BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 28134932)

  • 1. Eukaryotic Rad50 functions as a rod-shaped dimer.
    Park YB; Hohl M; Padjasek M; Jeong E; Jin KS; Krężel A; Petrini JH; Cho Y
    Nat Struct Mol Biol; 2017 Mar; 24(3):248-257. PubMed ID: 28134932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.
    Hopfner KP; Craig L; Moncalian G; Zinkel RA; Usui T; Owen BA; Karcher A; Henderson B; Bodmer JL; McMurray CT; Carney JP; Petrini JH; Tainer JA
    Nature; 2002 Aug; 418(6897):562-6. PubMed ID: 12152085
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge.
    Tatebe H; Lim CT; Konno H; Shiozaki K; Shinohara A; Uchihashi T; Furukohri A
    Nat Commun; 2020 Jan; 11(1):370. PubMed ID: 31953386
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.
    Lammens K; Bemeleit DJ; Möckel C; Clausing E; Schele A; Hartung S; Schiller CB; Lucas M; Angermüller C; Söding J; Strässer K; Hopfner KP
    Cell; 2011 Apr; 145(1):54-66. PubMed ID: 21458667
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain.
    Barfoot T; Herdendorf TJ; Behning BR; Stohr BA; Gao Y; Kreuzer KN; Nelson SW
    J Biol Chem; 2015 Sep; 290(39):23905-15. PubMed ID: 26242734
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of the Rad50 DNA double-strand break repair protein in complex with DNA.
    Rojowska A; Lammens K; Seifert FU; Direnberger C; Feldmann H; Hopfner KP
    EMBO J; 2014 Dec; 33(23):2847-59. PubMed ID: 25349191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interdependence of the rad50 hook and globular domain functions.
    Hohl M; Kochańczyk T; Tous C; Aguilera A; Krężel A; Petrini JH
    Mol Cell; 2015 Feb; 57(3):479-91. PubMed ID: 25601756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
    Deshpande RA; Williams GJ; Limbo O; Williams RS; Kuhnlein J; Lee JH; Classen S; Guenther G; Russell P; Tainer JA; Paull TT
    EMBO J; 2014 Mar; 33(5):482-500. PubMed ID: 24493214
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A rod conformation of the Pyrococcus furiosus Rad50 coiled coil.
    Soh YM; Basquin J; Gruber S
    Proteins; 2021 Feb; 89(2):251-255. PubMed ID: 32875643
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA.
    Moreno-Herrero F; de Jager M; Dekker NH; Kanaar R; Wyman C; Dekker C
    Nature; 2005 Sep; 437(7057):440-3. PubMed ID: 16163361
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mre11-Rad50 complex crystals suggest molecular calisthenics.
    Wyman C; Lebbink J; Kanaar R
    DNA Repair (Amst); 2011 Oct; 10(10):1066-70. PubMed ID: 21893433
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.
    Lafrance-Vanasse J; Williams GJ; Tainer JA
    Prog Biophys Mol Biol; 2015 Mar; 117(2-3):182-193. PubMed ID: 25576492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dimerization of the Rad50 protein is independent of the conserved hook domain.
    Cahill D; Carney JP
    Mutagenesis; 2007 Jul; 22(4):269-74. PubMed ID: 17426050
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair.
    Boswell ZK; Rahman S; Canny MD; Latham MP
    Sci Rep; 2018 Jan; 8(1):1639. PubMed ID: 29374232
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Rad50 hook domain is a critical determinant of Mre11 complex functions.
    Wiltzius JJ; Hohl M; Fleming JC; Petrini JH
    Nat Struct Mol Biol; 2005 May; 12(5):403-7. PubMed ID: 15852023
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.
    Roset R; Inagaki A; Hohl M; Brenet F; Lafrance-Vanasse J; Lange J; Scandura JM; Tainer JA; Keeney S; Petrini JH
    Genes Dev; 2014 Mar; 28(5):451-62. PubMed ID: 24532689
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex.
    Chen YJ; Chuang YC; Chuang CN; Cheng YH; Chang CR; Leng CH; Wang TF
    Nucleic Acids Res; 2016 Mar; 44(5):2199-213. PubMed ID: 26743002
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.
    Bhaskara V; Dupré A; Lengsfeld B; Hopkins BB; Chan A; Lee JH; Zhang X; Gautier J; Zakian V; Paull TT
    Mol Cell; 2007 Mar; 25(5):647-61. PubMed ID: 17349953
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy.
    Chang L; Huang J; Wang K; Li J; Yan R; Zhu L; Ye J; Wu X; Zhuang S; Li D; Zhang G
    BMC Cancer; 2016 Mar; 16():190. PubMed ID: 26951044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.