92 related articles for article (PubMed ID: 28207202)
1. The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network.
Liu J; Li F; Bao H; Jiang Y; Zhang S; Ma R; Gao J; Wu J; Ruan K
FEBS J; 2017 Apr; 284(7):1082-1095. PubMed ID: 28207202
[TBL] [Abstract][Full Text] [Related]
2. Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
Palmer WS; Poncet-Montange G; Liu G; Petrocchi A; Reyna N; Subramanian G; Theroff J; Yau A; Kost-Alimova M; Bardenhagen JP; Leo E; Shepard HE; Tieu TN; Shi X; Zhan Y; Zhao S; Barton MC; Draetta G; Toniatti C; Jones P; Geck Do M; Andersen JN
J Med Chem; 2016 Feb; 59(4):1440-54. PubMed ID: 26061247
[TBL] [Abstract][Full Text] [Related]
3. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands.
Gechijian LN; Buckley DL; Lawlor MA; Reyes JM; Paulk J; Ott CJ; Winter GE; Erb MA; Scott TG; Xu M; Seo HS; Dhe-Paganon S; Kwiatkowski NP; Perry JA; Qi J; Gray NS; Bradner JE
Nat Chem Biol; 2018 Apr; 14(4):405-412. PubMed ID: 29507391
[TBL] [Abstract][Full Text] [Related]
4. Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Bennett J; Fedorov O; Tallant C; Monteiro O; Meier J; Gamble V; Savitsky P; Nunez-Alonso GA; Haendler B; Rogers C; Brennan PE; Müller S; Knapp S
J Med Chem; 2016 Feb; 59(4):1642-7. PubMed ID: 25974391
[TBL] [Abstract][Full Text] [Related]
5. The NMR solution structure and function of RPA3313: a putative ribosomal transport protein from Rhodopseudomonas palustris.
Catazaro J; Lowe AJ; Cerny RL; Powers R
Proteins; 2017 Jan; 85(1):93-102. PubMed ID: 27802574
[TBL] [Abstract][Full Text] [Related]
6. A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Kozlyuk N; Gilston BA; Salay LE; Gogliotti RD; Christov PP; Kim K; Ovee M; Waterson AG; Chazin WJ
Proteins; 2021 Nov; 89(11):1399-1412. PubMed ID: 34156100
[TBL] [Abstract][Full Text] [Related]
7. Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors.
Xiang Q; Luo G; Zhang C; Hu Q; Wang C; Wu T; Xu H; Hu J; Zhuang X; Zhang M; Wu S; Xu J; Zhang Y; Liu J; Xu Y
Eur J Med Chem; 2022 Jun; 236():114311. PubMed ID: 35385803
[TBL] [Abstract][Full Text] [Related]
8. Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
Zhu J; Caflisch A
J Med Chem; 2016 Jun; 59(11):5555-61. PubMed ID: 27167503
[TBL] [Abstract][Full Text] [Related]
9. Cross-talk between chromatin acetylation and SUMOylation of tripartite motif-containing protein 24 (TRIM24) impacts cell adhesion.
Appikonda S; Thakkar KN; Shah PK; Dent SYR; Andersen JN; Barton MC
J Biol Chem; 2018 May; 293(19):7476-7485. PubMed ID: 29523690
[TBL] [Abstract][Full Text] [Related]
10. TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer.
Groner AC; Cato L; de Tribolet-Hardy J; Bernasocchi T; Janouskova H; Melchers D; Houtman R; Cato ACB; Tschopp P; Gu L; Corsinotti A; Zhong Q; Fankhauser C; Fritz C; Poyet C; Wagner U; Guo T; Aebersold R; Garraway LA; Wild PJ; Theurillat JP; Brown M
Cancer Cell; 2016 Jun; 29(6):846-858. PubMed ID: 27238081
[TBL] [Abstract][Full Text] [Related]
11. Discovery and optimization of novel N-benzyl-3,6-dimethylbenzo[d]isoxazol-5-amine derivatives as potent and selective TRIM24 bromodomain inhibitors with potential anti-cancer activities.
Hu Q; Wang C; Xiang Q; Wang R; Zhang C; Zhang M; Xue X; Luo G; Liu X; Wu X; Zhang Y; Wu D; Xu Y
Bioorg Chem; 2020 Jan; 94():103424. PubMed ID: 31776034
[TBL] [Abstract][Full Text] [Related]
12. Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
Cura V; Marechal N; Troffer-Charlier N; Strub JM; van Haren MJ; Martin NI; Cianférani S; Bonnefond L; Cavarelli J
FEBS J; 2017 Jan; 284(1):77-96. PubMed ID: 27879050
[TBL] [Abstract][Full Text] [Related]
13. Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands.
Elegheert J; Brigé A; Van Beeumen J; Savvides SN
FEBS Lett; 2017 Oct; 591(20):3391-3401. PubMed ID: 28869767
[TBL] [Abstract][Full Text] [Related]
14. Structural basis for binding and transfer of heme in bacterial heme-acquisition systems.
Naoe Y; Nakamura N; Rahman MM; Tosha T; Nagatoishi S; Tsumoto K; Shiro Y; Sugimoto H
Proteins; 2017 Dec; 85(12):2217-2230. PubMed ID: 28913898
[TBL] [Abstract][Full Text] [Related]
15. Insight into the key interactions of bromodomain inhibitors based on molecular docking, interaction fingerprinting, molecular dynamics and binding free energy calculation.
Ran T; Zhang Z; Liu K; Lu Y; Li H; Xu J; Xiong X; Zhang Y; Xu A; Lu S; Liu H; Lu T; Chen Y
Mol Biosyst; 2015 May; 11(5):1295-304. PubMed ID: 25758752
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW.
Fujita S; Cho SH; Yoshida A; Hasebe F; Tomita T; Kuzuyama T; Nishiyama M
Biochem Biophys Res Commun; 2017 Sep; 491(2):409-415. PubMed ID: 28720495
[TBL] [Abstract][Full Text] [Related]
17. Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain.
Spiliotopoulos D; Zhu J; Wamhoff EC; Deerain N; Marchand JR; Aretz J; Rademacher C; Caflisch A
Bioorg Med Chem Lett; 2017 Jun; 27(11):2472-2478. PubMed ID: 28410781
[TBL] [Abstract][Full Text] [Related]
18. Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery.
Zhan Y; Kost-Alimova M; Shi X; Leo E; Bardenhagen JP; Shepard HE; Appikonda S; Vangamudi B; Zhao S; Tieu TN; Jiang S; Heffernan TP; Marszalek JR; Toniatti C; Draetta G; Tyler J; Barton M; Jones P; Palmer WS; Geck Do MK; Andersen JN
Epigenetics Chromatin; 2015; 8():37. PubMed ID: 26396593
[TBL] [Abstract][Full Text] [Related]
19. X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site.
Yoshida H; Nishi N; Wada K; Nakamura T; Hirashima M; Kuwabara N; Kato R; Kamitori S
Biochem Biophys Res Commun; 2017 Sep; 490(4):1287-1293. PubMed ID: 28687490
[TBL] [Abstract][Full Text] [Related]
20. Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Zhang Q; Zeng L; Zhao C; Ju Y; Konuma T; Zhou MM
Structure; 2016 Sep; 24(9):1606-12. PubMed ID: 27545619
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
