BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 28167297)

  • 1. Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.
    Xu T; Zhang H; Park SS; Venneti S; Kuick R; Ha K; Michael LE; Santi M; Uchida C; Uchida T; Srinivasan A; Olson JM; Dlugosz AA; Camelo-Piragua S; Rual JF
    Neoplasia; 2017 Mar; 19(3):216-225. PubMed ID: 28167297
    [TBL] [Abstract][Full Text] [Related]  

  • 2. β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
    Zinke J; Schneider FT; Harter PN; Thom S; Ziegler N; Toftgård R; Plate KH; Liebner S
    Mol Cancer; 2015 Feb; 14(1):17. PubMed ID: 25645196
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
    Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
    Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.
    Thomas WD; Chen J; Gao YR; Cheung B; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM
    Oncogene; 2009 Apr; 28(13):1605-15. PubMed ID: 19234491
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hedgehog signaling promotes medulloblastoma survival via Bc/II.
    Bar EE; Chaudhry A; Farah MH; Eberhart CG
    Am J Pathol; 2007 Jan; 170(1):347-55. PubMed ID: 17200206
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes.
    Yoon JW; Gilbertson R; Iannaccone S; Iannaccone P; Walterhouse D
    Int J Cancer; 2009 Jan; 124(1):109-19. PubMed ID: 18924150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.
    Di Marcotullio L; Ferretti E; De Smaele E; Argenti B; Mincione C; Zazzeroni F; Gallo R; Masuelli L; Napolitano M; Maroder M; Modesti A; Giangaspero F; Screpanti I; Alesse E; Gulino A
    Proc Natl Acad Sci U S A; 2004 Jul; 101(29):10833-8. PubMed ID: 15249678
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hedgehog signaling negatively co-regulates BH3-only protein Noxa and TAp73 in TP53-mutated cells.
    Meister MT; Boedicker C; Klingebiel T; Fulda S
    Cancer Lett; 2018 Aug; 429():19-28. PubMed ID: 29702195
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SMARCA4/Brg1 coordinates genetic and epigenetic networks underlying Shh-type medulloblastoma development.
    Shi X; Wang Q; Gu J; Xuan Z; Wu JI
    Oncogene; 2016 Nov; 35(44):5746-5758. PubMed ID: 27065321
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.
    Scicchitano S; Giordano M; Lucchino V; Montalcini Y; Chiarella E; Aloisio A; Codispoti B; Zoppoli P; Melocchi V; Bianchi F; De Smaele E; Mesuraca M; Morrone G; Bond HM
    Cell Death Dis; 2019 Sep; 10(10):715. PubMed ID: 31558698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
    Binning MJ; Niazi T; Pedone CA; Lal B; Eberhart CG; Kim KJ; Laterra J; Fults DW
    Cancer Res; 2008 Oct; 68(19):7838-45. PubMed ID: 18829539
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix.
    Cheng Y; Franco-Barraza J; Wang Y; Zheng C; Zhang L; Qu Y; Long Y; Cukierman E; Yang ZJ
    Lab Invest; 2020 Sep; 100(9):1208-1222. PubMed ID: 32457352
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint.
    Di Magno L; Basile A; Coni S; Manni S; Sdruscia G; D'Amico D; Antonucci L; Infante P; De Smaele E; Cucchi D; Ferretti E; Di Marcotullio L; Screpanti I; Canettieri G
    Oncotarget; 2016 Feb; 7(8):9538-49. PubMed ID: 26843621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.
    Singh AR; Joshi S; Zulcic M; Alcaraz M; Garlich JR; Morales GA; Cho YJ; Bao L; Levy ML; Newbury R; Malicki D; Messer K; Crawford J; Durden DL
    PLoS One; 2016; 11(3):e0150836. PubMed ID: 26938241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
    Faria CC; Golbourn BJ; Dubuc AM; Remke M; Diaz RJ; Agnihotri S; Luck A; Sabha N; Olsen S; Wu X; Garzia L; Ramaswamy V; Mack SC; Wang X; Leadley M; Reynaud D; Ermini L; Post M; Northcott PA; Pfister SM; Croul SE; Kool M; Korshunov A; Smith CA; Taylor MD; Rutka JT
    Cancer Res; 2015 Jan; 75(1):134-46. PubMed ID: 25391241
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional repressor REST drives lineage stage-specific chromatin compaction at
    Dobson THW; Tao RH; Swaminathan J; Maegawa S; Shaik S; Bravo-Alegria J; Sharma A; Kennis B; Yang Y; Callegari K; Haltom AR; Taylor P; Kogiso M; Qi L; Khatua S; Goldman S; Lulla RR; Fangusaro J; MacDonald TJ; Li XN; Hawkins C; Rajaram V; Gopalakrishnan V
    Sci Signal; 2019 Jan; 12(565):. PubMed ID: 30670636
    [TBL] [Abstract][Full Text] [Related]  

  • 17. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
    Dey A; Robitaille M; Remke M; Maier C; Malhotra A; Gregorieff A; Wrana JL; Taylor MD; Angers S; Kenney AM
    Oncogene; 2016 Aug; 35(32):4256-68. PubMed ID: 26725322
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.
    Wei Y; Maximov V; Morrissy SA; Taylor MD; Pallas DC; Kenney AM
    Mol Cancer Res; 2019 Jan; 17(1):186-198. PubMed ID: 30224541
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function.
    Lu J; Liu L; Zheng M; Li X; Wu A; Wu Q; Liao C; Zou J; Song H
    Oncogene; 2018 Jul; 37(28):3864-3878. PubMed ID: 29662197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PTEN loss mitigates the response of medulloblastoma to Hedgehog pathway inhibition.
    Metcalfe C; Alicke B; Crow A; Lamoureux M; Dijkgraaf GJ; Peale F; Gould SE; de Sauvage FJ
    Cancer Res; 2013 Dec; 73(23):7034-42. PubMed ID: 24154871
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.