BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

672 related articles for article (PubMed ID: 28104905)

  • 1. Applications of chemogenomic library screening in drug discovery.
    Jones LH; Bunnage ME
    Nat Rev Drug Discov; 2017 Apr; 16(4):285-296. PubMed ID: 28104905
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemical screening in zebrafish for novel biological and therapeutic discovery.
    Tan JL; Zon LI
    Methods Cell Biol; 2011; 105():493-516. PubMed ID: 21951544
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel approaches to map small molecule-target interactions.
    Kapoor S; Waldmann H; Ziegler S
    Bioorg Med Chem; 2016 Aug; 24(15):3232-45. PubMed ID: 27240466
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Systematic Identification of Pharmacological Targets from Small-Molecule Phenotypic Screens.
    Liu X; Baarsma HA; Thiam CH; Montrone C; Brauner B; Fobo G; Heier JS; Duscha S; Königshoff M; Angeli V; Ruepp A; Campillos M
    Cell Chem Biol; 2016 Oct; 23(10):1302-1313. PubMed ID: 27667560
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Target Identification Using Chemical Probes.
    Moustakim M; Felce SL; Zaarour N; Farnie G; McCann FE; Brennan PE
    Methods Enzymol; 2018; 610():27-58. PubMed ID: 30390803
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and validation of bioactive small molecule target through phenotypic screening.
    Cho YS; Kwon HJ
    Bioorg Med Chem; 2012 Mar; 20(6):1922-8. PubMed ID: 22153994
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Open-source chemogenomic data-driven algorithms for predicting drug-target interactions.
    Hao M; Bryant SH; Wang Y
    Brief Bioinform; 2019 Jul; 20(4):1465-1474. PubMed ID: 29420684
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Opportunities and challenges in phenotypic drug discovery: an industry perspective.
    Moffat JG; Vincent F; Lee JA; Eder J; Prunotto M
    Nat Rev Drug Discov; 2017 Aug; 16(8):531-543. PubMed ID: 28685762
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of drug candidates and repurposing opportunities through compound-target interaction networks.
    Cichonska A; Rousu J; Aittokallio T
    Expert Opin Drug Discov; 2015 Dec; 10(12):1333-45. PubMed ID: 26429153
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Compound Libraries: Recent Advances and Their Applications in Drug Discovery.
    Gong Z; Hu G; Li Q; Liu Z; Wang F; Zhang X; Xiong J; Li P; Xu Y; Ma R; Chen S; Li J
    Curr Drug Discov Technol; 2017; 14(4):216-228. PubMed ID: 28443514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small molecules and their role in effective preclinical target validation.
    Clegg MA; Tomkinson NC; Prinjha RK; Humphreys PG
    Future Med Chem; 2017 Sep; 9(14):1579-1582. PubMed ID: 28828889
    [No Abstract]   [Full Text] [Related]  

  • 12. Advancing the kinase field: new targets and second generation inhibitors.
    Laufer S; Bajorath J
    J Med Chem; 2015 Jan; 58(1):1. PubMed ID: 25490234
    [No Abstract]   [Full Text] [Related]  

  • 13. The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.
    Janes J; Young ME; Chen E; Rogers NH; Burgstaller-Muehlbacher S; Hughes LD; Love MS; Hull MV; Kuhen KL; Woods AK; Joseph SB; Petrassi HM; McNamara CW; Tremblay MS; Su AI; Schultz PG; Chatterjee AK
    Proc Natl Acad Sci U S A; 2018 Oct; 115(42):10750-10755. PubMed ID: 30282735
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Macromolecular target prediction by self-organizing feature maps.
    Schneider G; Schneider P
    Expert Opin Drug Discov; 2017 Mar; 12(3):271-277. PubMed ID: 27997811
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Computational Toxicology Methods in Chemical Library Design and High-Throughput Screening Hit Validation.
    Hevener KE
    Methods Mol Biol; 2018; 1800():275-285. PubMed ID: 29934898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator].
    Prudent R; Soleilhac E; Barette C; Fauvarque MO; Lafanechère L
    Med Sci (Paris); 2013 Oct; 29(10):897-905. PubMed ID: 24148129
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biodiversity of small molecules--a new perspective in screening set selection.
    Petrone PM; Wassermann AM; Lounkine E; Kutchukian P; Simms B; Jenkins J; Selzer P; Glick M
    Drug Discov Today; 2013 Jul; 18(13-14):674-80. PubMed ID: 23454345
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increasing the delivery of next generation therapeutics from high throughput screening libraries.
    Wigglesworth MJ; Murray DC; Blackett CJ; Kossenjans M; Nissink JW
    Curr Opin Chem Biol; 2015 Jun; 26():104-10. PubMed ID: 25909818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry.
    Deprez B; Bosc D; Charton J; Couturier C; Deprez-Poulain R; Flipo M; Leroux F; Villemagne B; Willand N
    Molecules; 2021 Oct; 26(19):. PubMed ID: 34641626
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fragments and hot spots in drug discovery.
    Vajda S; Whitty A; Kozakov D
    Oncotarget; 2015 Aug; 6(22):18740-1. PubMed ID: 26300051
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 34.