BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 28106753)

  • 1. Naphthalimides Selectively Inhibit the Activity of Bacterial, Replicative DNA Ligases and Display Bactericidal Effects against Tubercle Bacilli.
    Korycka-Machala M; Nowosielski M; Kuron A; Rykowski S; Olejniczak A; Hoffmann M; Dziadek J
    Molecules; 2017 Jan; 22(1):. PubMed ID: 28106753
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mycobacterium tuberculosis NAD+-dependent DNA ligase is selectively inhibited by glycosylamines compared with human DNA ligase I.
    Srivastava SK; Dube D; Tewari N; Dwivedi N; Tripathi RP; Ramachandran R
    Nucleic Acids Res; 2005; 33(22):7090-101. PubMed ID: 16361267
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Toward the virtual screening of potential drugs in the homology modeled NAD+ dependent DNA ligase from Mycobacterium tuberculosis.
    Singh V; Somvanshi P
    Protein Pept Lett; 2010 Feb; 17(2):269-76. PubMed ID: 20214650
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tricyclic dihydrobenzoxazepine and tetracyclic indole derivatives can specifically target bacterial DNA ligases and can distinguish them from human DNA ligase I.
    Yadav N; Khanam T; Shukla A; Rai N; Hajela K; Ramachandran R
    Org Biomol Chem; 2015 May; 13(19):5475-87. PubMed ID: 25875403
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Base-modified NAD and AMP derivatives and their activity against bacterial DNA ligases.
    Pergolizzi G; Cominetti MM; Butt JN; Field RA; Bowater RP; Wagner GK
    Org Biomol Chem; 2015 Jun; 13(22):6380-98. PubMed ID: 25974621
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a novel inhibitor of isocitrate lyase as a potent antitubercular agent against both active and non-replicating Mycobacterium tuberculosis.
    Liu Y; Zhou S; Deng Q; Li X; Meng J; Guan Y; Li C; Xiao C
    Tuberculosis (Edinb); 2016 Mar; 97():38-46. PubMed ID: 26980494
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD
    Shukla A; Afsar M; Kumar N; Kumar S; Ramachandran R
    J Struct Biol; 2021 Mar; 213(1):107655. PubMed ID: 33197566
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NAD+-dependent DNA Ligase (Rv3014c) from Mycobacterium tuberculosis. Crystal structure of the adenylation domain and identification of novel inhibitors.
    Srivastava SK; Tripathi RP; Ramachandran R
    J Biol Chem; 2005 Aug; 280(34):30273-81. PubMed ID: 15901723
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High-throughput screen identifies small molecule inhibitors targeting acetyltransferase activity of Mycobacterium tuberculosis GlmU.
    Rani C; Mehra R; Sharma R; Chib R; Wazir P; Nargotra A; Khan IA
    Tuberculosis (Edinb); 2015 Dec; 95(6):664-677. PubMed ID: 26318557
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NAD+-dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: novel structure-function relationship and identification of a specific inhibitor.
    Srivastava SK; Dube D; Kukshal V; Jha AK; Hajela K; Ramachandran R
    Proteins; 2007 Oct; 69(1):97-111. PubMed ID: 17557328
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Editorial: Current status and perspective on drug targets in tubercle bacilli and drug design of antituberculous agents based on structure-activity relationship.
    Tomioka H
    Curr Pharm Des; 2014; 20(27):4305-6. PubMed ID: 24245755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification and characterization of an inhibitor specific to bacterial NAD+-dependent DNA ligases.
    Meier TI; Yan D; Peery RB; McAllister KA; Zook C; Peng SB; Zhao G
    FEBS J; 2008 Nov; 275(21):5258-71. PubMed ID: 18795946
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Study of mechanism of interaction of truncated isoniazid-nicotinamide adenine dinucleotide adduct against multiple enzymes of Mycobacterium tuberculosis by a computational approach.
    Jena L; Deshmukh S; Waghmare P; Kumar S; Harinath BC
    Int J Mycobacteriol; 2015 Dec; 4(4):276-83. PubMed ID: 26964808
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors.
    Esposito M; Szadocka S; Degiacomi G; Orena BS; Mori G; Piano V; Boldrin F; Zemanová J; Huszár S; Barros D; Ekins S; Lelièvre J; Manganelli R; Mattevi A; Pasca MR; Riccardi G; Ballell L; Mikušová K; Chiarelli LR
    ACS Infect Dis; 2017 Jun; 3(6):428-437. PubMed ID: 28475832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and Optimization of NAD+-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds.
    Bi F; Ma R; Ma S
    Curr Pharm Des; 2017; 23(14):2117-2130. PubMed ID: 27784238
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel bacterial NAD+-dependent DNA ligase inhibitors with broad-spectrum activity and antibacterial efficacy in vivo.
    Mills SD; Eakin AE; Buurman ET; Newman JV; Gao N; Huynh H; Johnson KD; Lahiri S; Shapiro AB; Walkup GK; Yang W; Stokes SS
    Antimicrob Agents Chemother; 2011 Mar; 55(3):1088-96. PubMed ID: 21189350
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis.
    Guzman JD; Gupta A; Evangelopoulos D; Basavannacharya C; Pabon LC; Plazas EA; Muñoz DR; Delgado WA; Cuca LE; Ribon W; Gibbons S; Bhakta S
    J Antimicrob Chemother; 2010 Oct; 65(10):2101-7. PubMed ID: 20719764
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High throughput screen identifies small molecule inhibitors specific for Mycobacterium tuberculosis phosphoserine phosphatase.
    Arora G; Tiwari P; Mandal RS; Gupta A; Sharma D; Saha S; Singh R
    J Biol Chem; 2014 Sep; 289(36):25149-65. PubMed ID: 25037224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mycobacterial DNA Replication as a Target for Antituberculosis Drug Discovery.
    Płocinska R; Korycka-Machala M; Plocinski P; Dziadek J
    Curr Top Med Chem; 2017 Jun; 17(19):2129-2142. PubMed ID: 28137234
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Screening of antitubercular compound library identifies novel ATP synthase inhibitors of Mycobacterium tuberculosis.
    Kumar S; Mehra R; Sharma S; Bokolia NP; Raina D; Nargotra A; Singh PP; Khan IA
    Tuberculosis (Edinb); 2018 Jan; 108():56-63. PubMed ID: 29523328
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.