These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 28104464)

  • 1. Genetic defects in PI3Kδ affect B-cell differentiation and maturation leading to hypogammaglobulineamia and recurrent infections.
    Wentink M; Dalm V; Lankester AC; van Schouwenburg PA; Schölvinck L; Kalina T; Zachova R; Sediva A; Lambeck A; Pico-Knijnenburg I; van Dongen JJ; Pac M; Bernatowska E; van Hagen M; Driessen G; van der Burg M
    Clin Immunol; 2017 Mar; 176():77-86. PubMed ID: 28104464
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced AKT Phosphorylation of Circulating B Cells in Patients With Activated PI3Kδ Syndrome.
    Asano T; Okada S; Tsumura M; Yeh TW; Mitsui-Sekinaka K; Tsujita Y; Ichinose Y; Shimada A; Hashimoto K; Wada T; Imai K; Ohara O; Morio T; Nonoyama S; Kobayashi M
    Front Immunol; 2018; 9():568. PubMed ID: 29675019
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A single center experience on PI3K/AKT/MTOR signaling defects: Towards pathogenicity assessment for four novel defects.
    Bildik HN; Esenboga S; Halaclı SO; Karaatmaca B; Aytekin ES; Nabiyeva N; Akarsu A; Ocak M; Erman B; Tan C; Arikoglu T; Yaz I; Cicek B; Tezcan I; Cagdas D
    Pediatr Allergy Immunol; 2024 Sep; 35(9):e14245. PubMed ID: 39312287
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of B-cell intracellular signaling by monitoring the PI3K-Akt axis in patients with common variable immunodeficiency and activated phosphoinositide 3-kinase delta syndrome.
    Del Pino-Molina L; Torres Canizales JM; Rodríguez-Pena R; López-Granados E
    Cytometry B Clin Cytom; 2021 Jul; 100(4):460-466. PubMed ID: 32961022
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphatase and tensin homolog (PTEN) mutation can cause activated phosphatidylinositol 3-kinase δ syndrome-like immunodeficiency.
    Tsujita Y; Mitsui-Sekinaka K; Imai K; Yeh TW; Mitsuiki N; Asano T; Ohnishi H; Kato Z; Sekinaka Y; Zaha K; Kato T; Okano T; Takashima T; Kobayashi K; Kimura M; Kunitsu T; Maruo Y; Kanegane H; Takagi M; Yoshida K; Okuno Y; Muramatsu H; Shiraishi Y; Chiba K; Tanaka H; Miyano S; Kojima S; Ogawa S; Ohara O; Okada S; Kobayashi M; Morio T; Nonoyama S
    J Allergy Clin Immunol; 2016 Dec; 138(6):1672-1680.e10. PubMed ID: 27426521
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Class-Switch Recombination (CSR)/Hyper-IgM (HIGM) Syndromes and Phosphoinositide 3-Kinase (PI3K) Defects.
    Jhamnani RD; Nunes-Santos CJ; Bergerson J; Rosenzweig SD
    Front Immunol; 2018; 9():2172. PubMed ID: 30319630
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Germline-activating mutations in
    Avery DT; Kane A; Nguyen T; Lau A; Nguyen A; Lenthall H; Payne K; Shi W; Brigden H; French E; Bier J; Hermes JR; Zahra D; Sewell WA; Butt D; Elliott M; Boztug K; Meyts I; Choo S; Hsu P; Wong M; Berglund LJ; Gray P; O'Sullivan M; Cole T; Holland SM; Ma CS; Burkhart C; Corcoran LM; Phan TG; Brink R; Uzel G; Deenick EK; Tangye SG
    J Exp Med; 2018 Aug; 215(8):2073-2095. PubMed ID: 30018075
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activating PI3Kδ mutations in a cohort of 669 patients with primary immunodeficiency.
