BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 28182003)

  • 1. Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1.
    Song S; Su Z; Xu H; Niu M; Chen X; Min H; Zhang B; Sun G; Xie S; Wang H; Gao Q
    Cell Death Dis; 2017 Feb; 8(2):e2612. PubMed ID: 28182003
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells.
    Liu CY; Su JC; Ni MH; Tseng LM; Chu PY; Wang DS; Tai WT; Kao YP; Hung MH; Shiau CW; Chen KF
    Breast Cancer Res Treat; 2014 Jul; 146(1):71-84. PubMed ID: 24903225
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells.
    Su JC; Tseng PH; Hsu CY; Tai WT; Huang JW; Ko CH; Lin MW; Liu CY; Chen KF; Shiau CW
    Oncotarget; 2014 Jul; 5(13):4909-19. PubMed ID: 24952874
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
    Chen KF; Chen HL; Liu CY; Tai WT; Ichikawa K; Chen PJ; Cheng AL
    Biochem Pharmacol; 2012 Mar; 83(6):769-77. PubMed ID: 22230479
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids.
    Selvendiran K; Koga H; Ueno T; Yoshida T; Maeyama M; Torimura T; Yano H; Kojiro M; Sata M
    Cancer Res; 2006 May; 66(9):4826-34. PubMed ID: 16651438
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation.
    Chen KF; Su JC; Liu CY; Huang JW; Chen KC; Chen WL; Tai WT; Shiau CW
    Cancer Lett; 2012 Aug; 321(1):27-35. PubMed ID: 22465052
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells.
    Liu CY; Huang TT; Chu PY; Huang CT; Lee CH; Wang WL; Lau KY; Tsai WC; Chao TI; Su JC; Chen MH; Shiau CW; Tseng LM; Chen KF
    Exp Mol Med; 2017 Aug; 49(8):e366. PubMed ID: 28798401
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells.
    Kim SH; Yoo HS; Joo MK; Kim T; Park JJ; Lee BJ; Chun HJ; Lee SW; Bak YT
    BMC Cancer; 2018 Feb; 18(1):150. PubMed ID: 29409467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A derivative of epigallocatechin-3-gallate induces apoptosis via SHP-1-mediated suppression of BCR-ABL and STAT3 signalling in chronic myelogenous leukaemia.
    Jung JH; Yun M; Choo EJ; Kim SH; Jeong MS; Jung DB; Lee H; Kim EO; Kato N; Kim B; Srivastava SK; Kaihatsu K; Kim SH
    Br J Pharmacol; 2015 Jul; 172(14):3565-78. PubMed ID: 25825203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Luteolin alleviates ulcerative colitis through SHP-1/STAT3 pathway.
    Li BL; Zhao DY; Du PL; Wang XT; Yang Q; Cai YR
    Inflamm Res; 2021 Jun; 70(6):705-717. PubMed ID: 34014331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Verbascoside Inhibits Glioblastoma Cell Proliferation, Migration and Invasion While Promoting Apoptosis Through Upregulation of Protein Tyrosine Phosphatase SHP-1 and Inhibition of STAT3 Phosphorylation.
    Jia WQ; Wang ZT; Zou MM; Lin JH; Li YH; Zhang L; Xu RX
    Cell Physiol Biochem; 2018; 47(5):1871-1882. PubMed ID: 29961065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase.
    Kim C; Cho SK; Kapoor S; Kumar A; Vali S; Abbasi T; Kim SH; Sethi G; Ahn KS
    Mol Carcinog; 2014 Oct; 53(10):793-806. PubMed ID: 23765383
    [TBL] [Abstract][Full Text] [Related]  

  • 13. WMJ-8-B, a novel hydroxamate derivative, induces MDA-MB-231 breast cancer cell death via the SHP-1-STAT3-survivin cascade.
    Chuang YF; Huang SW; Hsu YF; Yu MC; Ou G; Huang WJ; Hsu MJ
    Br J Pharmacol; 2017 Sep; 174(17):2941-2961. PubMed ID: 28646512
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression.
    Wang W; Zhan M; Li Q; Chen W; Chu H; Huang Q; Hou Z; Man M; Wang J
    Oncotarget; 2016 Jun; 7(23):34617-29. PubMed ID: 27127878
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells.
    Yang J; Cai X; Lu W; Hu C; Xu X; Yu Q; Cao P
    Cancer Lett; 2013 Jan; 328(2):243-51. PubMed ID: 23032719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Luteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3.
    Fu J; Chen D; Zhao B; Zhao Z; Zhou J; Xu Y; Xin Y; Liu C; Luo L; Yin Z
    PLoS One; 2012; 7(11):e49194. PubMed ID: 23145121
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway.
    Wang J; Zhang L; Chen G; Zhang J; Li Z; Lu W; Liu M; Pang X
    Breast Cancer Res Treat; 2014 Nov; 148(2):279-89. PubMed ID: 25301089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inactivation of HDAC3 and STAT3 is critically involved in 1-stearoyl-sn-glycero-3-phosphocholine-induced apoptosis in chronic myelogenous leukemia K562 cells.
    Jung JH; Jeong SJ; Kim JH; Jung SK; Jung DB; Lee D; Sohn EJ; Yun M; Lee HJ; Lee HJ; Kim SH
    Cell Biochem Biophys; 2013; 67(3):1379-89. PubMed ID: 23729004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer.
    Lu J; Li G; He K; Jiang W; Xu C; Li Z; Wang H; Wang W; Wang H; Teng X; Teng L
    J Transl Med; 2015 Feb; 13():42. PubMed ID: 25638174
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Signal transducer and activator of transcription 3 as molecular therapy for non-small-cell lung cancer.
    Wang CY; Chao TT; Tai WT; Chang FY; Su WP; Chen YL; Chen PT; Weng CY; Yuan A; Shiau CW; Yu CJ; Chen KF
    J Thorac Oncol; 2014 Apr; 9(4):488-96. PubMed ID: 24736071
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.