298 related articles for article (PubMed ID: 28193319)
1. A conformational switch regulates the ubiquitin ligase HUWE1.
Sander B; Xu W; Eilers M; Popov N; Lorenz S
Elife; 2017 Feb; 6():. PubMed ID: 28193319
[TBL] [Abstract][Full Text] [Related]
2. Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Hunkeler M; Jin CY; Ma MW; Monda JK; Overwijn D; Bennett EJ; Fischer ES
Mol Cell; 2021 Sep; 81(17):3468-3480.e7. PubMed ID: 34314700
[TBL] [Abstract][Full Text] [Related]
3. A structural element within the HUWE1 HECT domain modulates self-ubiquitination and substrate ubiquitination activities.
Pandya RK; Partridge JR; Love KR; Schwartz TU; Ploegh HL
J Biol Chem; 2010 Feb; 285(8):5664-73. PubMed ID: 20007713
[TBL] [Abstract][Full Text] [Related]
4. The structure and regulation of the E3 ubiquitin ligase HUWE1 and its biological functions in cancer.
Gong X; Du D; Deng Y; Zhou Y; Sun L; Yuan S
Invest New Drugs; 2020 Apr; 38(2):515-524. PubMed ID: 32008177
[TBL] [Abstract][Full Text] [Related]
5. A novel SNP in HUWE1 promoter confers increased risk of NOA by affecting the RA/RARα pathway in Chinese individuals.
Shan X; Zhang X; Huang G; Lv J; Ye Z; Jiang C; Jiang X; Cheng J; Lin H; Jiang H; Yue H; Wang Z; Xu W
Andrology; 2024 Feb; 12(2):338-348. PubMed ID: 37290064
[TBL] [Abstract][Full Text] [Related]
6. β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.
Jäckl M; Stollmaier C; Strohäker T; Hyz K; Maspero E; Polo S; Wiesner S
J Mol Biol; 2018 Sep; 430(18 Pt B):3218-3233. PubMed ID: 29964046
[TBL] [Abstract][Full Text] [Related]
7. Crystal structure of the catalytic C-lobe of the HECT-type ubiquitin ligase E6AP.
Ries LK; Liess AKL; Feiler CG; Spratt DE; Lowe ED; Lorenz S
Protein Sci; 2020 Jun; 29(6):1550-1554. PubMed ID: 31994269
[TBL] [Abstract][Full Text] [Related]
8. The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.
Aleidi SM; Howe V; Sharpe LJ; Yang A; Rao G; Brown AJ; Gelissen IC
J Biol Chem; 2015 Oct; 290(40):24604-13. PubMed ID: 26296893
[TBL] [Abstract][Full Text] [Related]
9. Roles of the HUWE1 ubiquitin ligase in nervous system development, function and disease.
Giles AC; Grill B
Neural Dev; 2020 Apr; 15(1):6. PubMed ID: 32336296
[TBL] [Abstract][Full Text] [Related]
10. HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Grabarczyk DB; Petrova OA; Deszcz L; Kurzbauer R; Murphy P; Ahel J; Vogel A; Gogova R; Faas V; Kordic D; Schleiffer A; Meinhart A; Imre R; Lehner A; Neuhold J; Bader G; Stolt-Bergner P; Böttcher J; Wolkerstorfer B; Fischer G; Grishkovskaya I; Haselbach D; Kessler D; Clausen T
Nat Chem Biol; 2021 Oct; 17(10):1084-1092. PubMed ID: 34294896
[TBL] [Abstract][Full Text] [Related]
11. ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells.
Lee J; Kim J; Shin J; Kang Y; Choi J; Cheong H
Int J Mol Sci; 2021 Aug; 22(17):. PubMed ID: 34502089
[TBL] [Abstract][Full Text] [Related]
12. Tobramycin suppresses HUWE1 degradation to control MCL-1 stability during tumour development.
He J; Wu S; Li X; Tang L; Chen H; Qin L; Xie J; Lu T; Xu W
Clin Exp Pharmacol Physiol; 2020 Sep; 47(9):1600-1610. PubMed ID: 32378766
[TBL] [Abstract][Full Text] [Related]
13. The E3 ubiquitin ligase HUWE1 acts through the N-Myc-DLL1-NOTCH1 signaling axis to suppress glioblastoma progression.
Yuan Y; Wang LH; Zhao XX; Wang J; Zhang MS; Ma QH; Wei S; Yan ZX; Cheng Y; Chen XQ; Zou HB; Ge J; Wang Y; Zhang X; Cui YH; Luo T; Bian XW
Cancer Commun (Lond); 2022 Sep; 42(9):868-886. PubMed ID: 35848447
[TBL] [Abstract][Full Text] [Related]
14. Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.
Thompson JW; Nagel J; Hoving S; Gerrits B; Bauer A; Thomas JR; Kirschner MW; Schirle M; Luchansky SJ
J Biol Chem; 2014 Oct; 289(42):28942-55. PubMed ID: 25147182
[TBL] [Abstract][Full Text] [Related]
15. The giant E3 ligase HUWE1 is linked to tumorigenesis, spermatogenesis, intellectual disability, and inflammatory diseases.
Qi L; Xu X; Qi X
Front Cell Infect Microbiol; 2022; 12():905906. PubMed ID: 35937685
[TBL] [Abstract][Full Text] [Related]
16. Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.
Cheng YF; Tong M; Edge AS
J Biol Chem; 2016 Sep; 291(40):21096-21109. PubMed ID: 27542412
[TBL] [Abstract][Full Text] [Related]
17. Direct regulation of Chk1 protein stability by E3 ubiquitin ligase HUWE1.
Cassidy KB; Bang S; Kurokawa M; Gerber SA
FEBS J; 2020 May; 287(10):1985-1999. PubMed ID: 31713291
[TBL] [Abstract][Full Text] [Related]
18. Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Michel MA; Swatek KN; Hospenthal MK; Komander D
Mol Cell; 2017 Oct; 68(1):233-246.e5. PubMed ID: 28943312
[TBL] [Abstract][Full Text] [Related]
19. HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.
Jang ER; Shi P; Bryant J; Chen J; Dukhande V; Gentry MS; Jang H; Jeoung M; Galperin E
Mol Cell Biol; 2014 Oct; 34(19):3579-93. PubMed ID: 25022756
[TBL] [Abstract][Full Text] [Related]
20. Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage.
Hall JR; Kow E; Nevis KR; Lu CK; Luce KS; Zhong Q; Cook JG
Mol Biol Cell; 2007 Sep; 18(9):3340-50. PubMed ID: 17567951
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
