These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 28177238)

  • 1. Design, Synthesis, and Biological Evaluation of Mitochondria-Targeted Flavone-Naphthalimide-Polyamine Conjugates with Antimetastatic Activity.
    Dai F; Li Q; Wang Y; Ge C; Feng C; Xie S; He H; Xu X; Wang C
    J Med Chem; 2017 Mar; 60(5):2071-2083. PubMed ID: 28177238
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A naphthalimide-polyamine conjugate preferentially accumulates in hepatic carcinoma metastases as a lysosome-targeted antimetastatic agent.
    Ma J; Li L; Yue K; Zhang Z; Su S; Chen Y; Yu L; Zhang P; Ma R; Li Y; Ma Y; Jia H; Wang C; Wang J; Xie S
    Eur J Med Chem; 2021 Oct; 221():113469. PubMed ID: 33965862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of naphthalimide-polyamine conjugates modified by alkylation as anticancer agents through p53 pathway.
    Dai F; He H; Xu X; Chen S; Wang C; Feng C; Tian Z; Dong H; Xie S
    Bioorg Chem; 2018 Apr; 77():16-24. PubMed ID: 29316508
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
    Wang S; Xu X; Che D; Fan R; Gao M; Cao Y; Ge C; Feng Y; Li J; Xie S; Wang C; Dai F; Gao L; Wang Y
    Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681647
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Synthesis and in vitro cytotoxicity of naphthalimide polyamine conjugates as antitumor agents].
    Mei ZH; Tian ZY; Ma HX; Xie SQ; Zhao J; Wang CJ
    Yao Xue Xue Bao; 2009 Jul; 44(7):754-7. PubMed ID: 19806915
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3-Nitro-naphthalimide and nitrogen mustard conjugate NNM-25 induces hepatocellular carcinoma apoptosis via PARP-1/p53 pathway.
    Xie SQ; Zhang YH; Li Q; Xu FH; Miao JW; Zhao J; Wang CJ
    Apoptosis; 2012 Jul; 17(7):725-34. PubMed ID: 22395446
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conjugation of substituted naphthalimides to polyamines as cytotoxic agents targeting the Akt/mTOR signal pathway.
    Tian ZY; Xie SQ; Mei ZH; Zhao J; Gao WY; Wang CJ
    Org Biomol Chem; 2009 Nov; 7(22):4651-60. PubMed ID: 19865701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents.
    Tian ZY; Xie SQ; Du YW; Ma YF; Zhao J; Gao WY; Wang CJ
    Eur J Med Chem; 2009 Jan; 44(1):393-9. PubMed ID: 18423800
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BND-12, a novel nonhaematotoxic naphthalimide derivative, inhibits tumour growth and metastasis of hepatocellular carcinoma.
    Xie SQ; Li Q; Zhang YH; Li Z; Zhao J; Wang CJ
    J Pharm Pharmacol; 2012 Oct; 64(10):1483-90. PubMed ID: 22943179
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A ROS-mediated lysosomal-mitochondrial pathway is induced by a novel Amonafide analogue, 7c, in human Hela cervix carcinoma cells.
    Shen K; Sun L; Zhang H; Xu Y; Qian X; Lu Y; Li Q; Ni L; Liu J
    Cancer Lett; 2013 Jun; 333(2):229-38. PubMed ID: 23376642
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological properties of polyamine modified flavonoids as hepatocellular carcinoma inhibitors.
    Li Q; Zhai Y; Luo W; Zhu Z; Zhang X; Xie S; Hong C; Wang Y; Su Y; Zhao J; Wang C
    Eur J Med Chem; 2016 Oct; 121():110-119. PubMed ID: 27236067
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of novel amonafide-polyamine conjugates as anticancer agents.
    Wang Y; Zhang J; Li M; Li M; Xie S; Wang C
    Chem Biol Drug Des; 2017 May; 89(5):670-680. PubMed ID: 27762101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of the Polyamine Conjugate with Benzo[ cd]indol-2(1 H)-one as a Lysosome-Targeted Antimetastatic Agent.
    Li J; Tian R; Ge C; Chen Y; Liu X; Wang Y; Yang Y; Luo W; Dai F; Wang S; Chen S; Xie S; Wang C
    J Med Chem; 2018 Aug; 61(15):6814-6829. PubMed ID: 29990424
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and Biological Evaluation of Novel Aromatic Imide-Polyamine Conjugates.
    Li M; Wang Y; Zhang J; Xie S; Wang C; Wu Y
    Molecules; 2016 Nov; 21(12):. PubMed ID: 27916902
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suppression of oxidative phosphorylation and IDH2 sensitizes colorectal cancer to a naphthalimide derivative and mitoxantrone.
    Ge C; Wang Y; Feng Y; Wang S; Zhang K; Xu X; Zhang Z; Zhao Y; Wang Y; Gao L; Dai F; Xie S; Wang C
    Cancer Lett; 2021 Oct; 519():30-45. PubMed ID: 34166768
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reactive oxygen species (ROS) accumulation induced by mononaphthalimide-spermidine leads to intrinsic and AIF-mediated apoptosis in HeLa cells.
    Yang L; Zhao J; Zhu Y; Tian Z; Wang C
    Oncol Rep; 2011 Apr; 25(4):1099-107. PubMed ID: 21290091
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor effects and preliminary systemic toxicity of ANISpm in vivo and in vitro.
    Li M; Li Q; Zhang YH; Tian ZY; Ma HX; Zhao J; Xie SQ; Wang CJ
    Anticancer Drugs; 2013 Jan; 24(1):32-42. PubMed ID: 23032518
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Acetylsalicylic acid strengthens the effects of ANISpm against hepatocellular carcinoma and its molecular mechanism].
    Xie SQ; Zhang LL; Yang T; Ma Y; Zhang YH; Li Q; Wang JH; Zhao J; Wang CJ
    Yao Xue Xue Bao; 2011 Sep; 46(9):1045-50. PubMed ID: 22121773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 7-b, a novel amonafide analogue, cause growth inhibition and apoptosis in Raji cells via a ROS-mediated mitochondrial pathway.
    Lin B; Chen Z; Xu Y; Zhang H; Liu J; Qian X
    Leuk Res; 2011 May; 35(5):646-56. PubMed ID: 21310484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Polyamine-Based Dinitro-Naphthalimide Conjugate as Substrates for Polyamine Transporters Preferentially Accumulates in Cancer Cells and Minimizes Side Effects
    Ma J; Li Y; Li L; Yue K; Liu H; Wang J; Xi Z; Shi M; Zhao S; Ma Q; Liu S; Guo S; Liu J; Hou L; Wang C; Wang PG; Tian Z; Xie S
    Front Chem; 2020; 8():166. PubMed ID: 32328475
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.