These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 28154193)

  • 1. Dissecting the Molecular Pathway Involved in PLK2 Kinase-mediated α-Synuclein-selective Autophagic Degradation.
    Dahmene M; Bérard M; Oueslati A
    J Biol Chem; 2017 Mar; 292(9):3919-3928. PubMed ID: 28154193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain.
    Bergeron M; Motter R; Tanaka P; Fauss D; Babcock M; Chiou SS; Nelson S; San Pablo F; Anderson JP
    Neuroscience; 2014 Jan; 256():72-82. PubMed ID: 24128992
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo.
    Oueslati A; Schneider BL; Aebischer P; Lashuel HA
    Proc Natl Acad Sci U S A; 2013 Oct; 110(41):E3945-54. PubMed ID: 23983262
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization.
    Samuel F; Flavin WP; Iqbal S; Pacelli C; Sri Renganathan SD; Trudeau LE; Campbell EM; Fraser PE; Tandon A
    J Biol Chem; 2016 Feb; 291(9):4374-85. PubMed ID: 26719332
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polo-like kinase 2 inhibition reduces serine-129 phosphorylation of physiological nuclear alpha-synuclein but not of the aggregated alpha-synuclein.
    Elfarrash S; Jensen NM; Ferreira N; Schmidt SI; Gregersen E; Vestergaard MV; Nabavi S; Meyer M; Jensen PH
    PLoS One; 2021; 16(10):e0252635. PubMed ID: 34613964
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of synucleins by members of the Polo-like kinase family.
    Mbefo MK; Paleologou KE; Boucharaba A; Oueslati A; Schell H; Fournier M; Olschewski D; Yin G; Zweckstetter M; Masliah E; Kahle PJ; Hirling H; Lashuel HA
    J Biol Chem; 2010 Jan; 285(4):2807-22. PubMed ID: 19889641
    [TBL] [Abstract][Full Text] [Related]  

  • 7. E46K Mutant α-Synuclein Is Degraded by Both Proteasome and Macroautophagy Pathway.
    Yan JQ; Yuan YH; Chu SF; Li GH; Chen NH
    Molecules; 2018 Nov; 23(11):. PubMed ID: 30388770
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo.
    Mbefo MK; Fares MB; Paleologou K; Oueslati A; Yin G; Tenreiro S; Pinto M; Outeiro T; Zweckstetter M; Masliah E; Lashuel HA
    J Biol Chem; 2015 Apr; 290(15):9412-27. PubMed ID: 25657004
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation.
    Cai CZ; Zhou HF; Yuan NN; Wu MY; Lee SM; Ren JY; Su HX; Lu JJ; Chen XP; Li M; Tan JQ; Lu JH
    Phytomedicine; 2019 Aug; 61():152842. PubMed ID: 31048127
    [TBL] [Abstract][Full Text] [Related]  

  • 10. miR-101-3p Contributes to
    Zhang M; Liu W; Zhang Q; Hu H
    J Healthc Eng; 2021; 2021():6147434. PubMed ID: 34234930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development and characterization of polo-like kinase 2 loaded nanoparticles-A novel strategy for (serine-129) phosphorylation of alpha-synuclein.
    Rodríguez-Nogales C; Garbayo E; Martínez-Valbuena I; Sebastián V; Luquin MR; Blanco-Prieto MJ
    Int J Pharm; 2016 Nov; 514(1):142-149. PubMed ID: 27863657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.
    Mahul-Mellier AL; Fauvet B; Gysbers A; Dikiy I; Oueslati A; Georgeon S; Lamontanara AJ; Bisquertt A; Eliezer D; Masliah E; Halliday G; Hantschel O; Lashuel HA
    Hum Mol Genet; 2014 Jun; 23(11):2858-79. PubMed ID: 24412932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.
    Buck K; Landeck N; Ulusoy A; Majbour NK; El-Agnaf OM; Kirik D
    Neurobiol Dis; 2015 Jun; 78():100-14. PubMed ID: 25818009
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains.
    Chen M; Yang W; Li X; Li X; Wang P; Yue F; Yang H; Chan P; Yu S
    Oncotarget; 2016 Feb; 7(8):8466-80. PubMed ID: 27032368
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling.
    Hong CT; Chen KY; Wang W; Chiu JY; Wu D; Chao TY; Hu CJ; Chau KD; Bamodu OA
    Cells; 2020 Mar; 9(3):. PubMed ID: 32192190
    [No Abstract]   [Full Text] [Related]  

  • 16. Targeted degradation of ⍺-synuclein aggregates in Parkinson's disease using the AUTOTAC technology.
    Lee J; Sung KW; Bae EJ; Yoon D; Kim D; Lee JS; Park DH; Park DY; Mun SR; Kwon SC; Kim HY; Min JO; Lee SJ; Suh YH; Kwon YT
    Mol Neurodegener; 2023 Jun; 18(1):41. PubMed ID: 37355598
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-Synuclein phosphorylation as a therapeutic target in Parkinson's disease.
    Braithwaite SP; Stock JB; Mouradian MM
    Rev Neurosci; 2012 Mar; 23(2):191-8. PubMed ID: 22499677
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Iron-induced oxidative stress contributes to α-synuclein phosphorylation and up-regulation via polo-like kinase 2 and casein kinase 2.
    Wang R; Wang Y; Qu L; Chen B; Jiang H; Song N; Xie J
    Neurochem Int; 2019 May; 125():127-135. PubMed ID: 30797969
    [TBL] [Abstract][Full Text] [Related]  

  • 19. S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson's disease.
    Wu W; Sung CC; Yu P; Li J; Chung KKK
    PLoS One; 2020; 15(4):e0232019. PubMed ID: 32343709
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system.
    Inglis KJ; Chereau D; Brigham EF; Chiou SS; Schöbel S; Frigon NL; Yu M; Caccavello RJ; Nelson S; Motter R; Wright S; Chian D; Santiago P; Soriano F; Ramos C; Powell K; Goldstein JM; Babcock M; Yednock T; Bard F; Basi GS; Sham H; Chilcote TJ; McConlogue L; Griswold-Prenner I; Anderson JP
    J Biol Chem; 2009 Jan; 284(5):2598-2602. PubMed ID: 19004816
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.