BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 28153791)

  • 1. HDAC6 deacetylates p53 at lysines 381/382 and differentially coordinates p53-induced apoptosis.
    Ryu HW; Shin DH; Lee DH; Choi J; Han G; Lee KY; Kwon SH
    Cancer Lett; 2017 Apr; 391():162-171. PubMed ID: 28153791
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis.
    Li D; Marchenko ND; Moll UM
    Cell Death Differ; 2011 Dec; 18(12):1904-13. PubMed ID: 21637290
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Drugging the HDAC6-HSP90 interplay in malignant cells.
    Krämer OH; Mahboobi S; Sellmer A
    Trends Pharmacol Sci; 2014 Oct; 35(10):501-9. PubMed ID: 25234862
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A potent hydroxamic acid-based, small-molecule inhibitor A452 preferentially inhibits HDAC6 activity and induces cytotoxicity toward cancer cells irrespective of p53 status.
    Ryu HW; Shin DH; Lee DH; Won HR; Kwon SH
    Carcinogenesis; 2018 Jan; 39(1):72-83. PubMed ID: 29106445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.
    Rao R; Fiskus W; Yang Y; Lee P; Joshi R; Fernandez P; Mandawat A; Atadja P; Bradner JE; Bhalla K
    Blood; 2008 Sep; 112(5):1886-93. PubMed ID: 18591380
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.
    Bali P; Pranpat M; Bradner J; Balasis M; Fiskus W; Guo F; Rocha K; Kumaraswamy S; Boyapalle S; Atadja P; Seto E; Bhalla K
    J Biol Chem; 2005 Jul; 280(29):26729-34. PubMed ID: 15937340
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
    Kovacs JJ; Murphy PJ; Gaillard S; Zhao X; Wu JT; Nicchitta CV; Yoshida M; Toft DO; Pratt WB; Yao TP
    Mol Cell; 2005 May; 18(5):601-7. PubMed ID: 15916966
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancement of stress resilience through histone deacetylase 6-mediated regulation of glucocorticoid receptor chaperone dynamics.
    Jochems J; Teegarden SL; Chen Y; Boulden J; Challis C; Ben-Dor GA; Kim SF; Berton O
    Biol Psychiatry; 2015 Feb; 77(4):345-55. PubMed ID: 25442004
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer.
    Seidel C; Schnekenburger M; Mazumder A; Teiten MH; Kirsch G; Dicato M; Diederich M
    Biochem Pharmacol; 2016 Jan; 99():31-52. PubMed ID: 26549368
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aceroside VIII is a new natural selective HDAC6 inhibitor that synergistically enhances the anticancer activity of HDAC inhibitor in HT29 cells.
    Ryu HW; Lee DH; Shin DH; Kim SH; Kwon SH
    Planta Med; 2015 Feb; 81(3):222-7. PubMed ID: 25590368
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting HSP90-HDAC6 Regulating Network Implicates Precision Treatment of Breast Cancer.
    Yu S; Cai X; Wu C; Liu Y; Zhang J; Gong X; Wang X; Wu X; Zhu T; Mo L; Gu J; Yu Z; Chen J; Thiery JP; Chai R; Chen L
    Int J Biol Sci; 2017; 13(4):505-517. PubMed ID: 28529458
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A452, an HDAC6-selective inhibitor, synergistically enhances the anticancer activity of chemotherapeutic agents in colorectal cancer cells.
    Won HR; Ryu HW; Shin DH; Yeon SK; Lee DH; Kwon SH
    Mol Carcinog; 2018 Oct; 57(10):1383-1395. PubMed ID: 29917295
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ARID1A-mutated ovarian cancers depend on HDAC6 activity.
    Bitler BG; Wu S; Park PH; Hai Y; Aird KM; Wang Y; Zhai Y; Kossenkov AV; Vara-Ailor A; Rauscher FJ; Zou W; Speicher DW; Huntsman DG; Conejo-Garcia JR; Cho KR; Christianson DW; Zhang R
    Nat Cell Biol; 2017 Aug; 19(8):962-973. PubMed ID: 28737768
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carbamazepine promotes Her-2 protein degradation in breast cancer cells by modulating HDAC6 activity and acetylation of Hsp90.
    Meng Q; Chen X; Sun L; Zhao C; Sui G; Cai L
    Mol Cell Biochem; 2011 Feb; 348(1-2):165-71. PubMed ID: 21082217
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arsenic trioxide exerts antimyeloma effects by inhibiting activity in the cytoplasmic substrates of histone deacetylase 6.
    Qu X; Du J; Zhang C; Fu W; Xi H; Zou J; Hou J
    PLoS One; 2012; 7(2):e32215. PubMed ID: 22384180
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
    Yang Y; Rao R; Shen J; Tang Y; Fiskus W; Nechtman J; Atadja P; Bhalla K
    Cancer Res; 2008 Jun; 68(12):4833-42. PubMed ID: 18559531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis.
    Lu CY; Chang YC; Hua CH; Chuang C; Huang SH; Kung SH; Hour MJ; Lin CW
    Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28468311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation.
    Park SY; Phorl S; Jung S; Sovannarith K; Lee SI; Noh S; Han M; Naskar R; Kim JY; Choi YJ; Lee JY
    Biochem Biophys Res Commun; 2017 Dec; 494(1-2):51-56. PubMed ID: 29054408
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.
    Joshi AD; Barabutis N; Birmpas C; Dimitropoulou C; Thangjam G; Cherian-Shaw M; Dennison J; Catravas JD
    Am J Physiol Lung Cell Mol Physiol; 2015 Dec; 309(12):L1410-9. PubMed ID: 26498249
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Posttranslational modification and beyond: interplay between histone deacetylase 6 and heat-shock protein 90.
    Liu P; Xiao J; Wang Y; Song X; Huang L; Ren Z; Kitazato K; Wang Y
    Mol Med; 2021 Sep; 27(1):110. PubMed ID: 34530730
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.