BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 28192085)

  • 1. Influence of peptide transporter 2 (PEPT2) on the distribution of cefadroxil in mouse brain: A microdialysis study.
    Chen X; Keep RF; Liang Y; Zhu HJ; Hammarlund-Udenaes M; Hu Y; Smith DE
    Biochem Pharmacol; 2017 May; 131():89-97. PubMed ID: 28192085
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption, and brain penetration in mice.
    Shen H; Ocheltree SM; Hu Y; Keep RF; Smith DE
    Drug Metab Dispos; 2007 Jul; 35(7):1209-16. PubMed ID: 17452417
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PEPT2 (Slc15a2)-mediated unidirectional transport of cefadroxil from cerebrospinal fluid into choroid plexus.
    Shen H; Keep RF; Hu Y; Smith DE
    J Pharmacol Exp Ther; 2005 Dec; 315(3):1101-8. PubMed ID: 16107517
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of transporter inhibition on the distribution of cefadroxil in rat brain.
    Chen X; Loryan I; Payan M; Keep RF; Smith DE; Hammarlund-Udenaes M
    Fluids Barriers CNS; 2014; 11(1):25. PubMed ID: 25414790
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of cefadroxil uptake in the choroid plexus: studies in wild-type and PEPT2 knockout mice.
    Ocheltree SM; Shen H; Hu Y; Xiang J; Keep RF; Smith DE
    J Pharmacol Exp Ther; 2004 Feb; 308(2):462-7. PubMed ID: 14600253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distribution of glycylsarcosine and cefadroxil among cerebrospinal fluid, choroid plexus, and brain parenchyma after intracerebroventricular injection is markedly different between wild-type and Pept2 null mice.
    Smith DE; Hu Y; Shen H; Nagaraja TN; Fenstermacher JD; Keep RF
    J Cereb Blood Flow Metab; 2011 Jan; 31(1):250-61. PubMed ID: 20571525
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice.
    Ocheltree SM; Shen H; Hu Y; Keep RF; Smith DE
    J Pharmacol Exp Ther; 2005 Oct; 315(1):240-7. PubMed ID: 15987832
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role and relevance of PEPT2 in drug disposition, dynamics, and toxicity.
    Kamal MA; Keep RF; Smith DE
    Drug Metab Pharmacokinet; 2008; 23(4):236-42. PubMed ID: 18762710
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice.
    Hu Y; Smith DE
    Biochem Pharmacol; 2016 May; 107():81-90. PubMed ID: 26979860
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Species Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants.
    Song F; Hu Y; Jiang H; Smith DE
    Drug Metab Dispos; 2017 Feb; 45(2):130-136. PubMed ID: 27836942
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Influence of genetic knockout of Pept2 on the in vivo disposition of endogenous and exogenous carnosine in wild-type and Pept2 null mice.
    Kamal MA; Jiang H; Hu Y; Keep RF; Smith DE
    Am J Physiol Regul Integr Comp Physiol; 2009 Apr; 296(4):R986-91. PubMed ID: 19225147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Population pharmacokinetic modeling of cefadroxil renal transport in wild-type and Pept2 knockout mice.
    Xie Y; Shen H; Hu Y; Feng MR; Smith DE
    Xenobiotica; 2016; 46(4):342-9. PubMed ID: 26372256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vivo absorption and disposition of cefadroxil after escalating oral doses in wild-type and PepT1 knockout mice.
    Posada MM; Smith DE
    Pharm Res; 2013 Nov; 30(11):2931-9. PubMed ID: 23959853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeted disruption of the PEPT2 gene markedly reduces dipeptide uptake in choroid plexus.
    Shen H; Smith DE; Keep RF; Xiang J; Brosius FC
    J Biol Chem; 2003 Feb; 278(7):4786-91. PubMed ID: 12473671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relevance of PepT1 in the intestinal permeability and oral absorption of cefadroxil.
    Posada MM; Smith DE
    Pharm Res; 2013 Apr; 30(4):1017-25. PubMed ID: 23224978
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression and function of PEPT2 during transdifferentiation of alveolar epithelial cells.
    Takano M; Horiuchi T; Sasaki Y; Kato Y; Nagai J; Yumoto R
    Life Sci; 2013 Oct; 93(17):630-6. PubMed ID: 23988852
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Peptide transporter 2 (PEPT2) expression in brain protects against 5-aminolevulinic acid neurotoxicity.
    Hu Y; Shen H; Keep RF; Smith DE
    J Neurochem; 2007 Dec; 103(5):2058-65. PubMed ID: 17854384
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Immunolocalization of the proton-coupled oligopeptide transporter PEPT2 in developing rat brain.
    Shen H; Smith DE; Keep RF; Brosius FC
    Mol Pharm; 2004; 1(4):248-56. PubMed ID: 15981584
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impact of lipopolysaccharide-induced inflammation on the disposition of the aminocephalosporin cefadroxil.
    Huh Y; Keep RF; Smith DE
    Antimicrob Agents Chemother; 2013 Dec; 57(12):6171-8. PubMed ID: 24080658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of 5-aminolevulinic acid uptake at the choroid plexus.
    Novotny A; Xiang J; Stummer W; Teuscher NS; Smith DE; Keep RF
    J Neurochem; 2000 Jul; 75(1):321-8. PubMed ID: 10854277
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.