121 related articles for article (PubMed ID: 28152427)
1. Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.
Elkamhawy A; Park JE; Hassan AHE; Ra H; Pae AN; Lee J; Park BG; Moon B; Park HM; Roh EJ
Eur J Med Chem; 2017 Mar; 128():56-69. PubMed ID: 28152427
[TBL] [Abstract][Full Text] [Related]
2. Pyrazinyl ureas revisited: 1-(3-(Benzyloxy)pyrazin-2-yl)-3-(3,4-dichlorophenyl)urea, a new blocker of Aβ-induced mPTP opening for Alzheimer's disease.
Elkamhawy A; Park JE; Hassan AHE; Pae AN; Lee J; Paik S; Park BG; Roh EJ
Eur J Med Chem; 2018 Sep; 157():268-278. PubMed ID: 30098482
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease.
Elkamhawy A; Park JE; Hassan AHE; Pae AN; Lee J; Park BG; Roh EJ
Eur J Med Chem; 2018 Jan; 144():529-543. PubMed ID: 29288949
[TBL] [Abstract][Full Text] [Related]
4. Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: design, synthesis, and molecular docking study.
Elkamhawy A; Lee J; Park BG; Park I; Pae AN; Roh EJ
Eur J Med Chem; 2014 Sep; 84():466-75. PubMed ID: 25050879
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-β-induced toxicity.
Park JE; Elkamhawy A; Hassan AHE; Pae AN; Lee J; Paik S; Park BG; Roh EJ
Eur J Med Chem; 2017 Dec; 141():322-334. PubMed ID: 29031076
[TBL] [Abstract][Full Text] [Related]
6. Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction.
Park I; Londhe AM; Lim JW; Park BG; Jung SY; Lee JY; Lim SM; No KT; Lee J; Pae AN
J Comput Aided Mol Des; 2017 Oct; 31(10):929-941. PubMed ID: 28913661
[TBL] [Abstract][Full Text] [Related]
7. Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons.
Guo L; Du H; Yan S; Wu X; McKhann GM; Chen JX; Yan SS
PLoS One; 2013; 8(1):e54914. PubMed ID: 23382999
[TBL] [Abstract][Full Text] [Related]
8. CypD-mPTP axis regulates mitochondrial functions contributing to osteogenic dysfunction of MC3T3-E1 cells in inflammation.
Gan X; Zhang L; Liu B; Zhu Z; He Y; Chen J; Zhu J; Yu H
J Physiol Biochem; 2018 Aug; 74(3):395-402. PubMed ID: 29679227
[TBL] [Abstract][Full Text] [Related]
9. Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis.
Shore ER; Awais M; Kershaw NM; Gibson RR; Pandalaneni S; Latawiec D; Wen L; Javed MA; Criddle DN; Berry N; O'Neill PM; Lian LY; Sutton R
J Med Chem; 2016 Mar; 59(6):2596-611. PubMed ID: 26950392
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening.
Elkamhawy A; Park JE; Hassan AHE; Pae AN; Lee J; Park BG; Paik S; Do J; Park JH; Park KD; Moon B; Park WK; Cho H; Jeong DY; Roh EJ
Eur J Pharm Sci; 2017 Jun; 104():366-381. PubMed ID: 28435076
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of oxime derivatives as modulators for amyloid beta-induced mitochondrial dysfunction.
Kim YS; Jung SH; Park BG; Ko MK; Jang HS; Choi K; Baik JH; Lee J; Lee JK; Pae AN; Cho YS; Min SJ
Eur J Med Chem; 2013 Apr; 62():71-83. PubMed ID: 23353734
[TBL] [Abstract][Full Text] [Related]
12. Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta.
Du H; Yan SS
Biochim Biophys Acta; 2010 Jan; 1802(1):198-204. PubMed ID: 19616093
[TBL] [Abstract][Full Text] [Related]
13. Protective effects of astragaloside IV against amyloid beta1-42 neurotoxicity by inhibiting the mitochondrial permeability transition pore opening.
Sun Q; Jia N; Wang W; Jin H; Xu J; Hu H
PLoS One; 2014; 9(6):e98866. PubMed ID: 24905226
[TBL] [Abstract][Full Text] [Related]
14. Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.
Kim DI; Lee KH; Gabr AA; Choi GE; Kim JS; Ko SH; Han HJ
Biochim Biophys Acta; 2016 Nov; 1863(11):2820-2834. PubMed ID: 27599716
[TBL] [Abstract][Full Text] [Related]
15. Mitochondrial permeability transition pore in inflammatory apoptosis of human conjunctival epithelial cells and T cells: effect of cyclosporin A.
Gao J; Sana R; Calder V; Calonge M; Lee W; Wheeler LA; Stern ME
Invest Ophthalmol Vis Sci; 2013 Jul; 54(7):4717-33. PubMed ID: 23778874
[TBL] [Abstract][Full Text] [Related]
16. Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.
Kim T; Yang HY; Park BG; Jung SY; Park JH; Park KD; Min SJ; Tae J; Yang H; Cho S; Cho SJ; Song H; Mook-Jung I; Lee J; Pae AN
Eur J Med Chem; 2017 Jan; 125():1172-1192. PubMed ID: 27855359
[TBL] [Abstract][Full Text] [Related]
17. Effect of β-amyloid (25-35) on mitochondrial function and expression of mitochondrial permeability transition pore proteins in rat hippocampal neurons.
Ren R; Zhang Y; Li B; Wu Y; Li B
J Cell Biochem; 2011 May; 112(5):1450-7. PubMed ID: 21321998
[TBL] [Abstract][Full Text] [Related]
18. Cyclosporin A protects against Lead neurotoxicity through inhibiting mitochondrial permeability transition pore opening in nerve cells.
Ye F; Li X; Li F; Li J; Chang W; Yuan J; Chen J
Neurotoxicology; 2016 Dec; 57():203-213. PubMed ID: 27725305
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of mitochondrial permeability transition pore opening is involved in the protective effects of mortalin overexpression against beta-amyloid-induced apoptosis in SH-SY5Y cells.
Qu M; Zhou Z; Chen C; Li M; Pei L; Yang J; Wang Y; Li L; Liu C; Zhang G; Yu Z; Wang D
Neurosci Res; 2012 Jan; 72(1):94-102. PubMed ID: 22001761
[TBL] [Abstract][Full Text] [Related]
20. In silico-designed novel non-peptidic ABAD L
Viswanath ANI; Kim T; Jung SY; Lim SM; Pae AN
Chem Biol Drug Des; 2017 Dec; 90(6):1041-1055. PubMed ID: 28660722
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]