These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
237 related articles for article (PubMed ID: 28084422)
1. Targeting pathogen metabolism without collateral damage to the host. Haanstra JR; Gerding A; Dolga AM; Sorgdrager FJH; Buist-Homan M; du Toit F; Faber KN; Holzhütter HG; Szöör B; Matthews KR; Snoep JL; Westerhoff HV; Bakker BM Sci Rep; 2017 Jan; 7():40406. PubMed ID: 28084422 [TBL] [Abstract][Full Text] [Related]
2. Chemotherapeutic strategies against Trypanosoma brucei: drug targets vs. drug targeting. Lüscher A; de Koning HP; Mäser P Curr Pharm Des; 2007; 13(6):555-67. PubMed ID: 17346174 [TBL] [Abstract][Full Text] [Related]
3. Genetic validation of aldolase and glyceraldehyde-3-phosphate dehydrogenase as drug targets in Trypanosoma brucei. Cáceres AJ; Michels PA; Hannaert V Mol Biochem Parasitol; 2010 Jan; 169(1):50-4. PubMed ID: 19748525 [TBL] [Abstract][Full Text] [Related]
4. Prospects for antiparasitic drugs. The case of Trypanosoma brucei, the causative agent of African sleeping sickness. Eisenthal R; Cornish-Bowden A J Biol Chem; 1998 Mar; 273(10):5500-5. PubMed ID: 9488673 [TBL] [Abstract][Full Text] [Related]
5. [Rational concepts and the study of active molecules against various trypanosomiases]. Périé J; de Albuquerque C; Blonski C; Chauvière G; Gefflaut T; Page P; Trinquier M; Willson M Bull Soc Pathol Exot; 1994; 87(5):353-61. PubMed ID: 7496200 [TBL] [Abstract][Full Text] [Related]
6. Inhibition of glyceraldehyde-3-phosphate dehydrogenase by pentalenolactone in Trypanosoma brucei. Duszenko M; Mecke D Mol Biochem Parasitol; 1986 Jun; 19(3):223-9. PubMed ID: 3736593 [TBL] [Abstract][Full Text] [Related]
7. Antiparasitic agents: new drugs on the horizon. Mäser P; Wittlin S; Rottmann M; Wenzler T; Kaiser M; Brun R Curr Opin Pharmacol; 2012 Oct; 12(5):562-6. PubMed ID: 22652215 [TBL] [Abstract][Full Text] [Related]
8. Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs. Bakker BM; Westerhoff HV; Opperdoes FR; Michels PA Mol Biochem Parasitol; 2000 Feb; 106(1):1-10. PubMed ID: 10743606 [TBL] [Abstract][Full Text] [Related]
10. Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based design: toward new drugs for the treatment of sleeping sickness. Verlinde CL; Callens M; Van Calenbergh S; Van Aerschot A; Herdewijn P; Hannaert V; Michels PA; Opperdoes FR; Hol WG J Med Chem; 1994 Oct; 37(21):3605-13. PubMed ID: 7932587 [TBL] [Abstract][Full Text] [Related]
12. Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds. Bilsland E; Sparkes A; Williams K; Moss HJ; de Clare M; Pir P; Rowland J; Aubrey W; Pateman R; Young M; Carrington M; King RD; Oliver SG Open Biol; 2013 Feb; 3(2):120158. PubMed ID: 23446112 [TBL] [Abstract][Full Text] [Related]
13. Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi. Belluti F; Uliassi E; Veronesi G; Bergamini C; Kaiser M; Brun R; Viola A; Fato R; Michels PA; Krauth-Siegel RL; Cavalli A; Bolognesi ML ChemMedChem; 2014 Feb; 9(2):371-82. PubMed ID: 24403089 [TBL] [Abstract][Full Text] [Related]
14. Trypanosoma brucei: host parasite interaction in parasite destruction by salicylhydroxamic acid and glycerol in mice. Amole BO; Clarkson AB Exp Parasitol; 1981 Feb; 51(1):133-40. PubMed ID: 6109641 [No Abstract] [Full Text] [Related]
15. Activity of Aromathecins against African Trypanosomes. Nenortas NP; Cinelli MA; Morrell AE; Cushman M; Shapiro TA Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30104277 [TBL] [Abstract][Full Text] [Related]
16. Sleeping sickness pathogen (Trypanosoma brucei) and natural products: therapeutic targets and screening systems. Hannaert V Planta Med; 2011 Apr; 77(6):586-97. PubMed ID: 20945274 [TBL] [Abstract][Full Text] [Related]
17. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro. Ferrigno F; Biancofiore I; Malancona S; Ponzi S; Paonessa G; Graziani R; Bresciani A; Gennari N; Di Marco A; Kaiser M; Summa V; Harper S; Ontoria JM Bioorg Med Chem Lett; 2018 Dec; 28(23-24):3689-3692. PubMed ID: 30482621 [TBL] [Abstract][Full Text] [Related]
19. Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase. Aronov AM; Suresh S; Buckner FS; Van Voorhis WC; Verlinde CL; Opperdoes FR; Hol WG; Gelb MH Proc Natl Acad Sci U S A; 1999 Apr; 96(8):4273-8. PubMed ID: 10200252 [TBL] [Abstract][Full Text] [Related]
20. Overview of the role of kinetoplastid surface carbohydrates in infection and host cell invasion: prospects for therapeutic intervention. Valente M; Castillo-Acosta VM; Vidal AE; González-Pacanowska D Parasitology; 2019 Dec; 146(14):1743-1754. PubMed ID: 31603063 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]