249 related articles for article (PubMed ID: 28094766)
1. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis.
Wu CJ; Feng X; Lu M; Morimura S; Udey MC
J Clin Invest; 2017 Feb; 127(2):623-634. PubMed ID: 28094766
[TBL] [Abstract][Full Text] [Related]
2. Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins.
Wu CJ; Lu M; Feng X; Nakato G; Udey MC
Cells; 2020 Apr; 9(4):. PubMed ID: 32326212
[TBL] [Abstract][Full Text] [Related]
3. Matriptase drives early-onset intestinal failure in a mouse model of congenital tufting enteropathy.
Szabo R; Callies LK; Bugge TH
Development; 2019 Nov; 146(22):. PubMed ID: 31628112
[TBL] [Abstract][Full Text] [Related]
4. Early-onset tufting enteropathy in HAI-2-deficient mice is independent of matriptase-mediated cleavage of EpCAM.
Szabo R; Kawaguchi M; Kataoka H; Bugge TH
Development; 2023 Sep; 150(17):. PubMed ID: 37539662
[TBL] [Abstract][Full Text] [Related]
5. Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.
Kawaguchi M; Yamamoto K; Takeda N; Fukushima T; Yamashita F; Sato K; Kitamura K; Hippo Y; Janetka JW; Kataoka H
Commun Biol; 2019; 2():11. PubMed ID: 30623107
[TBL] [Abstract][Full Text] [Related]
6. The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin.
Friis S; Sales KU; Schafer JM; Vogel LK; Kataoka H; Bugge TH
J Biol Chem; 2014 Aug; 289(32):22319-32. PubMed ID: 24962579
[TBL] [Abstract][Full Text] [Related]
7. Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.
Buzza MS; Netzel-Arnett S; Shea-Donohue T; Zhao A; Lin CY; List K; Szabo R; Fasano A; Bugge TH; Antalis TM
Proc Natl Acad Sci U S A; 2010 Mar; 107(9):4200-5. PubMed ID: 20142489
[TBL] [Abstract][Full Text] [Related]
8. Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy.
Szabo R; Bugge TH
PLoS One; 2018; 13(4):e0194660. PubMed ID: 29617460
[TBL] [Abstract][Full Text] [Related]
9. Enteroids expressing a disease-associated mutant of EpCAM are a model for congenital tufting enteropathy.
Das B; Okamoto K; Rabalais J; Kozan PA; Marchelletta RR; McGeough MD; Durali N; Go M; Barrett KE; Das S; Sivagnanam M
Am J Physiol Gastrointest Liver Physiol; 2019 Nov; 317(5):G580-G591. PubMed ID: 31433211
[TBL] [Abstract][Full Text] [Related]
10. Functional consequences of EpCam mutation in mice and men.
Mueller JL; McGeough MD; Peña CA; Sivagnanam M
Am J Physiol Gastrointest Liver Physiol; 2014 Feb; 306(4):G278-88. PubMed ID: 24337010
[TBL] [Abstract][Full Text] [Related]
11. EpCAM (CD326) Regulates Intestinal Epithelial Integrity and Stem Cells via Rho-Associated Kinase.
Ouchi T; Morimura S; Dow LE; Miyoshi H; Udey MC
Cells; 2021 Jan; 10(2):. PubMed ID: 33525555
[TBL] [Abstract][Full Text] [Related]
12. EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins.
Lei Z; Maeda T; Tamura A; Nakamura T; Yamazaki Y; Shiratori H; Yashiro K; Tsukita S; Hamada H
Dev Biol; 2012 Nov; 371(2):136-45. PubMed ID: 22819673
[TBL] [Abstract][Full Text] [Related]
13. Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions.
Wu CJ; Mannan P; Lu M; Udey MC
J Biol Chem; 2013 Apr; 288(17):12253-68. PubMed ID: 23486470
[TBL] [Abstract][Full Text] [Related]
14. EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice.
Szabo R; Ward JM; Artunc F; Bugge TH
Biol Open; 2022 Jul; 11(7):. PubMed ID: 35730316
[TBL] [Abstract][Full Text] [Related]
15. SPINT2 (HAI-2) missense variants identified in congenital sodium diarrhea/tufting enteropathy affect the ability of HAI-2 to inhibit prostasin but not matriptase.
Holt-Danborg L; Vodopiutz J; Nonboe AW; De Laffolie J; Skovbjerg S; Wolters VM; Müller T; Hetzer B; Querfurt A; Zimmer KP; Jensen JK; Entenmann A; Heinz-Erian P; Vogel LK; Janecke AR
Hum Mol Genet; 2019 Mar; 28(5):828-841. PubMed ID: 30445423
[TBL] [Abstract][Full Text] [Related]
16. Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2.
Shiao F; Liu LO; Huang N; Lai YJ; Barndt RJ; Tseng CC; Wang JK; Jia B; Johnson MD; Lin CY
PLoS One; 2017; 12(1):e0170944. PubMed ID: 28125689
[TBL] [Abstract][Full Text] [Related]
17. Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells.
Chang HH; Xu Y; Lai H; Yang X; Tseng CC; Lai YJ; Pan Y; Zhou E; Johnson MD; Wang JK; Lin CY
PLoS One; 2015; 10(3):e0120489. PubMed ID: 25786220
[TBL] [Abstract][Full Text] [Related]
18. Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation.
Szabo R; Uzzun Sales K; Kosa P; Shylo NA; Godiksen S; Hansen KK; Friis S; Gutkind JS; Vogel LK; Hummler E; Camerer E; Bugge TH
PLoS Genet; 2012; 8(8):e1002937. PubMed ID: 22952456
[TBL] [Abstract][Full Text] [Related]
19. Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy.
Das B; Okamoto K; Rabalais J; Young JA; Barrett KE; Sivagnanam M
Cell Mol Gastroenterol Hepatol; 2021; 12(4):1353-1371. PubMed ID: 34198013
[TBL] [Abstract][Full Text] [Related]
20. HAI-2 stabilizes, inhibits and regulates SEA-cleavage-dependent secretory transport of matriptase.
Nonboe AW; Krigslund O; Soendergaard C; Skovbjerg S; Friis S; Andersen MN; Ellis V; Kawaguchi M; Kataoka H; Bugge TH; Vogel LK
Traffic; 2017 Jun; 18(6):378-391. PubMed ID: 28371047
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
