma H
Brain Behav Immun; 2019 Jul; 79():91-101. PubMed ID: 31100367
[TBL] [Abstract][Full Text] [Related]
9. Chronic administration of P2X7 receptor antagonist JNJ-47965567 delays disease onset and progression, and improves motor performance in ALS SOD1
Ruiz-Ruiz C; García-Magro N; Negredo P; Avendaño C; Bhattacharya A; Ceusters M; García AG
Dis Model Mech; 2020 Oct; 13(10):. PubMed ID: 33174532
[TBL] [Abstract][Full Text] [Related]
10. P2X7 receptor antagonism prevents IL-1β release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy.
Khalafalla MG; Woods LT; Camden JM; Khan AA; Limesand KH; Petris MJ; Erb L; Weisman GA
J Biol Chem; 2017 Oct; 292(40):16626-16637. PubMed ID: 28798231
[TBL] [Abstract][Full Text] [Related]
11. P2X7 receptor inhibition protects against ischemic acute kidney injury in mice.
Yan Y; Bai J; Zhou X; Tang J; Jiang C; Tolbert E; Bayliss G; Gong R; Zhao TC; Zhuang S
Am J Physiol Cell Physiol; 2015 Mar; 308(6):C463-72. PubMed ID: 25588875
[TBL] [Abstract][Full Text] [Related]
12. Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures.
Quinlan SMM; Rodriguez-Alvarez N; Molloy EJ; Madden SF; Boylan GB; Henshall DC; Jimenez-Mateos EM
Sci Rep; 2018 Jul; 8(1):9986. PubMed ID: 29968748
[TBL] [Abstract][Full Text] [Related]
13. P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage.
Mesuret G; Engel T; Hessel EV; Sanz-Rodriguez A; Jimenez-Pacheco A; Miras-Portugal MT; Diaz-Hernandez M; Henshall DC
CNS Neurosci Ther; 2014 Jun; 20(6):556-64. PubMed ID: 24750893
[TBL] [Abstract][Full Text] [Related]
14. P2X7 receptor blockade protects against cisplatin-induced nephrotoxicity in mice by decreasing the activities of inflammasome components, oxidative stress and caspase-3.
Zhang Y; Yuan F; Cao X; Zhai Z; GangHuang ; Du X; Wang Y; Zhang J; Huang Y; Zhao J; Hou W
Toxicol Appl Pharmacol; 2014 Nov; 281(1):1-10. PubMed ID: 25308879
[TBL] [Abstract][Full Text] [Related]
15. P2X7 receptor antagonism reduces the severity of spontaneous seizures in a chronic model of temporal lobe epilepsy.
Amhaoul H; Ali I; Mola M; Van Eetveldt A; Szewczyk K; Missault S; Bielen K; Kumar-Singh S; Rech J; Lord B; Ceusters M; Bhattacharya A; Dedeurwaerdere S
Neuropharmacology; 2016 Jun; 105():175-185. PubMed ID: 26775823
[TBL] [Abstract][Full Text] [Related]
16. P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis.
da Silva GL; Sperotto ND; Borges TJ; Bonorino C; Takyia CM; Coutinho-Silva R; Campos MM; Zanin RF; Morrone FB
Exp Dermatol; 2013 Mar; 22(3):184-8. PubMed ID: 23489421
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.
Bhattacharya A; Wang Q; Ao H; Shoblock JR; Lord B; Aluisio L; Fraser I; Nepomuceno D; Neff RA; Welty N; Lovenberg TW; Bonaventure P; Wickenden AD; Letavic MA
Br J Pharmacol; 2013 Oct; 170(3):624-40. PubMed ID: 23889535
[TBL] [Abstract][Full Text] [Related]
18. Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models.
Fischer W; Franke H; Krügel U; Müller H; Dinkel K; Lord B; Letavic MA; Henshall DC; Engel T
PLoS One; 2016; 11(6):e0156468. PubMed ID: 27281030
[TBL] [Abstract][Full Text] [Related]
19. Ca(2+) spiking activity caused by the activation of store-operated Ca(2+) channels mediates TNF-α release from microglial cells under chronic purinergic stimulation.
Ikeda M; Tsuno S; Sugiyama T; Hashimoto A; Yamoto K; Takeuchi K; Kishi H; Mizuguchi H; Kohsaka SI; Yoshioka T
Biochim Biophys Acta; 2013 Dec; 1833(12):2573-2585. PubMed ID: 23830920
[TBL] [Abstract][Full Text] [Related]
20. The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells.
Giannuzzo A; Pedersen SF; Novak I
Mol Cancer; 2015 Nov; 14():203. PubMed ID: 26607222
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
