BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

935 related articles for article (PubMed ID: 28132924)

  • 1. Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts.
    Lee TM; Chang NC; Lin SZ
    Free Radic Biol Med; 2017 Mar; 104():298-310. PubMed ID: 28132924
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the PI3K/STAT3 axis modulates age-related differences in macrophage phenotype in rats with myocardial infarction.
    Lin CC; Chen SY; Lien HY; Lin SZ; Lee TM
    J Cell Mol Med; 2019 Sep; 23(9):6378-6392. PubMed ID: 31313516
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dapagliflozin attenuates arrhythmic vulnerabilities by regulating connexin43 expression via the AMPK pathway in post-infarcted rat hearts.
    Lee CC; Chen WT; Chen SY; Lee TM
    Biochem Pharmacol; 2021 Oct; 192():114674. PubMed ID: 34252408
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preconditioned adipose-derived stem cells ameliorate cardiac fibrosis by regulating macrophage polarization in infarcted rat hearts through the PI3K/STAT3 pathway.
    Lee TM; Harn HJ; Chiou TW; Chuang MH; Chen CH; Chuang CH; Lin PC; Lin SZ
    Lab Invest; 2019 May; 99(5):634-647. PubMed ID: 30683900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dual inhibition of sodium-glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction.
    Connelly KA; Zhang Y; Desjardins JF; Thai K; Gilbert RE
    Cardiovasc Diabetol; 2018 Jul; 17(1):99. PubMed ID: 29981571
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cardiac ischemia-reperfusion injury under insulin-resistant conditions: SGLT1 but not SGLT2 plays a compensatory protective role in diet-induced obesity.
    Yoshii A; Nagoshi T; Kashiwagi Y; Kimura H; Tanaka Y; Oi Y; Ito K; Yoshino T; Tanaka TD; Yoshimura M
    Cardiovasc Diabetol; 2019 Jul; 18(1):85. PubMed ID: 31262297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nicorandil regulates the macrophage skewing and ameliorates myofibroblasts by inhibition of RhoA/Rho-kinase signalling in infarcted rats.
    Lee TM; Lin SZ; Chang NC
    J Cell Mol Med; 2018 Feb; 22(2):1056-1069. PubMed ID: 29119680
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
    Niu XH; Liu RH; Lv X; He RL; Lv FZ; Wu SJ; Li XQ; Li L; Lin JF
    Inflamm Res; 2023 Apr; 72(4):879-892. PubMed ID: 36912917
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Remote transplantation of human adipose-derived stem cells induces regression of cardiac hypertrophy by regulating the macrophage polarization in spontaneously hypertensive rats.
    Lee TM; Harn HJ; Chiou TW; Chuang MH; Chen CH; Chuang CH; Lin PC; Lin SZ
    Redox Biol; 2019 Oct; 27():101170. PubMed ID: 31164286
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dapagliflozin: a sodium-glucose cotransporter 2 inhibitor, attenuates angiotensin II-induced cardiac fibrotic remodeling by regulating TGFβ1/Smad signaling.
    Zhang Y; Lin X; Chu Y; Chen X; Du H; Zhang H; Xu C; Xie H; Ruan Q; Lin J; Liu J; Zeng J; Ma K; Chai D
    Cardiovasc Diabetol; 2021 Jun; 20(1):121. PubMed ID: 34116674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin comparison with insulin shows important effects on Zn
    Olgar Y; Turan B
    Can J Physiol Pharmacol; 2019 Jun; 97(6):528-535. PubMed ID: 30444646
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation of the Effects with Saxagliptin, a DPP4 Inhibitor.
    Ye Y; Bajaj M; Yang HC; Perez-Polo JR; Birnbaum Y
    Cardiovasc Drugs Ther; 2017 Apr; 31(2):119-132. PubMed ID: 28447181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The SGLT-2 Inhibitor Dapagliflozin Has a Therapeutic Effect on Atherosclerosis in Diabetic ApoE
    Leng W; Ouyang X; Lei X; Wu M; Chen L; Wu Q; Deng W; Liang Z
    Mediators Inflamm; 2016; 2016():6305735. PubMed ID: 28104929
    [No Abstract]   [Full Text] [Related]  

  • 14. Selective SGLT2 inhibition by tofogliflozin reduces renal glucose reabsorption under hyperglycemic but not under hypo- or euglycemic conditions in rats.
    Nagata T; Fukazawa M; Honda K; Yata T; Kawai M; Yamane M; Murao N; Yamaguchi K; Kato M; Mitsui T; Suzuki Y; Ikeda S; Kawabe Y
    Am J Physiol Endocrinol Metab; 2013 Feb; 304(4):E414-23. PubMed ID: 23249697
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nonclinical toxicology assessments support the chronic safety of dapagliflozin, a first-in-class sodium-glucose cotransporter 2 inhibitor.
    Tirmenstein M; Dorr TE; Janovitz EB; Hagan D; Abell LM; Onorato JM; Whaley JM; Graziano MJ; Reilly TP
    Int J Toxicol; 2013; 32(5):336-50. PubMed ID: 24097127
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats.
    Han S; Hagan DL; Taylor JR; Xin L; Meng W; Biller SA; Wetterau JR; Washburn WN; Whaley JM
    Diabetes; 2008 Jun; 57(6):1723-9. PubMed ID: 18356408
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF-β/Smad signalling in type 2 diabetic rats.
    Tian J; Zhang M; Suo M; Liu D; Wang X; Liu M; Pan J; Jin T; An F
    J Cell Mol Med; 2021 Aug; 25(16):7642-7659. PubMed ID: 34169635
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural selectivity of human SGLT inhibitors.
    Hummel CS; Lu C; Liu J; Ghezzi C; Hirayama BA; Loo DD; Kepe V; Barrio JR; Wright EM
    Am J Physiol Cell Physiol; 2012 Jan; 302(2):C373-82. PubMed ID: 21940664
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Sodium-Glucose Cotransporter 2 with Dapagliflozin in Han: SPRD Rats with Polycystic Kidney Disease.
    Rodriguez D; Kapoor S; Edenhofer I; Segerer S; Riwanto M; Kipar A; Yang M; Mei C; Wüthrich RP
    Kidney Blood Press Res; 2015; 40(6):638-47. PubMed ID: 26698317
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of dapagliflozin on colon cancer cell [Rapid Communication].
    Saito T; Okada S; Yamada E; Shimoda Y; Osaki A; Tagaya Y; Shibusawa R; Okada J; Yamada M
    Endocr J; 2015; 62(12):1133-7. PubMed ID: 26522271
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.