BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 28161251)

  • 1. Carbonic anhydrases activation with 3-amino-1H-1,2,4-triazole-1-carboxamides: Discovery of subnanomolar isoform II activators.
    Le Duc Y; Licsandru E; Vullo D; Barboiu M; Supuran CT
    Bioorg Med Chem; 2017 Mar; 25(5):1681-1686. PubMed ID: 28161251
    [TBL] [Abstract][Full Text] [Related]  

  • 2. α-Carbonic anhydrases are strongly activated by spinaceamine derivatives.
    Akocak S; Lolak N; Bua S; Nocentini A; Karakoc G; Supuran CT
    Bioorg Med Chem; 2019 Mar; 27(5):800-804. PubMed ID: 30683554
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme.
    Temperini C; Scozzafava A; Vullo D; Supuran CT
    Chemistry; 2006 Sep; 12(27):7057-66. PubMed ID: 16807956
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A class of carbonic anhydrase I - selective activators.
    Licsandru E; Tanc M; Kocsis I; Barboiu M; Supuran CT
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):37-46. PubMed ID: 27798977
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Designing of novel carbonic anhydrase inhibitors and activators.
    Supuran CT; Vullo D; Manole G; Casini A; Scozzafava A
    Curr Med Chem Cardiovasc Hematol Agents; 2004 Jan; 2(1):49-68. PubMed ID: 15328829
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.
    Almajan GL; Innocenti A; Puccetti L; Manole G; Barbuceanu S; Saramet I; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2005 May; 15(9):2347-52. PubMed ID: 15837323
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carbonic anhydrase activation profile of indole-based derivatives.
    Barresi E; Ravichandran R; Germelli L; Angeli A; Baglini E; Salerno S; Marini AM; Costa B; Da Pozzo E; Martini C; Da Settimo F; Supuran C; Cosconati S; Taliani S
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):1783-1797. PubMed ID: 34340630
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carbonic anhydrase activators: synthesis of high affinity isozymes I, II and IV activators, derivatives of 4-(arylsulfonylureido-amino acyl)ethyl-1H-imidazole.
    Supuran CT; Scozzafava A
    J Enzyme Inhib; 2000; 15(5):471-86. PubMed ID: 11030087
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design.
    Temperini C; Scozzafava A; Vullo D; Supuran CT
    J Med Chem; 2006 May; 49(10):3019-27. PubMed ID: 16686544
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII.
    Grandane A; Tanc M; Zalubovskis R; Supuran CT
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1256-60. PubMed ID: 24518190
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.
    Parkkila S; Vullo D; Puccetti L; Parkkila AK; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2006 Aug; 16(15):3955-9. PubMed ID: 16730978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. (Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators.
    Rami M; Winum JY; Supuran CT; Melnyk P; Yous S
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):224-229. PubMed ID: 30734616
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mono- and di-halogenated histamine, histidine and carnosine derivatives are potent carbonic anhydrase I, II, VII, XII and XIV activators.
    Saada MC; Vullo D; Montero JL; Scozzafava A; Supuran CT; Winum JY
    Bioorg Med Chem; 2014 Sep; 22(17):4752-8. PubMed ID: 25082511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators.
    Temperini C; Scozzafava A; Puccetti L; Supuran CT
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5136-41. PubMed ID: 16214338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines.
    Vullo D; Innocenti A; Nishimori I; Scozzafava A; Kaila K; Supuran CT
    Bioorg Med Chem Lett; 2007 Aug; 17(15):4107-12. PubMed ID: 17540561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Carbonic anhydrase activators - part 21. Novel activators of isozymes I, II and IV incorporating carboxamido and ureido histamine moieties.
    Scozzafava A; Supuran CT
    Eur J Med Chem; 2000 Jan; 35(1):31-9. PubMed ID: 10733601
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Carbonic anhydrase activators: gold nanoparticles coated with derivatized histamine, histidine, and carnosine show enhanced activatory effects on several mammalian isoforms.
    Saada MC; Montero JL; Vullo D; Scozzafava A; Winum JY; Supuran CT
    J Med Chem; 2011 Mar; 54(5):1170-7. PubMed ID: 21291238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carbonic anhydrase activators: synthesis of high affinity isozymes I, II and IV activators, derivatives of 4-(4-tosylureido-amino acyl)ethyl-1H-imidazole (histamine derivatives).
    Scozzafava A; Iorga B; Supuran CT
    J Enzyme Inhib; 2000; 15(2):139-61. PubMed ID: 10938540
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amine- and Amino Acid-Based Compounds as Carbonic Anhydrase Activators.
    Angeli A; Berrino E; Carradori S; Supuran CT; Cirri M; Carta F; Costantino G
    Molecules; 2021 Dec; 26(23):. PubMed ID: 34885917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Benzenesulfonamide bearing 1,2,4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII.
    SitaRam ; Celik G; Khloya P; Vullo D; Supuran CT; Sharma PK
    Bioorg Med Chem; 2014 Mar; 22(6):1873-82. PubMed ID: 24560737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.