BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 28147308)

  • 1. Mono-functionalized glycosylated platinum(IV) complexes possessed both pH and redox dual-responsive properties: Exhibited enhanced safety and preferentially accumulated in cancer cells in vitro and in vivo.
    Ma J; Yang X; Hao W; Huang Z; Wang X; Wang PG
    Eur J Med Chem; 2017 Mar; 128():45-55. PubMed ID: 28147308
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of a novel series of glycosylated platinum(iv) complexes as antitumor agents.
    Wang Q; Huang Z; Ma J; Lu X; Zhang L; Wang X; George Wang P
    Dalton Trans; 2016 Jun; 45(25):10366-74. PubMed ID: 27252024
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic and biological characteristics of different sugar conjugated 2-methyl malonatoplatinum(II) complexes as new tumor targeting agents.
    Gao X; Liu S; Shi Y; Huang Z; Mi Y; Mi Q; Yang J; Gao Q
    Eur J Med Chem; 2017 Jan; 125():372-384. PubMed ID: 27688191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding Properties for Drug Delivery.
    Ma J; Wang Q; Huang Z; Yang X; Nie Q; Hao W; Wang PG; Wang X
    J Med Chem; 2017 Jul; 60(13):5736-5748. PubMed ID: 28603992
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glucose-conjugated platinum(IV) complexes as tumor-targeting agents: design, synthesis and biological evaluation.
    Wang H; Yang X; Zhao C; Wang PG; Wang X
    Bioorg Med Chem; 2019 Apr; 27(8):1639-1645. PubMed ID: 30852077
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glycosylated platinum(iv) prodrugs demonstrated significant therapeutic efficacy in cancer cells and minimized side-effects.
    Ma J; Wang Q; Yang X; Hao W; Huang Z; Zhang J; Wang X; Wang PG
    Dalton Trans; 2016 Jul; 45(29):11830-8. PubMed ID: 27373800
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human Serum Albumin Conjugated Nanoparticles for pH and Redox-Responsive Delivery of a Prodrug of Cisplatin.
    Shi H; Cheng Q; Yuan S; Ding X; Liu Y
    Chemistry; 2015 Nov; 21(46):16547-54. PubMed ID: 26405808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R,2R-diaminocyclohexane platinum(IV) complexes.
    Siddik ZH; al-Baker S; Thai G; Khokhar AR
    Anticancer Drug Des; 1994 Apr; 9(2):139-51. PubMed ID: 8166929
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models.
    Göschl S; Schreiber-Brynzak E; Pichler V; Cseh K; Heffeter P; Jungwirth U; Jakupec MA; Berger W; Keppler BK
    Metallomics; 2017 Mar; 9(3):309-322. PubMed ID: 28205649
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug.
    Kelland LR; Abel G; McKeage MJ; Jones M; Goddard PM; Valenti M; Murrer BA; Harrap KR
    Cancer Res; 1993 Jun; 53(11):2581-6. PubMed ID: 8388318
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantitative measurement of the reduction of platinum(IV) complexes using X-ray absorption near-edge spectroscopy (XANES).
    Hall MD; Daly HL; Zhang JZ; Zhang M; Alderden RA; Pursche D; Foran GJ; Hambley TW
    Metallomics; 2012 Jun; 4(6):568-75. PubMed ID: 22569908
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Construction of Dual Stimuli-Responsive Platinum(IV) Hybrids with NQO1 Targeting Ability and Overcoming Cisplatin Resistance.
    Fang L; Qin X; Zhao J; Gou S
    Inorg Chem; 2019 Feb; 58(3):2191-2200. PubMed ID: 30657321
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Galactose conjugated platinum(II) complex targeting the Warburg effect for treatment of non-small cell lung cancer and colon cancer.
    Wu M; Li H; Liu R; Gao X; Zhang M; Liu P; Fu Z; Yang J; Zhang-Negrerie D; Gao Q
    Eur J Med Chem; 2016 Mar; 110():32-42. PubMed ID: 26807543
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combination of 7-hydroxycoumarin in a platinum(IV) complex derived from cisplatin enhanced cytotoxicity with multiple mechanisms of action.
    Hua W; Zhao J; Hu W; Gou S
    J Inorg Biochem; 2018 Sep; 186():17-23. PubMed ID: 29807243
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel trans-platinum coordination complex possessing in vitro and in vivo antitumor activity.
    Kelland LR; Barnard CF; Mellish KJ; Jones M; Goddard PM; Valenti M; Bryant A; Murrer BA; Harrap KR
    Cancer Res; 1994 Nov; 54(21):5618-22. PubMed ID: 7923207
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands.
    Novohradsky V; Zerzankova L; Stepankova J; Vrana O; Raveendran R; Gibson D; Kasparkova J; Brabec V
    J Inorg Biochem; 2014 Nov; 140():72-9. PubMed ID: 25063910
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel bis-platinum complexes endowed with an improved pharmacological profile.
    Gatti L; Perego P; Leone R; Apostoli P; Carenini N; Corna E; Allievi C; Bastrup U; De Munari S; Di Giovine S; Nicoli P; Grugni M; Natangelo M; Pardi G; Pezzoni G; Singer JW; Zunino F
    Mol Pharm; 2010 Feb; 7(1):207-16. PubMed ID: 19919086
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of antitumor azolato-bridged dinuclear platinum(ii) complexes with in vivo antitumor efficacy and unique in vitro cytotoxicity profiles.
    Komeda S; Takayama H; Suzuki T; Odani A; Yamori T; Chikuma M
    Metallomics; 2013 May; 5(5):461-8. PubMed ID: 23608770
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor activity of a new platinum(II) complex with low nephrotoxicity and genotoxicity.
    Marzano C; Bettio F; Baccichetti F; Trevisan A; Giovagnini L; Fregona D
    Chem Biol Interact; 2004 Jun; 148(1-2):37-48. PubMed ID: 15223355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reversal of cisplatin resistance in human gastric cancer cells by a wogonin-conjugated Pt(IV) prodrug via attenuating Casein Kinase 2-mediated Nuclear Factor-κB pathways.
    Chen F; Qin X; Xu G; Gou S; Jin X
    Biochem Pharmacol; 2017 Jul; 135():50-68. PubMed ID: 28288821
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.