BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 28177250)

  • 1. Synthesis of Biologically Active Indenoisoquinoline Derivatives via a One-Pot Copper(II)-Catalyzed Tandem Reaction.
    Huang CY; Kavala V; Kuo CW; Konala A; Yang TH; Yao CF
    J Org Chem; 2017 Feb; 82(4):1961-1968. PubMed ID: 28177250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Optimization of the indenone ring of indenoisoquinoline topoisomerase I inhibitors.
    Morrell A; Placzek M; Parmley S; Grella B; Antony S; Pommier Y; Cushman M
    J Med Chem; 2007 Sep; 50(18):4388-404. PubMed ID: 17676830
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rhodium-catalyzed synthesis of isoquinolines and indenes from benzylidenehydrazones and internal alkynes.
    Huang XC; Yang XH; Song RJ; Li JH
    J Org Chem; 2014 Feb; 79(3):1025-31. PubMed ID: 24417252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Copper-Catalyzed Tandem Reactions for Synthesis of Pyrazolo[5,1-a]isoquinolines with Heterocyclic Ketene Aminals as Ligands.
    Wen LR; Jin XJ; Niu XD; Li M
    J Org Chem; 2015 Jan; 80(1):90-8. PubMed ID: 25426845
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Green method for the synthesis of highly substituted cyclohexa-1,3-diene, polyhydroindene, polyhydronaphthalene, isochromene, isothiochromene, and isoquinoline derivatives in ionic liquids.
    Wang XS; Wu JR; Zhou J; Tu SJ
    J Comb Chem; 2009; 11(6):1011-22. PubMed ID: 19764713
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Route to pyrazolo[5,1-a]isoquinolines via a copper-catalyzed tandem reaction of 2-alkynylbromobenzene with pyrazole.
    Pan X; Luo Y; Wu J
    J Org Chem; 2013 Jun; 78(11):5756-60. PubMed ID: 23688087
    [TBL] [Abstract][Full Text] [Related]  

  • 7. One pot synthesis of indene through copper(I)-catalyzed three-components coupling and cyclization reaction.
    Wang XC; Zhong MJ; Liang YM
    Org Biomol Chem; 2012 May; 10(18):3636-41. PubMed ID: 22495439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sequential Cu(I)/Pd(0)-catalyzed multicomponent coupling and annulation protocol for the synthesis of indenoisoquinolines.
    Jayanth TT; Zhang L; Johnson TS; Malinakova HC
    Org Lett; 2009 Feb; 11(4):815-8. PubMed ID: 19159326
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons.
    Beck DE; Lv W; Abdelmalak M; Plescia CB; Agama K; Marchand C; Pommier Y; Cushman M
    Bioorg Med Chem; 2016 Apr; 24(7):1469-79. PubMed ID: 26906474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of dibenzoxepine lactams via a Cu-catalyzed one-pot etherification/aldol condensation cascade reaction: application toward the total synthesis of aristoyagonine.
    Lim HS; Choi YL; Heo JN
    Org Lett; 2013 Sep; 15(18):4718-21. PubMed ID: 24000941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of functionalized indenes via cascade reaction of aziridines and propargyl alcohols.
    Wang S; Zhu Y; Wang Y; Lu P
    Org Lett; 2009 Jun; 11(12):2615-8. PubMed ID: 19449884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of functionalized 1H-indenes via copper-catalyzed arylative cyclization of arylalkynes with aromatic sulfonyl chlorides.
    Zeng X; Ilies L; Nakamura E
    J Am Chem Soc; 2011 Nov; 133(44):17638-40. PubMed ID: 21988538
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Concise copper-catalyzed one-pot tandem synthesis of benzimidazo[1,2-b]isoquinolin-11-one derivatives.
    Lu J; Gong X; Yang H; Fu H
    Chem Commun (Camb); 2010 Jun; 46(23):4172-4. PubMed ID: 20527726
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nitrated indenoisoquinolines as topoisomerase I inhibitors: a systematic study and optimization.
    Morrell A; Placzek M; Parmley S; Antony S; Dexheimer TS; Pommier Y; Cushman M
    J Med Chem; 2007 Sep; 50(18):4419-30. PubMed ID: 17696418
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Investigation of the lactam side chain length necessary for optimal indenoisoquinoline topoisomerase I inhibition and cytotoxicity in human cancer cell cultures.
    Morrell A; Placzek MS; Steffen JD; Antony S; Agama K; Pommier Y; Cushman M
    J Med Chem; 2007 May; 50(9):2040-8. PubMed ID: 17402722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and biological evaluation of indenoisoquinoline topoisomerase I inhibitors featuring polyamine side chains on the lactam nitrogen.
    Nagarajan M; Xiao X; Antony S; Kohlhagen G; Pommier Y; Cushman M
    J Med Chem; 2003 Dec; 46(26):5712-24. PubMed ID: 14667224
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Application of sequential Cu(I)/Pd(0)-catalysis to solution-phase parallel synthesis of combinatorial libraries of dihydroindeno[1,2-c]isoquinolines.
    Kumar S; Painter TO; Pal BK; Neuenswander B; Malinakova HC
    ACS Comb Sci; 2011 Sep; 13(5):466-77. PubMed ID: 21528920
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tandem C-C coupling--intramolecular acetylenic Schmidt reaction under Pd/C-Cu catalysis.
    Batchu VR; Barange DK; Kumar D; Sreekanth BR; Vyas K; Reddy EA; Pal M
    Chem Commun (Camb); 2007 May; (19):1966-8. PubMed ID: 17695245
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A copper-catalyzed tandem synthesis of indolo- and pyrrolo[2,1-a]isoquinolines.
    Verma AK; Kesharwani T; Singh J; Tandon V; Larock RC
    Angew Chem Int Ed Engl; 2009; 48(6):1138-43. PubMed ID: 19115342
    [No Abstract]   [Full Text] [Related]  

  • 20. An efficient one-pot copper-catalyzed approach to isoquinolin-1(2H)-one derivatives.
    Wang F; Liu H; Fu H; Jiang Y; Zhao Y
    Org Lett; 2009 Jun; 11(11):2469-72. PubMed ID: 19422263
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.