BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 28188785)

  • 1. Sortilin-related receptor 1 interacts with amyloid precursor protein and is activated by 6-shogaol, leading to inhibition of the amyloidogenic pathway.
    Na JY; Song K; Lee JW; Kim S; Kwon J
    Biochem Biophys Res Commun; 2017 Mar; 484(4):890-895. PubMed ID: 28188785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.
    Huang TY; Zhao Y; Li X; Wang X; Tseng IC; Thompson R; Tu S; Willnow TE; Zhang YW; Xu H
    J Neurosci; 2016 Jul; 36(30):7996-8011. PubMed ID: 27466343
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing.
    Knupp A; Mishra S; Martinez R; Braggin JE; Szabo M; Kinoshita C; Hailey DW; Small SA; Jayadev S; Young JE
    Cell Rep; 2020 Jun; 31(9):107719. PubMed ID: 32492427
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 6-Shogaol has anti-amyloidogenic activity and ameliorates Alzheimer's disease via CysLT1R-mediated inhibition of cathepsin B.
    Na JY; Song K; Lee JW; Kim S; Kwon J
    Biochem Biophys Res Commun; 2016 Aug; 477(1):96-102. PubMed ID: 27286707
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex.
    Lane RF; Raines SM; Steele JW; Ehrlich ME; Lah JA; Small SA; Tanzi RE; Attie AD; Gandy S
    J Neurosci; 2010 Sep; 30(39):13110-5. PubMed ID: 20881129
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Role of SORL1 in Alzheimer's Disease.
    Yin RH; Yu JT; Tan L
    Mol Neurobiol; 2015; 51(3):909-18. PubMed ID: 24833601
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Alzheimer's gene SORL1 is a regulator of endosomal traffic and recycling in human neurons.
    Mishra S; Knupp A; Szabo MP; Williams CA; Kinoshita C; Hailey DW; Wang Y; Andersen OM; Young JE
    Cell Mol Life Sci; 2022 Feb; 79(3):162. PubMed ID: 35226190
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
    Andersen OM; Reiche J; Schmidt V; Gotthardt M; Spoelgen R; Behlke J; von Arnim CA; Breiderhoff T; Jansen P; Wu X; Bales KR; Cappai R; Masters CL; Gliemann J; Mufson EJ; Hyman BT; Paul SM; Nykjaer A; Willnow TE
    Proc Natl Acad Sci U S A; 2005 Sep; 102(38):13461-6. PubMed ID: 16174740
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele.
    Zollo A; Allen Z; Rasmussen HF; Iannuzzi F; Shi Y; Larsen A; Maier TJ; Matrone C
    Neural Plast; 2017; 2017():1892612. PubMed ID: 28634550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SORLA/SORL1, a neuronal sorting receptor implicated in Alzheimer's disease.
    Willnow TE; Carlo AS; Rohe M; Schmidt V
    Rev Neurosci; 2010; 21(4):315-29. PubMed ID: 21086763
    [TBL] [Abstract][Full Text] [Related]  

  • 12. APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.
    Maulik M; Peake K; Chung J; Wang Y; Vance JE; Kar S
    Hum Mol Genet; 2015 Dec; 24(24):7132-50. PubMed ID: 26433932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
    Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network.
    Hung C; Tuck E; Stubbs V; van der Lee SJ; Aalfs C; van Spaendonk R; Scheltens P; Hardy J; Holstege H; Livesey FJ
    Cell Rep; 2021 Jun; 35(11):109259. PubMed ID: 34133918
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome.
    Lee JH; Chulikavit M; Pang D; Zigman WB; Silverman W; Schupf N
    Neurosci Lett; 2007 Sep; 425(2):105-9. PubMed ID: 17826910
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription.
    Li Y; Zhou W; Tong Y; He G; Song W
    FASEB J; 2006 Feb; 20(2):285-92. PubMed ID: 16449801
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Double-Edged Roles of Nitric Oxide Signaling on APP Processing and Amyloid-β Production In Vitro: Preliminary Evidence from Sodium Nitroprusside.
    Cai ZX; Guo HS; Wang C; Wei M; Cheng C; Yang ZF; Chen YW; Le WD; Li S
    Neurotox Res; 2016 Jan; 29(1):21-34. PubMed ID: 26429731
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S; Refolo LM; Sambamurti K
    J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hydrogen Sulfide Selectively Inhibits γ-Secretase Activity and Decreases Mitochondrial Aβ Production in Neurons from APP/PS1 Transgenic Mice.
    Zhao FL; Qiao PF; Yan N; Gao D; Liu MJ; Yan Y
    Neurochem Res; 2016 May; 41(5):1145-59. PubMed ID: 26708452
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.
    Fu H; Dou J; Li W; Cui W; Mak S; Hu Q; Luo J; Lam CS; Pang Y; Youdim MB; Han Y
    Eur J Pharmacol; 2009 Nov; 623(1-3):14-21. PubMed ID: 19765582
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.