BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 28134290)

  • 1. A novel HDAC inhibitor, CG200745, inhibits pancreatic cancer cell growth and overcomes gemcitabine resistance.
    Lee HS; Park SB; Kim SA; Kwon SK; Cha H; Lee DY; Ro S; Cho JM; Song SY
    Sci Rep; 2017 Jan; 7():41615. PubMed ID: 28134290
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CG200745, an HDAC inhibitor, induces anti-tumour effects in cholangiocarcinoma cell lines via miRNAs targeting the Hippo pathway.
    Jung DE; Park SB; Kim K; Kim C; Song SY
    Sci Rep; 2017 Sep; 7(1):10921. PubMed ID: 28883618
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XL.
    Hwang JJ; Kim YS; Kim T; Kim MJ; Jeong IG; Lee JH; Choi J; Jang S; Ro S; Kim CS
    Invest New Drugs; 2012 Aug; 30(4):1434-42. PubMed ID: 21773733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells.
    Oh ET; Park MT; Choi BH; Ro S; Choi EK; Jeong SY; Park HJ
    Invest New Drugs; 2012 Apr; 30(2):435-42. PubMed ID: 20978925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer.
    Chun SG; Zhou W; Yee NS
    Cancer Biol Ther; 2009 Jul; 8(14):1328-39. PubMed ID: 19421011
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors.
    Samulitis BK; Pond KW; Pond E; Cress AE; Patel H; Wisner L; Patel C; Dorr RT; Landowski TH
    Cancer Biol Ther; 2015; 16(1):43-51. PubMed ID: 25485960
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer.
    Dovzhanskiy DI; Arnold SM; Hackert T; Oehme I; Witt O; Felix K; Giese N; Werner J
    BMC Cancer; 2012 Jun; 12():226. PubMed ID: 22681698
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells.
    Chen MC; Chen CH; Wang JC; Tsai AC; Liou JP; Pan SL; Teng CM
    Cell Death Dis; 2013 Sep; 4(9):e810. PubMed ID: 24052078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine.
    Donadelli M; Costanzo C; Beghelli S; Scupoli MT; Dandrea M; Bonora A; Piacentini P; Budillon A; Caraglia M; Scarpa A; Palmieri M
    Biochim Biophys Acta; 2007 Jul; 1773(7):1095-106. PubMed ID: 17555830
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of caspase mediated apoptosis and down-regulation of nuclear factor-κB and Akt signaling are involved in the synergistic antitumor effect of gemcitabine and the histone deacetylase inhibitor trichostatin A in human bladder cancer cells.
    Jeon HG; Yoon CY; Yu JH; Park MJ; Lee JE; Jeong SJ; Hong SK; Byun SS; Lee SE
    J Urol; 2011 Nov; 186(5):2084-93. PubMed ID: 21944112
    [TBL] [Abstract][Full Text] [Related]  

  • 11. First-in-human study of the toxicity, pharmacokinetics, and pharmacodynamics of CG200745, a pan-HDAC inhibitor, in patients with refractory solid malignancies.
    Kim KP; Park SJ; Kim JE; Hong YS; Lee JL; Bae KS; Cha H; Kwon SK; Ro S; Cho J; Kim TW
    Invest New Drugs; 2015 Oct; 33(5):1048-57. PubMed ID: 26076682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer.
    Venkatasubbarao K; Peterson L; Zhao S; Hill P; Cao L; Zhou Q; Nawrocki ST; Freeman JW
    Mol Cancer; 2013 Sep; 12(1):104. PubMed ID: 24025152
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone deacetylase inhibitor CG200745 ameliorates high-fat diet-induced hypertension via inhibition of angiotensin II production.
    Yoon GE; Jung JK; Lee YH; Jang BC; In Kim J
    Naunyn Schmiedebergs Arch Pharmacol; 2020 Mar; 393(3):491-500. PubMed ID: 31655853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective disruption of rb-raf-1 kinase interaction inhibits pancreatic adenocarcinoma growth irrespective of gemcitabine sensitivity.
    Treviño JG; Verma M; Singh S; Pillai S; Zhang D; Pernazza D; Sebti SM; Lawrence NJ; Centeno BA; Chellappan SP
    Mol Cancer Ther; 2013 Dec; 12(12):2722-34. PubMed ID: 24107447
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces growth inhibition and enhances gemcitabine-induced cell death in pancreatic cancer.
    Arnold NB; Arkus N; Gunn J; Korc M
    Clin Cancer Res; 2007 Jan; 13(1):18-26. PubMed ID: 17200334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epigenetic modulation and attacking the hedgehog pathway: potentially synergistic therapeutic targets for pancreatic cancer.
    Freeman JW; Wang Y; Giles FJ
    Cancer Biol Ther; 2009 Jul; 8(14):1340-2. PubMed ID: 19440037
    [No Abstract]   [Full Text] [Related]  

  • 17. The therapeutic effect of histone deacetylase inhibitor PCI-24781 on gallbladder carcinoma in BK5.erbB2 mice.
    Kitamura T; Connolly K; Ruffino L; Ajiki T; Lueckgen A; DiGiovanni J; Kiguchi K
    J Hepatol; 2012 Jul; 57(1):84-91. PubMed ID: 22326466
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SAHA, an HDAC inhibitor, overcomes erlotinib resistance in human pancreatic cancer cells by modulating E-cadherin.
    Park SJ; Kim SM; Moon JH; Kim JH; Shin JS; Hong SW; Shin YJ; Lee DH; Lee EY; Hwang IY; Kim JE; Kim KP; Hong YS; Lee WK; Choi EK; Lee JS; Jin DH; Kim TW
    Tumour Biol; 2016 Apr; 37(4):4323-30. PubMed ID: 26493999
    [TBL] [Abstract][Full Text] [Related]  

  • 19. {Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.
    Kunnumakkara AB; Sung B; Ravindran J; Diagaradjane P; Deorukhkar A; Dey S; Koca C; Yadav VR; Tong Z; Gelovani JG; Guha S; Krishnan S; Aggarwal BB
    Cancer Res; 2010 Nov; 70(21):8695-705. PubMed ID: 20864511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epigenetic modulation with HDAC inhibitor CG200745 induces anti-proliferation in non-small cell lung cancer cells.
    Chun SM; Lee JY; Choi J; Lee JH; Hwang JJ; Kim CS; Suh YA; Jang SJ
    PLoS One; 2015; 10(3):e0119379. PubMed ID: 25781604
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.