593 related articles for article (PubMed ID: 28111073)
1. Ligand and Target Discovery by Fragment-Based Screening in Human Cells.
Parker CG; Galmozzi A; Wang Y; Correia BE; Sasaki K; Joslyn CM; Kim AS; Cavallaro CL; Lawrence RM; Johnson SR; Narvaiza I; Saez E; Cravatt BF
Cell; 2017 Jan; 168(3):527-541.e29. PubMed ID: 28111073
[TBL] [Abstract][Full Text] [Related]
2. Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90.
Riccardi Sirtori F; Caronni D; Colombo M; Dalvit C; Paolucci M; Regazzoni L; Visco C; Fogliatto G
Eur J Pharm Sci; 2015 Aug; 76():83-94. PubMed ID: 25952103
[TBL] [Abstract][Full Text] [Related]
3. Mass spectrometry for fragment screening.
Chan DS; Whitehouse AJ; Coyne AG; Abell C
Essays Biochem; 2017 Nov; 61(5):465-473. PubMed ID: 28986384
[TBL] [Abstract][Full Text] [Related]
4. Discovery of Modulators of Adipocyte Physiology Using Fully Functionalized Fragments.
Galmozzi A; Parker CG; Kok BP; Cravatt BF; Saez E
Methods Mol Biol; 2018; 1787():115-127. PubMed ID: 29736714
[TBL] [Abstract][Full Text] [Related]
5. Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells.
Offensperger F; Tin G; Duran-Frigola M; Hahn E; Dobner S; Ende CWA; Strohbach JW; Rukavina A; Brennsteiner V; Ogilvie K; Marella N; Kladnik K; Ciuffa R; Majmudar JD; Field SD; Bensimon A; Ferrari L; Ferrada E; Ng A; Zhang Z; Degliesposti G; Boeszoermenyi A; Martens S; Stanton R; Müller AC; Hannich JT; Hepworth D; Superti-Furga G; Kubicek S; Schenone M; Winter GE
Science; 2024 Apr; 384(6694):eadk5864. PubMed ID: 38662832
[TBL] [Abstract][Full Text] [Related]
6. NMR spectroscopy: the swiss army knife of drug discovery.
Horst R; Farley KA; Kormos BL; Withka JM
J Biomol NMR; 2020 Nov; 74(10-11):509-519. PubMed ID: 32617727
[TBL] [Abstract][Full Text] [Related]
7. Biophysical screening for the discovery of small-molecule ligands.
Ciulli A
Methods Mol Biol; 2013; 1008():357-88. PubMed ID: 23729259
[TBL] [Abstract][Full Text] [Related]
8. Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
Recht MI; Sridhar V; Badger J; Bounaud PY; Logan C; Chie-Leon B; Nienaber V; Torres FE
J Biomol Screen; 2014 Apr; 19(4):497-507. PubMed ID: 24375910
[TBL] [Abstract][Full Text] [Related]
9. Efficiency of hit generation and structural characterization in fragment-based ligand discovery.
Larsson A; Jansson A; Åberg A; Nordlund P
Curr Opin Chem Biol; 2011 Aug; 15(4):482-8. PubMed ID: 21724447
[TBL] [Abstract][Full Text] [Related]
10. Fragment-based screening with natural products for novel anti-parasitic disease drug discovery.
Liu M; Quinn RJ
Expert Opin Drug Discov; 2019 Dec; 14(12):1283-1295. PubMed ID: 31512943
[No Abstract] [Full Text] [Related]
11. Recent progress in fragment-based lead discovery.
Schulz MN; Hubbard RE
Curr Opin Pharmacol; 2009 Oct; 9(5):615-21. PubMed ID: 19477685
[TBL] [Abstract][Full Text] [Related]
12. Counting on Fragment Based Drug Design Approach for Drug Discovery.
Kashyap A; Singh PK; Silakari O
Curr Top Med Chem; 2018; 18(27):2284-2293. PubMed ID: 30499406
[TBL] [Abstract][Full Text] [Related]
13. Fragment Screening by NMR.
Davis BJ
Methods Mol Biol; 2021; 2263():247-270. PubMed ID: 33877602
[TBL] [Abstract][Full Text] [Related]
14. Combining biophysical screening and X-ray crystallography for fragment-based drug discovery.
Hennig M; Ruf A; Huber W
Top Curr Chem; 2012; 317():115-43. PubMed ID: 21837555
[TBL] [Abstract][Full Text] [Related]
15. An Array-Based Ligand Discovery Platform for Proteins With Short Half-Lives.
Leifer BS; Doyle SK; Richters A; Evans HL; Koehler AN
Methods Enzymol; 2018; 610():191-218. PubMed ID: 30390799
[TBL] [Abstract][Full Text] [Related]
16. Fragment-based approaches in drug discovery and chemical biology.
Scott DE; Coyne AG; Hudson SA; Abell C
Biochemistry; 2012 Jun; 51(25):4990-5003. PubMed ID: 22697260
[TBL] [Abstract][Full Text] [Related]
17. Fragment-based drug discovery and its application to challenging drug targets.
Price AJ; Howard S; Cons BD
Essays Biochem; 2017 Nov; 61(5):475-484. PubMed ID: 29118094
[TBL] [Abstract][Full Text] [Related]
18. [Fragment-based lead discovery from smaller fragments to functional ligand].
Hatayama A; Habashita H
Tanpakushitsu Kakusan Koso; 2009 Sep; 54(12 Suppl):1611-6. PubMed ID: 21089596
[No Abstract] [Full Text] [Related]
19. Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening.
Wu CY; Wang DH; Wang X; Dixon SM; Meng L; Ahadi S; Enter DH; Chen CY; Kato J; Leon LJ; Ramirez LM; Maeda Y; Reis CF; Ribeiro B; Weems B; Kung HJ; Lam KS
ACS Comb Sci; 2016 Jun; 18(6):320-9. PubMed ID: 27053324
[TBL] [Abstract][Full Text] [Related]
20. NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds.
Yu JL; Chen TT; Zhou C; Lian FL; Tang XL; Wen Y; Shen JK; Xu YC; Xiong B; Zhang NX
Acta Pharmacol Sin; 2016 Jul; 37(7):984-93. PubMed ID: 27238211
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]