These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. Liu CY; Zha ZY; Zhou X; Zhang H; Huang W; Zhao D; Li T; Chan SW; Lim CJ; Hong W; Zhao S; Xiong Y; Lei QY; Guan KL J Biol Chem; 2010 Nov; 285(48):37159-69. PubMed ID: 20858893 [TBL] [Abstract][Full Text] [Related]
6. TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells. Finch-Edmondson ML; Strauss RP; Passman AM; Sudol M; Yeoh GC; Callus BA J Biol Chem; 2015 Nov; 290(46):27928-38. PubMed ID: 26432639 [TBL] [Abstract][Full Text] [Related]
7. Actin like-6A promotes glioma progression through stabilization of transcriptional regulators YAP/TAZ. Ji J; Xu R; Zhang X; Han M; Xu Y; Wei Y; Ding K; Wang S; Bin Huang ; Chen A; Di Zhang ; Jiang Z; Xu S; Zhang Q; Li W; Ni S; Wang J; Li X Cell Death Dis; 2018 May; 9(5):517. PubMed ID: 29725063 [TBL] [Abstract][Full Text] [Related]
8. Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP. Morelli M; Dennis AF; Patton JT mBio; 2015 Jan; 6(1):. PubMed ID: 25626907 [TBL] [Abstract][Full Text] [Related]
9. The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition. Huang W; Lv X; Liu C; Zha Z; Zhang H; Jiang Y; Xiong Y; Lei QY; Guan KL J Biol Chem; 2012 Jul; 287(31):26245-53. PubMed ID: 22692215 [TBL] [Abstract][Full Text] [Related]
10. Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation. Pham AM; Kwun HJ mBio; 2024 Aug; 15(8):e0111724. PubMed ID: 38940554 [TBL] [Abstract][Full Text] [Related]
11. PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein. Kedan A; Verma N; Saroha A; Shreberk-Shaked M; Müller AK; Nair NU; Lev S Cell Death Dis; 2018 Sep; 9(10):985. PubMed ID: 30250159 [TBL] [Abstract][Full Text] [Related]
12. TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells. Diamantopoulou Z; White G; Fadlullah MZH; Dreger M; Pickering K; Maltas J; Ashton G; MacLeod R; Baillie GS; Kouskoff V; Lacaud G; Murray GI; Sansom OJ; Hurlstone AFL; Malliri A Cancer Cell; 2017 May; 31(5):621-634.e6. PubMed ID: 28416184 [TBL] [Abstract][Full Text] [Related]
13. The novel YAP target gene, SGK1, upregulates TAZ activity by blocking GSK3β-mediated TAZ destabilization. Yoo G; Kim T; Chung C; Hwang DS; Lim DS Biochem Biophys Res Commun; 2017 Aug; 490(3):650-656. PubMed ID: 28634071 [TBL] [Abstract][Full Text] [Related]
14. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Zhao B; Li L; Tumaneng K; Wang CY; Guan KL Genes Dev; 2010 Jan; 24(1):72-85. PubMed ID: 20048001 [TBL] [Abstract][Full Text] [Related]
15. The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1. Janse van Rensburg HJ; Azad T; Ling M; Hao Y; Snetsinger B; Khanal P; Minassian LM; Graham CH; Rauh MJ; Yang X Cancer Res; 2018 Mar; 78(6):1457-1470. PubMed ID: 29339539 [TBL] [Abstract][Full Text] [Related]
16. Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation. Lin KC; Moroishi T; Meng Z; Jeong HS; Plouffe SW; Sekido Y; Han J; Park HW; Guan KL Nat Cell Biol; 2017 Jul; 19(8):996-1002. PubMed ID: 28752853 [TBL] [Abstract][Full Text] [Related]
17. Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ. Noto A; De Vitis C; Pisanu ME; Roscilli G; Ricci G; Catizone A; Sorrentino G; Chianese G; Taglialatela-Scafati O; Trisciuoglio D; Del Bufalo D; Di Martile M; Di Napoli A; Ruco L; Costantini S; Jakopin Z; Budillon A; Melino G; Del Sal G; Ciliberto G; Mancini R Oncogene; 2017 Aug; 36(32):4573-4584. PubMed ID: 28368399 [TBL] [Abstract][Full Text] [Related]
18. OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ. Zhang Z; Du J; Wang S; Shao L; Jin K; Li F; Wei B; Ding W; Fu P; van Dam H; Wang A; Jin J; Ding C; Yang B; Zheng M; Feng XH; Guan KL; Zhang L Mol Cell; 2019 Jan; 73(1):7-21.e7. PubMed ID: 30472188 [TBL] [Abstract][Full Text] [Related]
19. Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. Liu F; Lagares D; Choi KM; Stopfer L; Marinković A; Vrbanac V; Probst CK; Hiemer SE; Sisson TH; Horowitz JC; Rosas IO; Fredenburgh LE; Feghali-Bostwick C; Varelas X; Tager AM; Tschumperlin DJ Am J Physiol Lung Cell Mol Physiol; 2015 Feb; 308(4):L344-57. PubMed ID: 25502501 [TBL] [Abstract][Full Text] [Related]
20. Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation. Zhang L; Zhou F; Li Y; Drabsch Y; Zhang J; van Dam H; ten Dijke P J Biol Chem; 2012 Aug; 287(36):30701-10. PubMed ID: 22730322 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]