These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 28161411)

  • 1. Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008.
    Ruiz FX; Crespo I; Álvarez S; Porté S; Giménez-Dejoz J; Cousido-Siah A; Mitschler A; de Lera ÁR; Parés X; Podjarny A; Farrés J
    Chem Biol Interact; 2017 Oct; 276():174-181. PubMed ID: 28161411
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: role of Trp112 (Trp111).
    Zhang L; Zhang H; Zhao Y; Li Z; Chen S; Zhai J; Chen Y; Xie W; Wang Z; Li Q; Zheng X; Hu X
    FEBS Lett; 2013 Nov; 587(22):3681-6. PubMed ID: 24100137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.
    Ruiz FX; Cousido-Siah A; Mitschler A; Farrés J; Parés X; Podjarny A
    Chem Biol Interact; 2013 Feb; 202(1-3):178-85. PubMed ID: 23295227
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and structure-activity relationship of 2-phenyliminochromene derivatives as inhibitors for aldo-keto reductase (AKR) 1B10.
    Endo S; Hu D; Suyama M; Matsunaga T; Sugimoto K; Matsuya Y; El-Kabbani O; Kuwata K; Hara A; Kitade Y; Toyooka N
    Bioorg Med Chem; 2013 Nov; 21(21):6378-84. PubMed ID: 24071447
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors.
    Cousido-Siah A; Ruiz FX; Fanfrlík J; Giménez-Dejoz J; Mitschler A; Kamlar M; Veselý J; Ajani H; Parés X; Farrés J; Hobza P; Podjarny AD
    ACS Chem Biol; 2016 Oct; 11(10):2693-2705. PubMed ID: 27359042
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids.
    Beard RL; Chandraratna RA; Colon DF; Gillett SJ; Henry E; Marler DK; Song T; Denys L; Garst ME; Arefieg T
    J Med Chem; 1995 Jul; 38(15):2820-9. PubMed ID: 7636843
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity.
    Porté S; Xavier Ruiz F; Giménez J; Molist I; Alvarez S; Domínguez M; Alvarez R; de Lera AR; Parés X; Farrés J
    Chem Biol Interact; 2013 Feb; 202(1-3):186-94. PubMed ID: 23220004
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10.
    Soda M; Hu D; Endo S; Takemura M; Li J; Wada R; Ifuku S; Zhao HT; El-Kabbani O; Ohta S; Yamamura K; Toyooka N; Hara A; Matsunaga T
    Eur J Med Chem; 2012 Feb; 48():321-9. PubMed ID: 22236472
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of steroidal derivatives as selective inhibitors of AKR1B10.
    Zhang W; Wang L; Zhang L; Chen W; Chen X; Xie M; Yan G; Hu X; Xu J; Zhang J
    Steroids; 2014 Aug; 86():39-44. PubMed ID: 24793566
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design.
    Cousido-Siah A; Ruiz FX; Mitschler A; Porté S; de Lera ÁR; Martín MJ; Manzanaro S; de la Fuente JA; Terwesten F; Betz M; Klebe G; Farrés J; Parés X; Podjarny A
    Acta Crystallogr D Biol Crystallogr; 2014 Mar; 70(Pt 3):889-903. PubMed ID: 24598757
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for the inhibition of AKR1B10 by caffeic acid phenethyl ester (CAPE).
    Zhang L; Zhang H; Zheng X; Zhao Y; Chen S; Chen Y; Zhang R; Li Q; Hu X
    ChemMedChem; 2014 Apr; 9(4):706-9. PubMed ID: 24436249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10.
    Ruiz FX; Cousido-Siah A; Porté S; Domínguez M; Crespo I; Rechlin C; Mitschler A; de Lera ÁR; Martín MJ; de la Fuente JÁ; Klebe G; Parés X; Farrés J; Podjarny A
    ChemMedChem; 2015 Dec; 10(12):1989-2003. PubMed ID: 26549844
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Perspective on the Structural Basis for Human Aldo-Keto Reductase 1B10 Inhibition.
    Ruiz FX; Parés X; Farrés J
    Metabolites; 2021 Dec; 11(12):. PubMed ID: 34940623
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective inhibition of the tumor marker AKR1B10 by antiinflammatory N-phenylanthranilic acids and glycyrrhetic acid.
    Endo S; Matsunaga T; Soda M; Tajima K; Zhao HT; El-Kabbani O; Hara A
    Biol Pharm Bull; 2010; 33(5):886-90. PubMed ID: 20460771
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Engineering aldo-keto reductase 1B10 to mimic the distinct 1B15 topology and specificity towards inhibitors and substrates, including retinoids and steroids.
    Giménez-Dejoz J; Weber S; Fernández-Pardo Á; Möller G; Adamski J; Porté S; Parés X; Farrés J
    Chem Biol Interact; 2019 Jul; 307():186-194. PubMed ID: 31028727
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
    Klaholz BP; Mitschler A; Moras D
    J Mol Biol; 2000 Sep; 302(1):155-70. PubMed ID: 10964567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids.
    Boehm MF; Zhang L; Badea BA; White SK; Mais DE; Berger E; Suto CM; Goldman ME; Heyman RA
    J Med Chem; 1994 Sep; 37(18):2930-41. PubMed ID: 8071941
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pattern of retinoid-induced teratogenic effects: possible relationship with relative selectivity for nuclear retinoid receptors RAR alpha, RAR beta, and RAR gamma.
    Elmazar MM; Reichert U; Shroot B; Nau H
    Teratology; 1996 Mar; 53(3):158-67. PubMed ID: 8761883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of aldo-keto reductase family 1 member B10 by unsaturated fatty acids.
    Hara A; Endo S; Matsunaga T; Soda M; El-Kabbani O; Yashiro K
    Arch Biochem Biophys; 2016 Nov; 609():69-76. PubMed ID: 27665999
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition.
    Pignatello MA; Kauffman FC; Levin AA
    Toxicol Appl Pharmacol; 1997 Feb; 142(2):319-27. PubMed ID: 9070355
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.