These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

501 related articles for article (PubMed ID: 28124441)

  • 1. Confirmation of mutation landscape of NF1-associated malignant peripheral nerve sheath tumors.
    Sohier P; Luscan A; Lloyd A; Ashelford K; Laurendeau I; Briand-Suleau A; Vidaud D; Ortonne N; Pasmant E; Upadhyaya M
    Genes Chromosomes Cancer; 2017 May; 56(5):421-426. PubMed ID: 28124441
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low mutation burden and frequent loss of CDKN2A/B and SMARCA2, but not PRC2, define premalignant neurofibromatosis type 1-associated atypical neurofibromas.
    Pemov A; Hansen NF; Sindiri S; Patidar R; Higham CS; Dombi E; Miettinen MM; Fetsch P; Brems H; Chandrasekharappa SC; Jones K; Zhu B; Wei JS; ; ; Mullikin JC; Wallace MR; Khan J; Legius E; Widemann BC; Stewart DR
    Neuro Oncol; 2019 Aug; 21(8):981-992. PubMed ID: 30722027
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the somatic mutational spectrum of the neurofibromatosis type 1 (NF1) gene in neurofibromatosis patients with benign and malignant tumors.
    Upadhyaya M; Han S; Consoli C; Majounie E; Horan M; Thomas NS; Potts C; Griffiths S; Ruggieri M; von Deimling A; Cooper DN
    Hum Mutat; 2004 Feb; 23(2):134-146. PubMed ID: 14722917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular evolution of a neurofibroma to malignant peripheral nerve sheath tumor (MPNST) in an NF1 patient: correlation between histopathological, clinical and molecular findings.
    Spurlock G; Knight SJ; Thomas N; Kiehl TR; Guha A; Upadhyaya M
    J Cancer Res Clin Oncol; 2010 Dec; 136(12):1869-80. PubMed ID: 20229272
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Germline and somatic NF1 gene mutation spectrum in NF1-associated malignant peripheral nerve sheath tumors (MPNSTs).
    Upadhyaya M; Kluwe L; Spurlock G; Monem B; Majounie E; Mantripragada K; Ruggieri M; Chuzhanova N; Evans DG; Ferner R; Thomas N; Guha A; Mautner V
    Hum Mutat; 2008 Jan; 29(1):74-82. PubMed ID: 17960768
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.
    Lee W; Teckie S; Wiesner T; Ran L; Prieto Granada CN; Lin M; Zhu S; Cao Z; Liang Y; Sboner A; Tap WD; Fletcher JA; Huberman KH; Qin LX; Viale A; Singer S; Zheng D; Berger MF; Chen Y; Antonescu CR; Chi P
    Nat Genet; 2014 Nov; 46(11):1227-32. PubMed ID: 25240281
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.
    Park HJ; Lee SJ; Sohn YB; Jin HS; Han JH; Kim YB; Yim H; Jeong SY
    Int J Oncol; 2013 Feb; 42(2):657-66. PubMed ID: 23292448
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells.
    Varin J; Poulain L; Hivelin M; Nusbaum P; Hubas A; Laurendeau I; Lantieri L; Wolkenstein P; Vidaud M; Pasmant E; Chapuis N; Parfait B
    Oncotarget; 2016 Jun; 7(24):35753-35767. PubMed ID: 26840085
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma.
    Hirbe AC; Dahiya S; Miller CA; Li T; Fulton RS; Zhang X; McDonald S; DeSchryver K; Duncavage EJ; Walrath J; Reilly KM; Abel HJ; Pekmezci M; Perry A; Ley TJ; Gutmann DH
    Clin Cancer Res; 2015 Sep; 21(18):4201-11. PubMed ID: 25925892
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association between benign and malignant peripheral nerve sheath tumors in NF1.
    Tucker T; Wolkenstein P; Revuz J; Zeller J; Friedman JM
    Neurology; 2005 Jul; 65(2):205-11. PubMed ID: 16043787
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1.
    McPherson JR; Ong CK; Ng CC; Rajasegaran V; Heng HL; Yu WS; Tan BK; Madhukumar P; Teo MC; Ngeow J; Thike AA; Rozen SG; Tan PH; Lee AS; Teh BT; Yap YS
    Cancer Med; 2015 Dec; 4(12):1871-8. PubMed ID: 26432421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis.
    Kazmi SJ; Byer SJ; Eckert JM; Turk AN; Huijbregts RP; Brossier NM; Grizzle WE; Mikhail FM; Roth KA; Carroll SL
    Am J Pathol; 2013 Mar; 182(3):646-67. PubMed ID: 23321323
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors.
    Beert E; Brems H; Daniƫls B; De Wever I; Van Calenbergh F; Schoenaers J; Debiec-Rychter M; Gevaert O; De Raedt T; Van Den Bruel A; de Ravel T; Cichowski K; Kluwe L; Mautner V; Sciot R; Legius E
    Genes Chromosomes Cancer; 2011 Dec; 50(12):1021-32. PubMed ID: 21987445
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New Model Systems and the Development of Targeted Therapies for the Treatment of Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors.
    Williams KB; Largaespada DA
    Genes (Basel); 2020 Apr; 11(5):. PubMed ID: 32353955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microarray-based copy number analysis of neurofibromatosis type-1 (NF1)-associated malignant peripheral nerve sheath tumors reveals a role for Rho-GTPase pathway genes in NF1 tumorigenesis.
    Upadhyaya M; Spurlock G; Thomas L; Thomas NS; Richards M; Mautner VF; Cooper DN; Guha A; Yan J
    Hum Mutat; 2012 Apr; 33(4):763-76. PubMed ID: 22331697
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours.
    Bottillo I; Ahlquist T; Brekke H; Danielsen SA; van den Berg E; Mertens F; Lothe RA; Dallapiccola B
    J Pathol; 2009 Apr; 217(5):693-701. PubMed ID: 19142971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Malignant peripheral nerve sheath tumor in children: A clinicopathologic and molecular study with parallels to the adult counterpart.
    Agaram NP; Wexler LH; Chi P; Antonescu CR
    Genes Chromosomes Cancer; 2023 Mar; 62(3):131-138. PubMed ID: 36414547
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-resolution DNA copy number profiling of malignant peripheral nerve sheath tumors using targeted microarray-based comparative genomic hybridization.
    Mantripragada KK; Spurlock G; Kluwe L; Chuzhanova N; Ferner RE; Frayling IM; Dumanski JP; Guha A; Mautner V; Upadhyaya M
    Clin Cancer Res; 2008 Feb; 14(4):1015-24. PubMed ID: 18281533
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    Oppel F; Ki DH; Zimmerman MW; Ross KN; Tao T; Shi H; He S; Aster JC; Look AT
    Dis Model Mech; 2020 Aug; 13(8):. PubMed ID: 32651197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of H3K27me3 Expression Is a Highly Sensitive Marker for Sporadic and Radiation-induced MPNST.
    Prieto-Granada CN; Wiesner T; Messina JL; Jungbluth AA; Chi P; Antonescu CR
    Am J Surg Pathol; 2016 Apr; 40(4):479-89. PubMed ID: 26645727
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.