BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 28158555)

  • 1. Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motif.
    Pauty J; Couturier AM; Rodrigue A; Caron MC; Coulombe Y; Dellaire G; Masson JY
    Nucleic Acids Res; 2017 Mar; 45(5):2644-2657. PubMed ID: 28158555
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
    Park JY; Singh TR; Nassar N; Zhang F; Freund M; Hanenberg H; Meetei AR; Andreassen PR
    Oncogene; 2014 Oct; 33(40):4803-12. PubMed ID: 24141787
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Missense PALB2 germline variant disrupts nuclear localization of PALB2 in a patient with breast cancer.
    Toh MR; Low CE; Chong ST; Chan SH; Ishak NDB; Courtney E; Kolinjivadi AM; Rodrigue A; Masson JY; Ngeow J
    Fam Cancer; 2020 Apr; 19(2):123-131. PubMed ID: 32048105
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients.
    Obermeier K; Sachsenweger J; Friedl TW; Pospiech H; Winqvist R; Wiesmüller L
    Oncogene; 2016 Jul; 35(29):3796-806. PubMed ID: 26640152
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PALB2 self-interaction controls homologous recombination.
    Buisson R; Masson JY
    Nucleic Acids Res; 2012 Nov; 40(20):10312-23. PubMed ID: 22941656
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Compromised BRCA1-PALB2 interaction is associated with breast cancer risk.
    Foo TK; Tischkowitz M; Simhadri S; Boshari T; Zayed N; Burke KA; Berman SH; Blecua P; Riaz N; Huo Y; Ding YC; Neuhausen SL; Weigelt B; Reis-Filho JS; Foulkes WD; Xia B
    Oncogene; 2017 Jul; 36(29):4161-4170. PubMed ID: 28319063
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
    Dray E; Etchin J; Wiese C; Saro D; Williams GJ; Hammel M; Yu X; Galkin VE; Liu D; Tsai MS; Sy SM; Schild D; Egelman E; Chen J; Sung P
    Nat Struct Mol Biol; 2010 Oct; 17(10):1255-9. PubMed ID: 20871616
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PALB2 regulates recombinational repair through chromatin association and oligomerization.
    Sy SM; Huen MS; Zhu Y; Chen J
    J Biol Chem; 2009 Jul; 284(27):18302-10. PubMed ID: 19423707
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function.
    Ahlskog JK; Larsen BD; Achanta K; Sørensen CS
    EMBO Rep; 2016 May; 17(5):671-81. PubMed ID: 27113759
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Two nuclear export signals of Cdc6 are differentially associated with CDK-mediated phosphorylation residues for cytoplasmic translocation.
    Hwang IS; Woo SU; Park JW; Lee SK; Yim H
    Biochim Biophys Acta; 2014 Feb; 1843(2):223-33. PubMed ID: 24216307
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PALB2: the hub of a network of tumor suppressors involved in DNA damage responses.
    Park JY; Zhang F; Andreassen PR
    Biochim Biophys Acta; 2014 Aug; 1846(1):263-75. PubMed ID: 24998779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for recruitment of BRCA2 by PALB2.
    Oliver AW; Swift S; Lord CJ; Ashworth A; Pearl LH
    EMBO Rep; 2009 Sep; 10(9):990-6. PubMed ID: 19609323
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
    Buisson R; Dion-Côté AM; Coulombe Y; Launay H; Cai H; Stasiak AZ; Stasiak A; Xia B; Masson JY
    Nat Struct Mol Biol; 2010 Oct; 17(10):1247-54. PubMed ID: 20871615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair.
    Bleuyard JY; Buisson R; Masson JY; Esashi F
    EMBO Rep; 2012 Feb; 13(2):135-41. PubMed ID: 22193777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PALB2 mutations in BRCA1/2-mutation negative breast and ovarian cancer patients from Poland.
    Kluska A; Balabas A; Piatkowska M; Czarny K; Paczkowska K; Nowakowska D; Mikula M; Ostrowski J
    BMC Med Genomics; 2017 Mar; 10(1):14. PubMed ID: 28279176
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An integrated in silico approach to analyze the involvement of single amino acid polymorphisms in FANCD1/BRCA2-PALB2 and FANCD1/BRCA2-RAD51 complex.
    Doss CG; Nagasundaram N
    Cell Biochem Biophys; 2014 Nov; 70(2):939-56. PubMed ID: 24817641
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A recurrent mutation in PALB2 in Finnish cancer families.
    Erkko H; Xia B; Nikkilä J; Schleutker J; Syrjäkoski K; Mannermaa A; Kallioniemi A; Pylkäs K; Karppinen SM; Rapakko K; Miron A; Sheng Q; Li G; Mattila H; Bell DW; Haber DA; Grip M; Reiman M; Jukkola-Vuorinen A; Mustonen A; Kere J; Aaltonen LA; Kosma VM; Kataja V; Soini Y; Drapkin RI; Livingston DM; Winqvist R
    Nature; 2007 Mar; 446(7133):316-9. PubMed ID: 17287723
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.
    Ferrer M; Rodríguez JA; Spierings EA; de Winter JP; Giaccone G; Kruyt FA
    Hum Mol Genet; 2005 May; 14(10):1271-81. PubMed ID: 15790592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A PALB2 mutation associated with high risk of breast cancer.
    Southey MC; Teo ZL; Dowty JG; Odefrey FA; Park DJ; Tischkowitz M; Sabbaghian N; Apicella C; Byrnes GB; Winship I; Baglietto L; Giles GG; Goldgar DE; Foulkes WD; Hopper JL;
    Breast Cancer Res; 2010; 12(6):R109. PubMed ID: 21182766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families.
    García MJ; Fernández V; Osorio A; Barroso A; Llort G; Lázaro C; Blanco I; Caldés T; de la Hoya M; Ramón Y Cajal T; Alonso C; Tejada MI; San Román C; Robles-Díaz L; Urioste M; Benítez J
    Breast Cancer Res Treat; 2009 Feb; 113(3):545-51. PubMed ID: 18302019
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.