BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 28180284)

  • 1. Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.
    Gillinder KR; Ilsley MD; Nébor D; Sachidanandam R; Lajoie M; Magor GW; Tallack MR; Bailey T; Landsberg MJ; Mackay JP; Parker MW; Miles LA; Graber JH; Peters LL; Bieker JJ; Perkins AC
    Nucleic Acids Res; 2017 Feb; 45(3):1130-1143. PubMed ID: 28180284
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors.
    Ilsley MD; Huang S; Magor GW; Landsberg MJ; Gillinder KR; Perkins AC
    BMC Genomics; 2019 May; 20(1):417. PubMed ID: 31126231
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis.
    Nébor D; Graber JH; Ciciotte SL; Robledo RF; Papoin J; Hartman E; Gillinder KR; Perkins AC; Bieker JJ; Blanc L; Peters LL
    Sci Rep; 2018 Aug; 8(1):12793. PubMed ID: 30143664
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.
    Siatecka M; Sahr KE; Andersen SG; Mezei M; Bieker JJ; Peters LL
    Proc Natl Acad Sci U S A; 2010 Aug; 107(34):15151-6. PubMed ID: 20696915
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A
    Kulczynska K; Bieker JJ; Siatecka M
    Mol Cell Biol; 2020 Feb; 40(5):. PubMed ID: 31818881
    [TBL] [Abstract][Full Text] [Related]  

  • 6. EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release.
    Mukherjee K; Bieker JJ
    Cell Rep; 2022 Dec; 41(12):111830. PubMed ID: 36543143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Severe anemia caused by dominant mutations in Krüppel-like factor 1 (KLF1).
    Kulczynska-Figurny K; Bieker JJ; Siatecka M
    Mutat Res Rev Mutat Res; 2020; 786():108336. PubMed ID: 33339573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Compound heterozygosity for KLF1 mutations is associated with microcytic hypochromic anemia and increased fetal hemoglobin.
    Huang J; Zhang X; Liu D; Wei X; Shang X; Xiong F; Yu L; Yin X; Xu X
    Eur J Hum Genet; 2015 Oct; 23(10):1341-8. PubMed ID: 25585695
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation in erythroid specific transcription factor KLF1 causes Hereditary Spherocytosis in the Nan hemolytic anemia mouse model.
    Heruth DP; Hawkins T; Logsdon DP; Gibson MI; Sokolovsky IV; Nsumu NN; Major SL; Fegley B; Woods GM; Lewing KB; Neville KA; Cornetta K; Peterson KR; White RA
    Genomics; 2010 Nov; 96(5):303-7. PubMed ID: 20691777
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation.
    Schuetz A; Nana D; Rose C; Zocher G; Milanovic M; Koenigsmann J; Blasig R; Heinemann U; Carstanjen D
    Cell Mol Life Sci; 2011 Sep; 68(18):3121-31. PubMed ID: 21290164
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes.
    Singleton BK; Lau W; Fairweather VS; Burton NM; Wilson MC; Parsons SF; Richardson BM; Trakarnsanga K; Brady RL; Anstee DJ; Frayne J
    Blood; 2011 Sep; 118(11):3137-45. PubMed ID: 21778342
    [TBL] [Abstract][Full Text] [Related]  

  • 12. KLF1 directly coordinates almost all aspects of terminal erythroid differentiation.
    Tallack MR; Perkins AC
    IUBMB Life; 2010 Dec; 62(12):886-90. PubMed ID: 21190291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch.
    Norton LJ; Hallal S; Stout ES; Funnell APW; Pearson RCM; Crossley M; Quinlan KGR
    Sci Rep; 2017 Jun; 7(1):3137. PubMed ID: 28600522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bioinformatics analysis of non-synonymous variants in the KLF genes related to cardiac diseases.
    Ferreira KKS; de Morais Gomes ER; de Lima Filho JL; Castelletti CHM; Martins DBG
    Gene; 2018 Apr; 650():68-76. PubMed ID: 29408733
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The mammalian zinc finger transcription factor Krüppel-like factor 3 (KLF3/BKLF).
    Pearson RC; Funnell AP; Crossley M
    IUBMB Life; 2011 Feb; 63(2):86-93. PubMed ID: 21360637
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Krüppel-like factors compete for promoters and enhancers to fine-tune transcription.
    Ilsley MD; Gillinder KR; Magor GW; Huang S; Bailey TL; Crossley M; Perkins AC
    Nucleic Acids Res; 2017 Jun; 45(11):6572-6588. PubMed ID: 28541545
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development.
    Sun L; Liu A; Georgopoulos K
    EMBO J; 1996 Oct; 15(19):5358-69. PubMed ID: 8895580
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development.
    Planutis A; Xue L; Trainor CD; Dangeti M; Gillinder K; Siatecka M; Nebor D; Peters LL; Perkins AC; Bieker JJ
    Development; 2017 Feb; 144(3):430-440. PubMed ID: 28143845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation.
    Cantú I; van de Werken HJG; Gillemans N; Stadhouders R; Heshusius S; Maas A; Esteghamat F; Ozgur Z; van IJcken WFJ; Grosveld F; von Lindern M; Philipsen S; van Dijk TB
    PLoS One; 2019; 14(3):e0208659. PubMed ID: 30921348
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain.
    Lim WF; Burdach J; Funnell AP; Pearson RC; Quinlan KG; Crossley M
    Nucleic Acids Res; 2016 Apr; 44(7):3118-30. PubMed ID: 26673701
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.