BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 28192171)

  • 1. A new light on Alkaptonuria: A Fourier-transform infrared microscopy (FTIRM) and low energy X-ray fluorescence (LEXRF) microscopy correlative study on a rare disease.
    Mitri E; Millucci L; Merolle L; Bernardini G; Vaccari L; Gianoncelli A; Santucci A
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt A):1000-1008. PubMed ID: 28192171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alkaptonuria is a novel human secondary amyloidogenic disease.
    Millucci L; Spreafico A; Tinti L; Braconi D; Ghezzi L; Paccagnini E; Bernardini G; Amato L; Laschi M; Selvi E; Galeazzi M; Mannoni A; Benucci M; Lupetti P; Chellini F; Orlandini M; Santucci A
    Biochim Biophys Acta; 2012 Nov; 1822(11):1682-91. PubMed ID: 22850426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloidosis in alkaptonuria.
    Millucci L; Braconi D; Bernardini G; Lupetti P; Rovensky J; Ranganath L; Santucci A
    J Inherit Metab Dis; 2015 Sep; 38(5):797-805. PubMed ID: 25868666
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria.
    Bernardini G; Leone G; Millucci L; Consumi M; Braconi D; Spiga O; Galderisi S; Marzocchi B; Viti C; Giorgetti G; Lupetti P; Magnani A; Santucci A
    J Cell Physiol; 2019 May; 234(5):6696-6708. PubMed ID: 30341892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ochronotic pigmentation is caused by homogentisic acid and is the key event in alkaptonuria leading to the destructive consequences of the disease-A review.
    Ranganath LR; Norman BP; Gallagher JA
    J Inherit Metab Dis; 2019 Sep; 42(5):776-792. PubMed ID: 31282009
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel ex vivo organotypic culture model of alkaptonuria-ochronosis.
    Tinti L; Spreafico A; Chellini F; Galeazzi M; Santucci A
    Clin Exp Rheumatol; 2011; 29(4):693-6. PubMed ID: 21813063
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone.
    Preston AJ; Keenan CM; Sutherland H; Wilson PJ; Wlodarski B; Taylor AM; Williams DP; Ranganath LR; Gallagher JA; Jarvis JC
    Ann Rheum Dis; 2014 Jan; 73(1):284-9. PubMed ID: 23511227
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical and proteomic characterization of alkaptonuric chondrocytes.
    Braconi D; Bernardini G; Bianchini C; Laschi M; Millucci L; Amato L; Tinti L; Serchi T; Chellini F; Spreafico A; Santucci A
    J Cell Physiol; 2012 Sep; 227(9):3333-43. PubMed ID: 22213341
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria.
    Galderisi S; Milella MS; Rossi M; Cicaloni V; Rossi R; Giustarini D; Spiga O; Tinti L; Salvini L; Tinti C; Braconi D; Millucci L; Lupetti P; Prischi F; Bernardini G; Santucci A
    Arch Biochem Biophys; 2022 Mar; 717():109137. PubMed ID: 35090868
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxidative stress and mechanisms of ochronosis in alkaptonuria.
    Braconi D; Millucci L; Bernardini G; Santucci A
    Free Radic Biol Med; 2015 Nov; 88(Pt A):70-80. PubMed ID: 25733348
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria.
    Gambassi S; Geminiani M; Thorpe SD; Bernardini G; Millucci L; Braconi D; Orlandini M; Thompson CL; Petricci E; Manetti F; Taddei M; Knight MM; Santucci A
    J Cell Physiol; 2017 Nov; 232(11):3103-3111. PubMed ID: 28019670
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of an in vitro model to investigate joint ochronosis in alkaptonuria.
    Tinti L; Taylor AM; Santucci A; Wlodarski B; Wilson PJ; Jarvis JC; Fraser WD; Davidson JS; Ranganath LR; Gallagher JA
    Rheumatology (Oxford); 2011 Feb; 50(2):271-7. PubMed ID: 20952450
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage.
    Chow WY; Norman BP; Roberts NB; Ranganath LR; Teutloff C; Bittl R; Duer MJ; Gallagher JA; Oschkinat H
    Angew Chem Int Ed Engl; 2020 Jul; 59(29):11937-11942. PubMed ID: 32219972
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alkaptonuria: a very rare metabolic disorder.
    Aquaron R
    Indian J Biochem Biophys; 2013 Oct; 50(5):339-44. PubMed ID: 24772955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins.
    Braconi D; Millucci L; Bernini A; Spiga O; Lupetti P; Marzocchi B; Niccolai N; Bernardini G; Santucci A
    Biochim Biophys Acta Gen Subj; 2017 Feb; 1861(2):135-146. PubMed ID: 27865997
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis.
    Taylor AM; Jenks DD; Kammath VD; Norman BP; Dillon JP; Gallagher JA; Ranganath LR; Kerns JG
    Osteoarthritis Cartilage; 2019 Aug; 27(8):1244-1251. PubMed ID: 31022456
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria.
    Taylor AM; Boyde A; Wilson PJ; Jarvis JC; Davidson JS; Hunt JA; Ranganath LR; Gallagher JA
    Arthritis Rheum; 2011 Dec; 63(12):3887-96. PubMed ID: 22127706
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of antioxidant drugs for the treatment of ochronotic alkaptonuria in an in vitro human cell model.
    Tinti L; Spreafico A; Braconi D; Millucci L; Bernardini G; Chellini F; Cavallo G; Selvi E; Galeazzi M; Marcolongo R; Gallagher JA; Santucci A
    J Cell Physiol; 2010 Oct; 225(1):84-91. PubMed ID: 20648626
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytoskeleton Aberrations in Alkaptonuric Chondrocytes.
    Geminiani M; Gambassi S; Millucci L; Lupetti P; Collodel G; Mazzi L; Frediani B; Braconi D; Marzocchi B; Laschi M; Bernardini G; Santucci A
    J Cell Physiol; 2017 Jul; 232(7):1728-1738. PubMed ID: 27454006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria.
    Thorpe SD; Gambassi S; Thompson CL; Chandrakumar C; Santucci A; Knight MM
    J Cell Physiol; 2017 Sep; 232(9):2407-2417. PubMed ID: 28158906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.