    Elgizouli M; Lowe DM; Speckmann C; Schubert D; Hülsdünker J; Eskandarian Z; Dudek A; Schmitt-Graeff A; Wanders J; Jørgensen SF; Fevang B; Salzer U; Nieters A; Burns S; Grimbacher B
    Clin Exp Immunol; 2016 Feb; 183(2):221-9. PubMed ID: 26437962
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in
    Dornan GL; Siempelkamp BD; Jenkins ML; Vadas O; Lucas CL; Burke JE
    Proc Natl Acad Sci U S A; 2017 Feb; 114(8):1982-1987. PubMed ID: 28167755
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the
    Wang W; Min Q; Lai N; Csomos K; Wang Y; Liu L; Meng X; Sun J; Hou J; Ying W; Zhou Q; Sun B; Hui X; Ujhazi B; Gordon S; Buchbinder D; Schuetz C; Butte M; Walter JE; Wang X; Wang JY
    Front Immunol; 2022; 13():890073. PubMed ID: 35799777
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gain-of-function mutation in PIK3R1 in a patient with a narrow clinical phenotype of respiratory infections.
    Martínez-Saavedra MT; García-Gomez S; Domínguez Acosta A; Mendoza Quintana JJ; Páez JP; García-Reino EJ; Camps G; Martinez-Barricarte R; Itan Y; Boisson B; Sánchez-Ramón S; Regueiro JR; Casanova JL; Rodríguez-Gallego C; Pérez de Diego R
    Clin Immunol; 2016 Dec; 173():117-120. PubMed ID: 27693481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.
    Nguyen T; Lau A; Bier J; Cooke KC; Lenthall H; Ruiz-Diaz S; Avery DT; Brigden H; Zahra D; Sewell WA; Droney L; Okada S; Asano T; Abolhassani H; Chavoshzadeh Z; Abraham RS; Rajapakse N; Klee EW; Church JA; Williams A; Wong M; Burkhart C; Uzel G; Croucher DR; James DE; Ma CS; Brink R; Tangye SG; Deenick EK
    J Exp Med; 2023 Jun; 220(6):. PubMed ID: 36943234
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity.
    Edwards ESJ; Bier J; Cole TS; Wong M; Hsu P; Berglund LJ; Boztug K; Lau A; Gostick E; Price DA; O'Sullivan M; Meyts I; Choo S; Gray P; Holland SM; Deenick EK; Uzel G; Tangye SG
    J Allergy Clin Immunol; 2019 Jan; 143(1):276-291.e6. PubMed ID: 29800648
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling.
    Omori SA; Cato MH; Anzelon-Mills A; Puri KD; Shapiro-Shelef M; Calame K; Rickert RC
    Immunity; 2006 Oct; 25(4):545-57. PubMed ID: 17000121
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The case of an APDS patient: Defects in maturation and function and decreased in vitro anti-mycobacterial activity in the myeloid compartment.
    Chiriaco M; Brigida I; Ariganello P; Di Cesare S; Di Matteo G; Taus F; Cittaro D; Lazarevic D; Scarselli A; Santilli V; Attardi E; Stupka E; Giannelli S; Fraziano M; Finocchi A; Rossi P; Aiuti A; Palma P; Cancrini C
    Clin Immunol; 2017 May; 178():20-28. PubMed ID: 26732860
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory.
    Gitlin AD; von Boehmer L; Gazumyan A; Shulman Z; Oliveira TY; Nussenzweig MC
    Immunity; 2016 Apr; 44(4):769-81. PubMed ID: 26944202
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.
    Chen Z; Getahun A; Chen X; Dollin Y; Cambier JC; Wang JH
    J Immunol; 2015 Dec; 195(11):5461-5471. PubMed ID: 26500350
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Abnormal B-cell maturation in the bone marrow of patients with germline mutations in PIK3CD.
    Dulau Florea AE; Braylan RC; Schafernak KT; Williams KW; Daub J; Goyal RK; Puck JM; Rao VK; Pittaluga S; Holland SM; Uzel G; Calvo KR
    J Allergy Clin Immunol; 2017 Mar; 139(3):1032-1035.e6. PubMed ID: 27697496
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High affinity IgM(+) memory B cells are generated through a germinal center-dependent pathway.
    Hara Y; Tashiro Y; Murakami A; Nishimura M; Shimizu T; Kubo M; Burrows PD; Azuma T
    Mol Immunol; 2015 Dec; 68(2 Pt C):617-27. PubMed ID: 26514429
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of a novel de novo gain-of-function mutation of PIK3CD in a patient with activated phosphoinositide 3-kinase δ syndrome.
    Luo Y; Xia Y; Wang W; Li Z; Jin Y; Gong Y; He T; Li Q; Li C; Yang J
    Clin Immunol; 2018 Dec; 197():60-67. PubMed ID: 30138677
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.