BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 28090088)

  • 1. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor.
    Xu J; Zhou W; Yang F; Chen G; Li H; Zhao Y; Liu P; Li H; Tan M; Xiong X; Sun Y
    Nat Commun; 2017 Jan; 8():14002. PubMed ID: 28090088
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FBXW2 suppresses migration and invasion of lung cancer cells via promoting β-catenin ubiquitylation and degradation.
    Yang F; Xu J; Li H; Tan M; Xiong X; Sun Y
    Nat Commun; 2019 Mar; 10(1):1382. PubMed ID: 30918250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent.
    Wei S; Chu PC; Chuang HC; Hung WC; Kulp SK; Chen CS
    PLoS One; 2012; 7(10):e47298. PubMed ID: 23071779
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells.
    Yin Y; Xie CM; Li H; Tan M; Chen G; Schiff R; Xiong X; Sun Y
    Proc Natl Acad Sci U S A; 2019 Oct; 116(41):20528-20538. PubMed ID: 31548378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FBXW2 suppresses proliferation and invasion of lung cancer cells by targeting SKP2 and β-catenin.
    Yang F; Sun Y
    Mol Cell Oncol; 2019; 6(4):1607458. PubMed ID: 31211237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
    Zhou T; Chen T; Lai B; Zhang W; Luo X; Xia D; Fu W; Xu J
    Cell Mol Life Sci; 2022 May; 79(5):268. PubMed ID: 35499593
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated receptor gamma.
    Wei S; Lin LF; Yang CC; Wang YC; Chang GD; Chen H; Chen CS
    Mol Pharmacol; 2007 Sep; 72(3):725-33. PubMed ID: 17569795
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis.
    Barik GK; Sahay O; Mukhopadhyay A; Manne RK; Islam S; Roy A; Nath S; Santra MK
    Cell Death Dis; 2023 Sep; 14(9):623. PubMed ID: 37736741
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of lung cancer cell growth and invasiveness by beta-TRCP.
    He N; Li C; Zhang X; Sheng T; Chi S; Chen K; Wang Q; Vertrees R; Logrono R; Xie J
    Mol Carcinog; 2005 Jan; 42(1):18-28. PubMed ID: 15536641
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR.
    Kainulainen M; Lau S; Samuel CE; Hornung V; Weber F
    J Virol; 2016 Jul; 90(13):6140-7. PubMed ID: 27122577
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells.
    Wei S; Yang HC; Chuang HC; Yang J; Kulp SK; Lu PJ; Lai MD; Chen CS
    J Biol Chem; 2008 Sep; 283(39):26759-70. PubMed ID: 18650423
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The characteristics and roles of β-TrCP1/2 in carcinogenesis.
    Bi Y; Cui D; Xiong X; Zhao Y
    FEBS J; 2021 Jun; 288(11):3351-3374. PubMed ID: 33021036
    [TBL] [Abstract][Full Text] [Related]  

  • 13. β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells.
    Yi YW; Kang HJ; Bae EJ; Oh S; Seong YS; Bae I
    Exp Mol Med; 2015 Feb; 47(2):e143. PubMed ID: 25721419
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeted degradation of beta-catenin by chimeric F-box fusion proteins.
    Liu J; Stevens J; Matsunami N; White RL
    Biochem Biophys Res Commun; 2004 Jan; 313(4):1023-9. PubMed ID: 14706645
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth.
    Cui D; Dai X; Shu J; Ma Y; Wei D; Xiong X; Zhao Y
    Cell Death Differ; 2020 Mar; 27(3):1119-1133. PubMed ID: 31406304
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of SCF
    Yamashita M; Owa T; Shiraishi R; Adachi T; Ichijo K; Taya S; Miyashita S; Hoshino M
    Genes Cells; 2020 Dec; 25(12):796-810. PubMed ID: 33020978
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Early mitotic inhibitor-1, an anaphase-promoting complex/cyclosome inhibitor, can control tumor cell proliferation in hepatocellular carcinoma: correlation with Skp2 stability and degradation of p27(Kip1).
    Zhao Y; Tang Q; Ni R; Huang X; Wang Y; Lu C; Shen A; Wang Y; Li C; Yuan Q; Chen H; Cheng C; He S
    Hum Pathol; 2013 Mar; 44(3):365-73. PubMed ID: 22995332
    [TBL] [Abstract][Full Text] [Related]  

  • 18. USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates.
    Zhang F; Zhao Y; Sun Y
    J Biol Chem; 2021 Oct; 297(4):101109. PubMed ID: 34425107
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ubiquitin E3 ligase SCF(β-TRCP) regulates TRIB2 stability in liver cancer cells.
    Qiao Y; Zhang Y; Wang J
    Biochem Biophys Res Commun; 2013 Nov; 441(3):555-9. PubMed ID: 24211582
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recent advances in SCF ubiquitin ligase complex: Clinical implications.
    Zheng N; Zhou Q; Wang Z; Wei W
    Biochim Biophys Acta; 2016 Aug; 1866(1):12-22. PubMed ID: 27156687
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.