BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 28163339)

  • 1. Synthesis and antiviral evaluation of 2',2',3',3'-tetrafluoro nucleoside analogs.
    Sari O; Bassit L; Gavegnano C; McBrayer TR; McCormick L; Cox B; Coats SJ; Amblard F; Schinazi RF
    Tetrahedron Lett; 2017 Feb; 58(7):642-644. PubMed ID: 28163339
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efficient synthesis of nucleoside aryloxy phosphoramidate prodrugs utilizing benzyloxycarbonyl protection.
    Cho JH; Amblard F; Coats SJ; Schinazi RF
    Tetrahedron; 2011 Jul; 67(30):5487-5493. PubMed ID: 22993455
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5'-triphosphates.
    Shi J; Zhou L; Zhang H; McBrayer TR; Detorio MA; Johns M; Bassit L; Powdrill MH; Whitaker T; Coats SJ; Götte M; Schinazi RF
    Bioorg Med Chem Lett; 2011 Dec; 21(23):7094-8. PubMed ID: 22014549
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
    McGuigan C; Bourdin C; Derudas M; Hamon N; Hinsinger K; Kandil S; Madela K; Meneghesso S; Pertusati F; Serpi M; Slusarczyk M; Chamberlain S; Kolykhalov A; Vernachio J; Vanpouille C; Introini A; Margolis L; Balzarini J
    Eur J Med Chem; 2013; 70():326-40. PubMed ID: 24177359
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.
    Rondla R; Coats SJ; McBrayer TR; Grier J; Johns M; Tharnish PM; Whitaker T; Zhou L; Schinazi RF
    Antivir Chem Chemother; 2009 Oct; 20(2):99-106. PubMed ID: 19843980
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of 4'-Substituted Carbocyclic Uracil Derivatives and Their Monophosphate Prodrugs as Potential Antiviral Agents.
    Biteau NG; Amichai SA; Azadi N; De R; Downs-Bowen J; Lecher JC; MacBrayer T; Schinazi RF; Amblard F
    Viruses; 2023 Feb; 15(2):. PubMed ID: 36851758
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of Phosphoramidate ProTide Technology for the Synthesis of 5'-mRNA Cap Analogs Modified on the Exocyclic Amine Group.
    Siekierska I; Lukaszewicz M; Worch R; Jankowska-Anyszka M; Piecyk K
    ChemMedChem; 2023 Feb; 18(4):e202200490. PubMed ID: 36658701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and anti-HCV activity of a series of β-d-2'-deoxy-2'-dibromo nucleosides and their corresponding phosphoramidate prodrugs.
    Chen Z; Cox BD; Garnier-Amblard EC; McBrayer TR; Coats SJ; Schinazi RF; Amblard F
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5296-5299. PubMed ID: 29066308
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tissue-Specific Proteomics Analysis of Anti-COVID-19 Nucleoside and Nucleotide Prodrug-Activating Enzymes Provides Insights into the Optimization of Prodrug Design and Pharmacotherapy Strategy.
    Li J; Liu S; Shi J; Wang X; Xue Y; Zhu HJ
    ACS Pharmacol Transl Sci; 2021 Apr; 4(2):870-887. PubMed ID: 33855276
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Adenosine Dioxolane Nucleoside Phosphoramidates as Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses.
    Bondada L; Detorio M; Bassit L; Tao S; Montero CM; Singletary TM; Zhang H; Zhou L; Cho JH; Coats SJ; Schinazi RF
    ACS Med Chem Lett; 2013 Aug; 4(8):747-751. PubMed ID: 24015326
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphoramidate Prodrugs Continue to Deliver, The Journey of Remdesivir (GS-5734) from RSV to SARS-CoV-2.
    Mackman RL
    ACS Med Chem Lett; 2022 Mar; 13(3):338-347. PubMed ID: 35291757
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
    Saboulard D; Naesens L; Cahard D; Salgado A; Pathirana R; Velazquez S; McGuigan C; De Clercq E; Balzarini J
    Mol Pharmacol; 1999 Oct; 56(4):693-704. PubMed ID: 10496951
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of Nucleosides and Nucleotides Prodrugs.
    De Schutter C; Ehteshami M; Hammond ET; Amblard F; Schinazi RF
    Curr Pharm Des; 2017 Oct; ():. PubMed ID: 29022511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs.
    Pileggi E; Serpi M; Andrei G; Schols D; Snoeck R; Pertusati F
    Bioorg Med Chem; 2018 Jul; 26(12):3596-3609. PubMed ID: 29880251
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of phosphonate derivatives of 2'-deoxy-2'-fluorotetradialdose d-nucleosides and tetradialdose d-nucleosides.
    Lášek T; Dobiáš J; Buděšínský M; Kozák J; Lapuníková B; Rosenberg I; Birkuš G; Páv O
    Tetrahedron; 2021 Jun; 89():132159. PubMed ID: 33879930
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of 6-Aza-2-Hydroxyimino-5-Methylpyrimidine Nucleosides for Antiviral Evaluation.
    Abou-Elkhair RAI; Du J; Wasfy AA; Khaill NA; Maaroof HM; Hassan MH; Ahmed AS; Hassan AEA; Sheng J
    Curr Protoc; 2021 Dec; 1(12):e329. PubMed ID: 34878712
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In silico design of a novel nucleotide antiviral agent by free energy perturbation.
    Patel D; Cox BD; Kasthuri M; Mengshetti S; Bassit L; Verma K; Ollinger-Russell O; Amblard F; Schinazi RF
    Chem Biol Drug Des; 2022 Jun; 99(6):801-815. PubMed ID: 35313085
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs.
    McMillan RE; Lo MK; Zhang XQ; Beadle JR; Valiaeva N; Garretson AF; Clark AE; Freshman JE; Murphy J; Montgomery JM; Spiropoulou CF; Schooley RT; Hostetler KY; Carlin AF
    Antiviral Res; 2023 Nov; 219():105718. PubMed ID: 37758067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hydrolytic reactions of thymidine 5'-o-phenyl-N-alkylphosphoramidates, models of nucleoside 5'-monophosphate prodrugs.
    Ora M; Ojanperä J; Lönnberg H
    Chemistry; 2007; 13(30):8591-9. PubMed ID: 17654626
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses.
    Milisavljevic N; Konkolová E; Kozák J; Hodek J; Veselovská L; Sýkorová V; Čížek K; Pohl R; Eyer L; Svoboda P; Růžek D; Weber J; Nencka R; Bouřa E; Hocek M
    ACS Infect Dis; 2021 Feb; 7(2):471-478. PubMed ID: 33395259
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.