388 related articles for article (PubMed ID: 28135635)
21. Allosteric approaches to the targeting of G-protein-coupled receptors for novel drug discovery: a critical assessment.
Raddatz R; Schaffhauser H; Marino MJ
Biochem Pharmacol; 2007 Aug; 74(3):383-91. PubMed ID: 17572390
[TBL] [Abstract][Full Text] [Related]
22. Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors.
Lindsley CW; Emmitte KA; Hopkins CR; Bridges TM; Gregory KJ; Niswender CM; Conn PJ
Chem Rev; 2016 Jun; 116(11):6707-41. PubMed ID: 26882314
[TBL] [Abstract][Full Text] [Related]
23. High-Throughput Screening for Allosteric Modulators of GPCRs.
Bertekap RL; Burford NT; Li Z; Alt A
Methods Mol Biol; 2015; 1335():223-40. PubMed ID: 26260604
[TBL] [Abstract][Full Text] [Related]
24. Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry.
Fronik P; Gaiser BI; Sejer Pedersen D
J Med Chem; 2017 May; 60(10):4126-4134. PubMed ID: 28140580
[TBL] [Abstract][Full Text] [Related]
25. Pharmacologically targeting intracellular allosteric sites of GPCRs for drug discovery.
Zhang M; Lan X; Li X; Lu S
Drug Discov Today; 2023 Dec; 28(12):103803. PubMed ID: 37852356
[TBL] [Abstract][Full Text] [Related]
26. The Retinoid and Non-Retinoid Ligands of the Rod Visual G Protein-Coupled Receptor.
Ortega JT; Jastrzebska B
Int J Mol Sci; 2019 Dec; 20(24):. PubMed ID: 31835521
[TBL] [Abstract][Full Text] [Related]
27. Structural Basis for Allosteric Modulation of Class B G Protein-Coupled Receptors.
Wootten D; Miller LJ
Annu Rev Pharmacol Toxicol; 2020 Jan; 60():89-107. PubMed ID: 31454292
[TBL] [Abstract][Full Text] [Related]
28. Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.
Conn PJ; Christopoulos A; Lindsley CW
Nat Rev Drug Discov; 2009 Jan; 8(1):41-54. PubMed ID: 19116626
[TBL] [Abstract][Full Text] [Related]
29. The role of GPCRs in neurodegenerative diseases: avenues for therapeutic intervention.
Huang Y; Todd N; Thathiah A
Curr Opin Pharmacol; 2017 Feb; 32():96-110. PubMed ID: 28288370
[TBL] [Abstract][Full Text] [Related]
30. Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.
Lu S; Zhang J
J Med Chem; 2019 Jan; 62(1):24-45. PubMed ID: 29457894
[TBL] [Abstract][Full Text] [Related]
31. Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts.
Wold EA; Chen J; Cunningham KA; Zhou J
J Med Chem; 2019 Jan; 62(1):88-127. PubMed ID: 30106578
[TBL] [Abstract][Full Text] [Related]
32. Design of multivalent ligand targeting G-protein-coupled receptors.
Liu Z; Zhang J; Zhang A
Curr Pharm Des; 2009; 15(6):682-718. PubMed ID: 19199990
[TBL] [Abstract][Full Text] [Related]
33. Advances in G protein-coupled receptor allostery: from function to structure.
Christopoulos A
Mol Pharmacol; 2014 Nov; 86(5):463-78. PubMed ID: 25061106
[TBL] [Abstract][Full Text] [Related]
34. Molecular insights into allosteric modulation of Class C G protein-coupled receptors.
Leach K; Gregory KJ
Pharmacol Res; 2017 Feb; 116():105-118. PubMed ID: 27965032
[TBL] [Abstract][Full Text] [Related]
35. G-protein-coupled receptors: from classical modes of modulation to allosteric mechanisms.
Bridges TM; Lindsley CW
ACS Chem Biol; 2008 Sep; 3(9):530-41. PubMed ID: 18652471
[TBL] [Abstract][Full Text] [Related]
36. GPCR drug discovery-moving beyond the orthosteric to the allosteric domain.
Felder CC
Adv Pharmacol; 2019; 86():1-20. PubMed ID: 31378249
[TBL] [Abstract][Full Text] [Related]
37. Quantitative analysis of receptor allosterism and its implication for drug discovery.
Zhang R; Kavana M
Expert Opin Drug Discov; 2015 Jul; 10(7):763-80. PubMed ID: 25927503
[TBL] [Abstract][Full Text] [Related]
38. Wandering beyond small molecules: peptides as allosteric protein modulators.
Mannes M; Martin C; Menet C; Ballet S
Trends Pharmacol Sci; 2022 May; 43(5):406-423. PubMed ID: 34857409
[TBL] [Abstract][Full Text] [Related]
39. Allosteric modulation of G-protein coupled receptors.
Jensen AA; Spalding TA
Eur J Pharm Sci; 2004 Mar; 21(4):407-20. PubMed ID: 14998571
[TBL] [Abstract][Full Text] [Related]
40. Analyzing biased responses of GPCR ligands.
Benredjem B; Dallaire P; Pineyro G
Curr Opin Pharmacol; 2017 Feb; 32():71-76. PubMed ID: 27930943
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
