These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

777 related articles for article (PubMed ID: 28152480)

  • 1. Securinine enhances SMN2 exon 7 inclusion in spinal muscular atrophy cells.
    Chen YC; Chang JG; Liu TY; Jong YJ; Cheng WL; Yuo CY
    Biomed Pharmacother; 2017 Apr; 88():708-714. PubMed ID: 28152480
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High expression level of Tra2-β1 is responsible for increased SMN2 exon 7 inclusion in the testis of SMA mice.
    Chen YC; Chang JG; Jong YJ; Liu TY; Yuo CY
    PLoS One; 2015; 10(3):e0120721. PubMed ID: 25781985
    [TBL] [Abstract][Full Text] [Related]  

  • 3. hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1.
    Hofmann Y; Wirth B
    Hum Mol Genet; 2002 Aug; 11(17):2037-49. PubMed ID: 12165565
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting SR proteins improves SMN expression in spinal muscular atrophy cells.
    Wee CD; Havens MA; Jodelka FM; Hastings ML
    PLoS One; 2014; 9(12):e115205. PubMed ID: 25506695
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.
    Yuo CY; Lin HH; Chang YS; Yang WK; Chang JG
    Ann Neurol; 2008 Jan; 63(1):26-34. PubMed ID: 17924536
    [TBL] [Abstract][Full Text] [Related]  

  • 6. hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7.
    Cho S; Moon H; Loh TJ; Oh HK; Cho S; Choy HE; Song WK; Chun JS; Zheng X; Shen H
    Biochim Biophys Acta; 2014; 1839(4):306-15. PubMed ID: 24533984
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2).
    Hofmann Y; Lorson CL; Stamm S; Androphy EJ; Wirth B
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9618-23. PubMed ID: 10931943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combination of SMN trans-splicing and a neurotrophic factor increases the life span and body mass in a severe model of spinal muscular atrophy.
    Shababi M; Glascock J; Lorson CL
    Hum Gene Ther; 2011 Feb; 22(2):135-44. PubMed ID: 20804424
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA.
    Dominguez CE; Cunningham D; Venkataramany AS; Chandler DS
    Hum Genet; 2022 Feb; 141(2):239-256. PubMed ID: 35088120
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An in vivo reporter system for measuring increased inclusion of exon 7 in SMN2 mRNA: potential therapy of SMA.
    Zhang ML; Lorson CL; Androphy EJ; Zhou J
    Gene Ther; 2001 Oct; 8(20):1532-8. PubMed ID: 11704813
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Improvement of spinal muscular atrophy via correction of the SMN2 splicing defect by Brucea javanica (L.) Merr. extract and Bruceine D.
    Baek J; Jeong H; Ham Y; Jo YH; Choi M; Kang M; Son B; Choi S; Ryu HW; Kim J; Shen H; Sydara K; Lee SW; Kim SY; Han SB; Oh SR; Cho S
    Phytomedicine; 2019 Dec; 65():153089. PubMed ID: 31563042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Is RNA manipulation a viable therapy for spinal muscular atrophy?
    Horne C; Young PJ
    J Neurol Sci; 2009 Dec; 287(1-2):27-31. PubMed ID: 19758605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy.
    Thurmond J; Butchbach ME; Palomo M; Pease B; Rao M; Bedell L; Keyvan M; Pai G; Mishra R; Haraldsson M; Andresson T; Bragason G; Thosteinsdottir M; Bjornsson JM; Coovert DD; Burghes AH; Gurney ME; Singh J
    J Med Chem; 2008 Feb; 51(3):449-69. PubMed ID: 18205293
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atrophy cells.
    Pagliarini V; Guerra M; Di Rosa V; Compagnucci C; Sette C
    J Neurochem; 2020 Apr; 153(2):264-275. PubMed ID: 31811660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model.
    Bebee TW; Dominguez CE; Samadzadeh-Tarighat S; Akehurst KL; Chandler DS
    Hum Mol Genet; 2012 Oct; 21(19):4301-13. PubMed ID: 22763238
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of Inhibitors of SLC9A-Type Sodium-Proton Exchangers on
    Kanda S; Moulton E; Butchbach MER
    Mol Pharmacol; 2022 Aug; 102(2):92-105. PubMed ID: 35667685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.
    Cartegni L; Hastings ML; Calarco JA; de Stanchina E; Krainer AR
    Am J Hum Genet; 2006 Jan; 78(1):63-77. PubMed ID: 16385450
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy.
    Cobb MS; Rose FF; Rindt H; Glascock JJ; Shababi M; Miller MR; Osman EY; Yen PF; Garcia ML; Martin BR; Wetz MJ; Mazzasette C; Feng Z; Ko CP; Lorson CL
    Hum Mol Genet; 2013 May; 22(9):1843-55. PubMed ID: 23390132
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.
    Pedrotti S; Bielli P; Paronetto MP; Ciccosanti F; Fimia GM; Stamm S; Manley JL; Sette C
    EMBO J; 2010 Apr; 29(7):1235-47. PubMed ID: 20186123
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophy.
    Zhao X; Feng Z; Ling KK; Mollin A; Sheedy J; Yeh S; Petruska J; Narasimhan J; Dakka A; Welch EM; Karp G; Chen KS; Metzger F; Ratni H; Lotti F; Tisdale S; Naryshkin NA; Pellizzoni L; Paushkin S; Ko CP; Weetall M
    Hum Mol Genet; 2016 May; 25(10):1885-1899. PubMed ID: 26931466
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.