226 related articles for article (PubMed ID: 28123935)
1. Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion.
Remsberg JR; Ediger BN; Ho WY; Damle M; Li Z; Teng C; Lanzillotta C; Stoffers DA; Lazar MA
Mol Metab; 2017 Jan; 6(1):30-37. PubMed ID: 28123935
[TBL] [Abstract][Full Text] [Related]
2. Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes.
Chen WB; Gao L; Wang J; Wang YG; Dong Z; Zhao J; Mi QS; Zhou L
Oncotarget; 2016 Sep; 7(36):57485-57497. PubMed ID: 27542279
[TBL] [Abstract][Full Text] [Related]
3. Histone deacetylase inhibition by MS-275 potentiates glucose-stimulated insulin secretion without affecting glucose oxidation.
Zhang Y; Li M; Wang Y; Liu X; Zhou L; Zhang C; Shao L
Life Sci; 2020 Sep; 257():118073. PubMed ID: 32663574
[TBL] [Abstract][Full Text] [Related]
4. Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Zhang Y; Wang S; Zhang L; Zhou F; Zhu K; Zhu Q; Liu Q; Liu Y; Jiang L; Ning G; Bi Y; Zhou L; Wang X
Theranostics; 2020; 10(16):7351-7368. PubMed ID: 32641996
[No Abstract] [Full Text] [Related]
5. SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
Qin K; Zhang N; Zhang Z; Nipper M; Zhu Z; Leighton J; Xu K; Musi N; Wang P
Diabetologia; 2018 Apr; 61(4):906-918. PubMed ID: 29322219
[TBL] [Abstract][Full Text] [Related]
6. Histone deacetylase 3-selective inhibitor RGFP966 ameliorates impaired glucose tolerance through β-cell protection.
Lei L; Bai G; Wang X; Liu S; Xia J; Wu S; Huan Y; Shen Z
Toxicol Appl Pharmacol; 2020 Nov; 406():115189. PubMed ID: 32800772
[TBL] [Abstract][Full Text] [Related]
7. Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children.
Lundh M; Christensen DP; Damgaard Nielsen M; Richardson SJ; Dahllöf MS; Skovgaard T; Berthelsen J; Dinarello CA; Stevenazzi A; Mascagni P; Grunnet LG; Morgan NG; Mandrup-Poulsen T
Diabetologia; 2012 Sep; 55(9):2421-31. PubMed ID: 22772764
[TBL] [Abstract][Full Text] [Related]
8. Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats.
Lundh M; Galbo T; Poulsen SS; Mandrup-Poulsen T
Diabetes Obes Metab; 2015 Jul; 17(7):703-7. PubMed ID: 25846481
[TBL] [Abstract][Full Text] [Related]
9. Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes.
Dirice E; Ng RWS; Martinez R; Hu J; Wagner FF; Holson EB; Wagner BK; Kulkarni RN
J Biol Chem; 2017 Oct; 292(43):17598-17608. PubMed ID: 28860191
[TBL] [Abstract][Full Text] [Related]
10. MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation.
Daneshpajooh M; Eliasson L; Bacos K; Ling C
Acta Diabetol; 2018 Dec; 55(12):1231-1235. PubMed ID: 30088095
[TBL] [Abstract][Full Text] [Related]
11. Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance.
Skovsø S; Panzhinskiy E; Kolic J; Cen HH; Dionne DA; Dai XQ; Sharma RB; Elghazi L; Ellis CE; Faulkner K; Marcil SAM; Overby P; Noursadeghi N; Hutchinson D; Hu X; Li H; Modi H; Wildi JS; Botezelli JD; Noh HL; Suk S; Gablaski B; Bautista A; Kim R; Cras-Méneur C; Flibotte S; Sinha S; Luciani DS; Nislow C; Rideout EJ; Cytrynbaum EN; Kim JK; Bernal-Mizrachi E; Alonso LC; MacDonald PE; Johnson JD
Nat Commun; 2022 Feb; 13(1):735. PubMed ID: 35136059
[TBL] [Abstract][Full Text] [Related]
12. HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells.
Daneshpajooh M; Bacos K; Bysani M; Bagge A; Ottosson Laakso E; Vikman P; Eliasson L; Mulder H; Ling C
Diabetologia; 2017 Jan; 60(1):116-125. PubMed ID: 27796421
[TBL] [Abstract][Full Text] [Related]
13. Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.
Cantley J; Choudhury AI; Asare-Anane H; Selman C; Lingard S; Heffron H; Herrera P; Persaud SJ; Withers DJ
Diabetologia; 2007 Jun; 50(6):1248-56. PubMed ID: 17393136
[TBL] [Abstract][Full Text] [Related]
14. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
Bensellam M; Shi YC; Chan JY; Laybutt DR; Chae H; Abou-Samra M; Pappas EG; Thomas HE; Gilon P; Jonas JC
Diabetologia; 2019 Dec; 62(12):2273-2286. PubMed ID: 31624901
[TBL] [Abstract][Full Text] [Related]
15. Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice.
Choi D; Cai EP; Schroer SA; Wang L; Woo M
Lab Invest; 2011 Apr; 91(4):527-38. PubMed ID: 21242957
[TBL] [Abstract][Full Text] [Related]
16. LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.
Sun G; Tarasov AI; McGinty JA; French PM; McDonald A; Leclerc I; Rutter GA
Am J Physiol Endocrinol Metab; 2010 Jun; 298(6):E1261-73. PubMed ID: 20354156
[TBL] [Abstract][Full Text] [Related]
17. Deletion of ARNT/HIF1β in pancreatic beta cells does not impair glucose homeostasis in mice, but is associated with defective glucose sensing ex vivo.
Pillai R; Paglialunga S; Hoang M; Cousteils K; Prentice KJ; Bombardier E; Huang M; Gonzalez FJ; Tupling AR; Wheeler MB; Joseph JW
Diabetologia; 2015 Dec; 58(12):2832-42. PubMed ID: 26409461
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis.
Chou DH; Holson EB; Wagner FF; Tang AJ; Maglathlin RL; Lewis TA; Schreiber SL; Wagner BK
Chem Biol; 2012 Jun; 19(6):669-73. PubMed ID: 22726680
[TBL] [Abstract][Full Text] [Related]
19. Long-term c-Kit overexpression in beta cells compromises their function in ageing mice.
Oakie A; Feng ZC; Li J; Silverstein J; Yee SP; Wang R
Diabetologia; 2019 Aug; 62(8):1430-1444. PubMed ID: 31154478
[TBL] [Abstract][Full Text] [Related]
20. TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.
Takamoto I; Kubota N; Nakaya K; Kumagai K; Hashimoto S; Kubota T; Inoue M; Kajiwara E; Katsuyama H; Obata A; Sakurai Y; Iwamoto M; Kitamura T; Ueki K; Kadowaki T
Diabetologia; 2014 Mar; 57(3):542-53. PubMed ID: 24317852
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
