These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 28163135)

  • 21. Mass spectral characterization of dichloroacetic acid-modified human glutathione transferase zeta.
    Anderson WB; Liebler DC; Board PG; Anders MW
    Chem Res Toxicol; 2002 Nov; 15(11):1387-97. PubMed ID: 12437329
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1.
    Li W; James MO; McKenzie SC; Calcutt NA; Liu C; Stacpoole PW
    J Pharmacol Exp Ther; 2011 Jan; 336(1):87-94. PubMed ID: 20884751
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Regulation of dichloroacetate biotransformation in rat liver and extrahepatic tissues by GSTZ1 expression and chloride concentration.
    Jahn SC; Smeltz MG; Hu Z; Rowland-Faux L; Zhong G; Lorenzo RJ; Cisneros KV; Stacpoole PW; James MO
    Biochem Pharmacol; 2018 Jun; 152():236-243. PubMed ID: 29626439
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid.
    Tong Z; Board PG; Anders MW
    Biochem J; 1998 Apr; 331 ( Pt 2)(Pt 2):371-4. PubMed ID: 9531472
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Human glutathione transferase zeta.
    Board PG; Anders MW
    Methods Enzymol; 2005; 401():61-77. PubMed ID: 16399379
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Age-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity.
    Shroads AL; Guo X; Dixit V; Liu HP; James MO; Stacpoole PW
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1163-71. PubMed ID: 18096758
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate.
    Li W; Gu Y; James MO; Hines RN; Simpson P; Langaee T; Stacpoole PW
    Drug Metab Dispos; 2012 Feb; 40(2):232-9. PubMed ID: 22028318
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues.
    Lantum HB; Baggs RB; Krenitsky DM; Board PG; Anders MW
    Drug Metab Dispos; 2002 Jun; 30(6):616-25. PubMed ID: 12019185
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.
    Guo X; Dixit V; Liu H; Shroads AL; Henderson GN; James MO; Stacpoole PW
    Drug Metab Dispos; 2006 Jan; 34(1):36-42. PubMed ID: 16199472
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans.
    Shroads AL; Coats BS; Langaee T; Shuster JJ; Stacpoole PW
    Drug Metab Pers Ther; 2015 Mar; 30(1):49-55. PubMed ID: 25283137
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Glutathione transferase zeta-catalyzed bioactivation of dichloroacetic acid: reaction of glyoxylate with amino acid nucleophiles.
    Anderson WB; Board PG; Anders MW
    Chem Res Toxicol; 2004 May; 17(5):650-62. PubMed ID: 15144222
    [TBL] [Abstract][Full Text] [Related]  

  • 32. GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate.
    Jahn SC; Solayman MH; Lorenzo RJ; Langaee T; Stacpoole PW; James MO
    Biochim Biophys Acta; 2016 Jun; 1860(6):1202-10. PubMed ID: 26850694
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Clinical physiology and pharmacology of GSTZ1/MAAI.
    Stacpoole PW
    Biochem Pharmacol; 2023 Nov; 217():115818. PubMed ID: 37742772
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Dichloroacetate (DCA) dosimetry: interpreting DCA-induced liver cancer dose response and the potential for DCA to contribute to trichloroethylene-induced liver cancer.
    Barton HA; Bull R; Schultz I; Andersen ME
    Toxicol Lett; 1999 May; 106(1):9-21. PubMed ID: 10378446
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Dichloroacetic acid up-regulates hepatic glutathione synthesis via the induction of glutamate-cysteine ligase.
    Theodoratos A; Blackburn AC; Cappello J; Tummala P; Dahlstrom JE; Board PG
    Biochem Pharmacol; 2012 Feb; 83(3):427-33. PubMed ID: 22127296
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dichloroacetic acid pretreatment of male and female rats increases chloroform-induced hepatotoxicity.
    Yang HM; Davis ME
    Toxicology; 1997 Dec; 124(1):63-72. PubMed ID: 9392456
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate.
    Shroads AL; Langaee T; Coats BS; Kurtz TL; Bullock JR; Weithorn D; Gong Y; Wagner DA; Ostrov DA; Johnson JA; Stacpoole PW
    J Clin Pharmacol; 2012 Jun; 52(6):837-49. PubMed ID: 21642471
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dichloroacetic acid pretreatment of male and female rats increases chloroform metabolism in vitro.
    Yang HM; Davis ME
    Toxicology; 1997 Dec; 124(1):53-62. PubMed ID: 9392455
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids.
    Tong Z; Board PG; Anders MW
    Chem Res Toxicol; 1998 Nov; 11(11):1332-8. PubMed ID: 9815194
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dichloroacetate: population pharmacokinetics with a pharmacodynamic sequential link model.
    Williams PJ; Lane JR; Turkel CC; Capparelli EV; Dziewanowska Z; Fox AW
    J Clin Pharmacol; 2001 Mar; 41(3):259-67. PubMed ID: 11269566
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.