BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 28107181)

  • 1. Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer.
    Alexander A; Karakas C; Chen X; Carey JP; Yi M; Bondy M; Thompson P; Cheung KL; Ellis IO; Gong Y; Krishnamurthy S; Alvarez RH; Ueno NT; Hunt KK; Keyomarsi K
    Oncotarget; 2017 Feb; 8(9):14897-14911. PubMed ID: 28107181
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective Targeting of Cyclin E1-Amplified High-Grade Serous Ovarian Cancer by Cyclin-Dependent Kinase 2 and AKT Inhibition.
    Au-Yeung G; Lang F; Azar WJ; Mitchell C; Jarman KE; Lackovic K; Aziz D; Cullinane C; Pearson RB; Mileshkin L; Rischin D; Karst AM; Drapkin R; Etemadmoghadam D; Bowtell DD
    Clin Cancer Res; 2017 Apr; 23(7):1862-1874. PubMed ID: 27663592
    [No Abstract]   [Full Text] [Related]  

  • 3. Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer.
    Doostan I; Karakas C; Kohansal M; Low KH; Ellis MJ; Olson JA; Suman VJ; Hunt KK; Moulder SL; Keyomarsi K
    Clin Cancer Res; 2017 Dec; 23(23):7288-7300. PubMed ID: 28947566
    [No Abstract]   [Full Text] [Related]  

  • 4. Hyperactivated mTOR and JAK2/STAT3 Pathways: Molecular Drivers and Potential Therapeutic Targets of Inflammatory and Invasive Ductal Breast Cancers After Neoadjuvant Chemotherapy.
    Jhaveri K; Teplinsky E; Silvera D; Valeta-Magara A; Arju R; Giashuddin S; Sarfraz Y; Alexander M; Darvishian F; Levine PH; Hashmi S; Zolfaghari L; Hoffman HJ; Singh B; Goldberg JD; Hochman T; Formenti S; Esteva FJ; Moran MS; Schneider RJ
    Clin Breast Cancer; 2016 Apr; 16(2):113-22.e1. PubMed ID: 26774497
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Cdk2 kinase activity selectively targets the CD44⁺/CD24⁻/Low stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells.
    Opyrchal M; Salisbury JL; Iankov I; Goetz MP; McCubrey J; Gambino MW; Malatino L; Puccia G; Ingle JN; Galanis E; D'Assoro AB
    Int J Oncol; 2014 Sep; 45(3):1193-9. PubMed ID: 24970653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition.
    Chen X; Low KH; Alexander A; Jiang Y; Karakas C; Hess KR; Carey JPW; Bui TN; Vijayaraghavan S; Evans KW; Yi M; Ellis DC; Cheung KL; Ellis IO; Fu S; Meric-Bernstam F; Hunt KK; Keyomarsi K
    Clin Cancer Res; 2018 Dec; 24(24):6594-6610. PubMed ID: 30181387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MARCKS protein overexpression in inflammatory breast cancer.
    Manai M; Thomassin-Piana J; Gamoudi A; Finetti P; Lopez M; Eghozzi R; Ayadi S; Lamine OB; Manai M; Rahal K; Charafe-Jauffret E; Jacquemier J; Viens P; Birnbaum D; Boussen H; Chaffanet M; Bertucci F
    Oncotarget; 2017 Jan; 8(4):6246-6257. PubMed ID: 28009981
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics.
    Choudhary GS; Tat TT; Misra S; Hill BT; Smith MR; Almasan A; Mazumder S
    Oncotarget; 2015 Jul; 6(19):16912-25. PubMed ID: 26219338
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies.
    Caruso JA; Duong MT; Carey JPW; Hunt KK; Keyomarsi K
    Cancer Res; 2018 Oct; 78(19):5481-5491. PubMed ID: 30194068
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression.
    Yang L; Fang D; Chen H; Lu Y; Dong Z; Ding HF; Jing Q; Su SB; Huang S
    Oncotarget; 2015 Aug; 6(25):20801-12. PubMed ID: 26204491
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impact of cyclin E overexpression on Smad3 activity in breast cancer cell lines.
    Cooley A; Zelivianski S; Jeruss JS
    Cell Cycle; 2010 Dec; 9(24):4900-7. PubMed ID: 21150326
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phase 1 safety, pharmacokinetic and pharmacodynamic study of the cyclin-dependent kinase inhibitor dinaciclib administered every three weeks in patients with advanced malignancies.
    Mita MM; Mita AC; Moseley JL; Poon J; Small KA; Jou YM; Kirschmeier P; Zhang D; Zhu Y; Statkevich P; Sankhala KK; Sarantopoulos J; Cleary JM; Chirieac LR; Rodig SJ; Bannerji R; Shapiro GI
    Br J Cancer; 2017 Oct; 117(9):1258-1268. PubMed ID: 28859059
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2.
    Danilov AV; Hu S; Orr B; Godek K; Mustachio LM; Sekula D; Liu X; Kawakami M; Johnson FM; Compton DA; Freemantle SJ; Dmitrovsky E
    Mol Cancer Ther; 2016 Nov; 15(11):2758-2766. PubMed ID: 27550941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancer.
    Rajput S; Khera N; Guo Z; Hoog J; Li S; Ma CX
    Oncotarget; 2016 Aug; 7(35):56864-56875. PubMed ID: 27486754
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ZYG11A serves as an oncogene in non-small cell lung cancer and influences CCNE1 expression.
    Wang X; Sun Q; Chen C; Yin R; Huang X; Wang X; Shi R; Xu L; Ren B
    Oncotarget; 2016 Feb; 7(7):8029-42. PubMed ID: 26771237
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer.
    Liang X; Vacher S; Boulai A; Bernard V; Baulande S; Bohec M; Bièche I; Lerebours F; Callens C
    Breast Cancer Res; 2018 Aug; 20(1):88. PubMed ID: 30086764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overall survival differences between patients with inflammatory and noninflammatory breast cancer presenting with distant metastasis at diagnosis.
    Fouad TM; Kogawa T; Liu DD; Shen Y; Masuda H; El-Zein R; Woodward WA; Chavez-MacGregor M; Alvarez RH; Arun B; Lucci A; Krishnamurthy S; Babiera G; Buchholz TA; Valero V; Ueno NT
    Breast Cancer Res Treat; 2015 Jul; 152(2):407-16. PubMed ID: 26017070
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CK1δ activity is modulated by CDK2/E- and CDK5/p35-mediated phosphorylation.
    Ianes C; Xu P; Werz N; Meng Z; Henne-Bruns D; Bischof J; Knippschild U
    Amino Acids; 2016 Feb; 48(2):579-92. PubMed ID: 26464264
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dinaciclib for the treatment of breast cancer.
    Criscitiello C; Viale G; Esposito A; Curigliano G
    Expert Opin Investig Drugs; 2014 Sep; 23(9):1305-12. PubMed ID: 25107301
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytoplasmic Cyclin E and Phospho-Cyclin-Dependent Kinase 2 Are Biomarkers of Aggressive Breast Cancer.
    Karakas C; Biernacka A; Bui T; Sahin AA; Yi M; Akli S; Schafer J; Alexander A; Adjapong O; Hunt KK; Keyomarsi K
    Am J Pathol; 2016 Jul; 186(7):1900-1912. PubMed ID: 27182644
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.