BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

632 related articles for article (PubMed ID: 28140580)

  • 21. Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.
    Bartuzi D; Kaczor AA; Matosiuk D
    Methods Mol Biol; 2018; 1705():297-319. PubMed ID: 29188568
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Is there a common allosteric binding site for G-protein coupled receptors?
    Malik F; Li Z
    J Comput Aided Mol Des; 2022 Jun; 36(6):405-413. PubMed ID: 35507106
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric/allosteric ligand.
    Valant C; Gregory KJ; Hall NE; Scammells PJ; Lew MJ; Sexton PM; Christopoulos A
    J Biol Chem; 2008 Oct; 283(43):29312-21. PubMed ID: 18723515
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.
    Janero DR; Thakur GA
    Expert Opin Drug Discov; 2016 Dec; 11(12):1223-1237. PubMed ID: 27712124
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Allosteric Modulators of the Class A G Protein Coupled Receptors.
    Tschammer N
    Adv Exp Med Biol; 2016; 917():185-207. PubMed ID: 27236557
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Covalent allosteric modulation: An emerging strategy for GPCRs drug discovery.
    Bian Y; Jun JJ; Cuyler J; Xie XQ
    Eur J Med Chem; 2020 Nov; 206():112690. PubMed ID: 32818870
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel Allosteric Modulators of G Protein-coupled Receptors.
    Gentry PR; Sexton PM; Christopoulos A
    J Biol Chem; 2015 Aug; 290(32):19478-88. PubMed ID: 26100627
    [TBL] [Abstract][Full Text] [Related]  

  • 28. GPCR Allosteric Modulator Discovery.
    Wu Y; Tong J; Ding K; Zhou Q; Zhao S
    Adv Exp Med Biol; 2019; 1163():225-251. PubMed ID: 31707706
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Emerging opportunities for allosteric modulation of G-protein coupled receptors.
    Wang CI; Lewis RJ
    Biochem Pharmacol; 2013 Jan; 85(2):153-62. PubMed ID: 22975406
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs.
    Hudson BD; Ulven T; Milligan G
    Curr Top Med Chem; 2013; 13(1):14-25. PubMed ID: 23409763
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Allosteric modulation of G protein-coupled receptors.
    May LT; Leach K; Sexton PM; Christopoulos A
    Annu Rev Pharmacol Toxicol; 2007; 47():1-51. PubMed ID: 17009927
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The Dynamic Process of Drug-GPCR Binding at Either Orthosteric or Allosteric Sites Evaluated by Metadynamics.
    Schneider S; Provasi D; Filizola M
    Methods Mol Biol; 2015; 1335():277-94. PubMed ID: 26260607
    [TBL] [Abstract][Full Text] [Related]  

  • 33. G protein-coupled receptors (GPCRs): advances in structures, mechanisms, and drug discovery.
    Zhang M; Chen T; Lu X; Lan X; Chen Z; Lu S
    Signal Transduct Target Ther; 2024 Apr; 9(1):88. PubMed ID: 38594257
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Surface plasmon resonance analysis of seven-transmembrane receptors.
    Aristotelous T; Hopkins AL; Navratilova I
    Methods Enzymol; 2015; 556():499-525. PubMed ID: 25857797
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Opioid Ligands Addressing Unconventional Binding Sites and More Than One Opioid Receptor Subtype.
    Drakopoulos A; Moianos D; Prifti GM; Zoidis G; Decker M
    ChemMedChem; 2022 Jul; 17(14):e202200169. PubMed ID: 35560796
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Unmasking allosteric-binding sites: novel targets for GPCR drug discovery.
    Casadó-Anguera V; Casadó V
    Expert Opin Drug Discov; 2022 Aug; 17(8):897-923. PubMed ID: 35649692
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Functional and structural perspectives on allosteric modulation of GPCRs.
    Langmead CJ; Christopoulos A
    Curr Opin Cell Biol; 2014 Apr; 27():94-101. PubMed ID: 24680434
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Emerging paradigms in GPCR allostery: implications for drug discovery.
    Wootten D; Christopoulos A; Sexton PM
    Nat Rev Drug Discov; 2013 Aug; 12(8):630-44. PubMed ID: 23903222
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structures of G protein-coupled receptors reveal new opportunities for drug discovery.
    Cooke RM; Brown AJ; Marshall FH; Mason JS
    Drug Discov Today; 2015 Nov; 20(11):1355-64. PubMed ID: 26303408
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The First Negative Allosteric Modulator for Dopamine D
    Rossi M; Fasciani I; Marampon F; Maggio R; Scarselli M
    Mol Pharmacol; 2017 Jun; 91(6):586-594. PubMed ID: 28265019
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 32.