BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 28182747)

  • 41. Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma.
    Fung KM; Samara EN; Wong C; Metwalli A; Krlin R; Bane B; Liu CZ; Yang JT; Pitha JV; Culkin DJ; Kropp BP; Penning TM; Lin HK
    Endocr Relat Cancer; 2006 Mar; 13(1):169-80. PubMed ID: 16601286
    [TBL] [Abstract][Full Text] [Related]  

  • 42. The Curcumin Derivative, H10, Suppresses Hormone-Dependent Prostate Cancer by Inhibiting 17β-Hydroxysteroid Dehydrogenase Type 3.
    Cheng Y; Yang Y; Wu Y; Wang W; Xiao L; Zhang Y; Tang J; Huang YD; Zhang S; Xiang Q
    Front Pharmacol; 2020; 11():637. PubMed ID: 32457626
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.
    Xu Y; Dalrymple SL; Becker RE; Denmeade SR; Isaacs JT
    Clin Cancer Res; 2006 Jul; 12(13):4072-9. PubMed ID: 16818707
    [TBL] [Abstract][Full Text] [Related]  

  • 44. The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase.
    Legeza B; Balázs Z; Nashev LG; Odermatt A
    Endocrinology; 2013 Jan; 154(1):205-13. PubMed ID: 23183177
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3.
    Vicker N; Bailey HV; Day JM; Mahon MF; Smith A; Tutill HJ; Purohit A; Potter BVL
    Molecules; 2021 Nov; 26(23):. PubMed ID: 34885749
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer.
    Aka JA; Mazumdar M; Lin SX
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):183-90. PubMed ID: 19038308
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Design, synthesis and in vitro evaluation of 4-androstene-3,17-dione/adenosine hybrid compounds as bisubstrate inhibitors of type 3 17beta-hydroxysteroid dehydrogenase.
    Bérubé M; Laplante Y; Poirier D
    Med Chem; 2006 Jul; 2(4):329-47. PubMed ID: 16848745
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Discovery of potent and orally bioavailable 17β-hydroxysteroid dehydrogenase type 3 inhibitors.
    Harada K; Kubo H; Abe J; Haneta M; Conception A; Inoue S; Okada S; Nishioka K
    Bioorg Med Chem; 2012 May; 20(10):3242-54. PubMed ID: 22512907
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Novel, potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors as potential therapeutics for osteoporosis with dual human and mouse activities.
    Perspicace E; Cozzoli L; Gargano EM; Hanke N; Carotti A; Hartmann RW; Marchais-Oberwinkler S
    Eur J Med Chem; 2014 Aug; 83():317-37. PubMed ID: 24974351
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer.
    Harada K; Kubo H; Tomigahara Y; Nishioka K; Takahashi J; Momose M; Inoue S; Kojima A
    Bioorg Med Chem Lett; 2010 Jan; 20(1):272-5. PubMed ID: 19954971
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Reductase activity of 17beta-hydroxysteroid oxidoreductase in prostatic tumors of different histological structure.
    Degtyar VG; Babkina TV; Kazantseva IA; Morozov AP; Trapeznikova MF; Kushlinskii NE
    Bull Exp Biol Med; 2005 Jun; 139(6):715-7. PubMed ID: 16224590
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Chemical synthesis and in vitro biological evaluation of a phosphorylated bisubstrate inhibitor of type 3 17beta-hydroxysteroid dehydrogenase.
    Bérubé M; Poirier D
    J Enzyme Inhib Med Chem; 2007 Apr; 22(2):201-11. PubMed ID: 17518347
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry.
    El-Alfy M; Luu-The V; Huang XF; Berger L; Labrie F; Pelletier G
    Endocrinology; 1999 Mar; 140(3):1481-91. PubMed ID: 10067877
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Impact of structural modifications at positions 13, 16 and 17 of 16β-(m-carbamoylbenzyl)-estradiol on 17β-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity.
    Maltais R; Trottier A; Barbeau X; Lagüe P; Perreault M; Thériault JF; Lin SX; Poirier D
    J Steroid Biochem Mol Biol; 2016 Jul; 161():24-35. PubMed ID: 26519987
    [TBL] [Abstract][Full Text] [Related]  

  • 55. 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development.
    Marchais-Oberwinkler S; Henn C; Möller G; Klein T; Negri M; Oster A; Spadaro A; Werth R; Wetzel M; Xu K; Frotscher M; Hartmann RW; Adamski J
    J Steroid Biochem Mol Biol; 2011 May; 125(1-2):66-82. PubMed ID: 21193039
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution.
    Lin HK; Jez JM; Schlegel BP; Peehl DM; Pachter JA; Penning TM
    Mol Endocrinol; 1997 Dec; 11(13):1971-84. PubMed ID: 9415401
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Androsterone derivatives substituted at position 16: chemical synthesis, inhibition of type 3 17beta-hydroxysteroid dehydrogenase, binding affinity for steroid receptors and proliferative/antiproliferative activity on Shionogi (AR+) cells.
    Tchédam-Ngatcha B; Luu-The V; Poirier D
    J Enzyme Inhib Med Chem; 2002 Jun; 17(3):155-65. PubMed ID: 12443041
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Curcumin derivatives inhibit testicular 17beta-hydroxysteroid dehydrogenase 3.
    Hu GX; Liang G; Chu Y; Li X; Lian QQ; Lin H; He Y; Huang Y; Hardy DO; Ge RS
    Bioorg Med Chem Lett; 2010 Apr; 20(8):2549-51. PubMed ID: 20346654
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Inhibition of human and rat 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities by perfluoroalkylated substances.
    Zhao B; Hu GX; Chu Y; Jin X; Gong S; Akingbemi BT; Zhang Z; Zirkin BR; Ge RS
    Chem Biol Interact; 2010 Oct; 188(1):38-43. PubMed ID: 20619251
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease.
    Bauman DR; Steckelbroeck S; Williams MV; Peehl DM; Penning TM
    Mol Endocrinol; 2006 Feb; 20(2):444-58. PubMed ID: 16179381
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.