251 related articles for article (PubMed ID: 28134508)
1. Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.
McGovern-Gooch KR; Mahajani NS; Garagozzo A; Schramm AJ; Hannah LG; Sieburg MA; Chisholm JD; Hougland JL
Biochemistry; 2017 Feb; 56(7):919-931. PubMed ID: 28134508
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity analysis of human ghrelin O-acyltransferase reveals chemical determinants of ghrelin selectivity and acyl group recognition.
Darling JE; Zhao F; Loftus RJ; Patton LM; Gibbs RA; Hougland JL
Biochemistry; 2015 Feb; 54(4):1100-10. PubMed ID: 25562443
[TBL] [Abstract][Full Text] [Related]
3. A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase.
Darling JE; Prybolsky EP; Sieburg M; Hougland JL
Anal Biochem; 2013 Jun; 437(1):68-76. PubMed ID: 23453974
[TBL] [Abstract][Full Text] [Related]
4. Biochemical Assays for Ghrelin Acylation and Inhibition of Ghrelin O-Acyltransferase.
Sieburg MA; Cleverdon ER; Hougland JL
Methods Mol Biol; 2019; 2009():227-241. PubMed ID: 31152408
[TBL] [Abstract][Full Text] [Related]
5. Ghrelin octanoylation by ghrelin
Davis TR; Pierce MR; Novak SX; Hougland JL
Open Biol; 2021 Jul; 11(7):210080. PubMed ID: 34315274
[TBL] [Abstract][Full Text] [Related]
6. Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation.
Cleverdon ER; Davis TR; Hougland JL
Bioorg Chem; 2018 Sep; 79():98-106. PubMed ID: 29738973
[TBL] [Abstract][Full Text] [Related]
7. A small molecule antagonist of ghrelin O-acyltransferase (GOAT).
Garner AL; Janda KD
Chem Commun (Camb); 2011 Jul; 47(26):7512-4. PubMed ID: 21594284
[TBL] [Abstract][Full Text] [Related]
8. A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups.
Zhao F; Darling JE; Gibbs RA; Hougland JL
Bioorg Med Chem Lett; 2015 Jul; 25(14):2800-3. PubMed ID: 26009163
[TBL] [Abstract][Full Text] [Related]
9. Ghrelin O-acyltransferase assays and inhibition.
Taylor MS; Hwang Y; Hsiao PY; Boeke JD; Cole PA
Methods Enzymol; 2012; 514():205-28. PubMed ID: 22975055
[TBL] [Abstract][Full Text] [Related]
10. Ghrelin octanoylation by ghrelin
Hougland JL
Biochem Soc Trans; 2019 Feb; 47(1):169-178. PubMed ID: 30626708
[TBL] [Abstract][Full Text] [Related]
11. An overview of ghrelin
Moose JE; Leets KA; Mate NA; Chisholm JD; Hougland JL
Expert Opin Ther Pat; 2020 Aug; 30(8):581-593. PubMed ID: 32564644
[TBL] [Abstract][Full Text] [Related]
12. Membrane bound O-acyltransferases and their inhibitors.
Masumoto N; Lanyon-Hogg T; Rodgers UR; Konitsiotis AD; Magee AI; Tate EW
Biochem Soc Trans; 2015 Apr; 43(2):246-52. PubMed ID: 25849925
[TBL] [Abstract][Full Text] [Related]
13. GOAT: the master switch for the ghrelin system?
Romero A; Kirchner H; Heppner K; Pfluger PT; Tschöp MH; Nogueiras R
Eur J Endocrinol; 2010 Jul; 163(1):1-8. PubMed ID: 20421334
[TBL] [Abstract][Full Text] [Related]
14. Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase.
Taylor MS; Ruch TR; Hsiao PY; Hwang Y; Zhang P; Dai L; Huang CRL; Berndsen CE; Kim MS; Pandey A; Wolberger C; Marmorstein R; Machamer C; Boeke JD; Cole PA
J Biol Chem; 2013 Nov; 288(45):32211-32228. PubMed ID: 24045953
[TBL] [Abstract][Full Text] [Related]
15. Ghrelin O-acyltransferase (GOAT) and energy metabolism.
Li Z; Mulholland M; Zhang W
Sci China Life Sci; 2016 Mar; 59(3):281-91. PubMed ID: 26732975
[TBL] [Abstract][Full Text] [Related]
16. Discovery of ghrelin o-acyltransferase.
Mohan H; Unniappan S
Endocr Dev; 2013; 25():16-24. PubMed ID: 23652388
[TBL] [Abstract][Full Text] [Related]
17. The ghrelin
Campaña MB; Irudayanathan FJ; Davis TR; McGovern-Gooch KR; Loftus R; Ashkar M; Escoffery N; Navarro M; Sieburg MA; Nangia S; Hougland JL
J Biol Chem; 2019 Sep; 294(39):14166-14174. PubMed ID: 31413115
[TBL] [Abstract][Full Text] [Related]
18. In Search of Small Molecules That Selectively Inhibit MBOAT4.
Murzinski ES; Saha I; Ding H; Strugatsky D; Hollibaugh RA; Liu H; Tontonoz P; Harran PG
Molecules; 2021 Dec; 26(24):. PubMed ID: 34946685
[TBL] [Abstract][Full Text] [Related]
19. Shedding light on the ghrelin/GOAT metabolism saga.
Garner AL; Janda KD
Chembiochem; 2011 Mar; 12(4):523-5. PubMed ID: 21254317
[TBL] [Abstract][Full Text] [Related]
20. Ghrelin acylation and metabolic control.
Al Massadi O; Tschöp MH; Tong J
Peptides; 2011 Nov; 32(11):2301-8. PubMed ID: 21893140
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]