BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 28143890)

  • 1. Localization of mTORC2 activity inside cells.
    Ebner M; Sinkovics B; Szczygieł M; Ribeiro DW; Yudushkin I
    J Cell Biol; 2017 Feb; 216(2):343-353. PubMed ID: 28143890
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation.
    Yang G; Murashige DS; Humphrey SJ; James DE
    Cell Rep; 2015 Aug; 12(6):937-43. PubMed ID: 26235620
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.
    Chen CH; Kiyan V; Zhylkibayev AA; Kazyken D; Bulgakova O; Page KE; Bersimbaev RI; Spooner E; Sarbassov DD
    J Biol Chem; 2013 Sep; 288(38):27019-27030. PubMed ID: 23928304
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.
    Liu P; Gan W; Chin YR; Ogura K; Guo J; Zhang J; Wang B; Blenis J; Cantley LC; Toker A; Su B; Wei W
    Cancer Discov; 2015 Nov; 5(11):1194-209. PubMed ID: 26293922
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH; Park YH; Kwon JH; Lee JH; Kim IY
    Biochim Biophys Acta; 2013 Oct; 1833(10):2135-42. PubMed ID: 23680186
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
    Lee D; Sykes SM; Kalaitzidis D; Lane AA; Kfoury Y; Raaijmakers MH; Wang YH; Armstrong SA; Scadden DT
    Stem Cell Reports; 2014 Nov; 3(5):832-40. PubMed ID: 25418727
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic reticulum is a main localization site of mTORC2.
    Boulbés DR; Shaiken T; Sarbassov dos D
    Biochem Biophys Res Commun; 2011 Sep; 413(1):46-52. PubMed ID: 21867682
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
    Liu P; Gan W; Inuzuka H; Lazorchak AS; Gao D; Arojo O; Liu D; Wan L; Zhai B; Yu Y; Yuan M; Kim BM; Shaik S; Menon S; Gygi SP; Lee TH; Asara JM; Manning BD; Blenis J; Su B; Wei W
    Nat Cell Biol; 2013 Nov; 15(11):1340-50. PubMed ID: 24161930
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IKK interacts with rictor and regulates mTORC2.
    Xu Y; Lai E; Liu J; Lin J; Yang C; Jia C; Li Y; Bai X; Li M
    Cell Signal; 2013 Nov; 25(11):2239-45. PubMed ID: 23872070
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The SIN1-PH Domain Connects mTORC2 to PI3K.
    Yuan HX; Guan KL
    Cancer Discov; 2015 Nov; 5(11):1127-9. PubMed ID: 26526694
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
    J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology.
    Betz C; Stracka D; Prescianotto-Baschong C; Frieden M; Demaurex N; Hall MN
    Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12526-34. PubMed ID: 23852728
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.
    Luo Y; Liu L; Wu Y; Singh K; Su B; Zhang N; Liu X; Shen Y; Huang S
    Oncotarget; 2015 Feb; 6(6):4286-98. PubMed ID: 25738366
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression.
    Yasuda K; Takahashi M; Mori N
    PLoS One; 2015; 10(11):e0142943. PubMed ID: 26600389
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein.
    Glidden EJ; Gray LG; Vemuru S; Li D; Harris TE; Mayo MW
    J Biol Chem; 2012 Jan; 287(1):581-588. PubMed ID: 22084251
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation.
    Dalle Pezze P; Sonntag AG; Thien A; Prentzell MT; Gödel M; Fischer S; Neumann-Haefelin E; Huber TB; Baumeister R; Shanley DP; Thedieck K
    Sci Signal; 2012 Mar; 5(217):ra25. PubMed ID: 22457331
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.
    Wang B; Jie Z; Joo D; Ordureau A; Liu P; Gan W; Guo J; Zhang J; North BJ; Dai X; Cheng X; Bian X; Zhang L; Harper JW; Sun SC; Wei W
    Nature; 2017 May; 545(7654):365-369. PubMed ID: 28489822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
    Zhang J; Xu K; Liu P; Geng Y; Wang B; Gan W; Guo J; Wu F; Chin YR; Berrios C; Lien EC; Toker A; DeCaprio JA; Sicinski P; Wei W
    Mol Cell; 2016 Jun; 62(6):929-942. PubMed ID: 27237051
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
    Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R
    Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells
    Zheng B; Wang J; Tang L; Tan C; Zhao Z; Xiao Y; Ge R; Zhu D
    Int J Biol Sci; 2017; 13(1):110-121. PubMed ID: 28123351
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.